Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | TPA_SENS_MIDDLE_UP |
| Enrichment Score (ES) | -0.60187757 |
| Normalized Enrichment Score (NES) | -1.9449714 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.015060314 |
| FWER p-Value | 0.428 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.0460 | No |
| 2 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 300 | 0.149 | 0.0582 | No |
| 3 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 475 | 0.128 | 0.0705 | No |
| 4 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 503 | 0.125 | 0.0933 | No |
| 5 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 583 | 0.119 | 0.1111 | No |
| 6 | SLC13A3 | SLC13A3 Entrez, Source | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 675 | 0.114 | 0.1269 | No |
| 7 | KCNN3 | KCNN3 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 884 | 0.103 | 0.1318 | No |
| 8 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 1732 | 0.074 | 0.0828 | No |
| 9 | AGER | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 3977 | 0.037 | -0.0787 | No |
| 10 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 4706 | 0.027 | -0.1280 | No |
| 11 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | -0.1726 | No |
| 12 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 6150 | 0.011 | -0.2302 | No |
| 13 | CLK3 | CLK3 Entrez, Source | CDC-like kinase 3 | 6845 | 0.004 | -0.2817 | No |
| 14 | PREP | PREP Entrez, Source | prolyl endopeptidase | 6861 | 0.004 | -0.2821 | No |
| 15 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 7574 | -0.005 | -0.3347 | No |
| 16 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 7648 | -0.005 | -0.3392 | No |
| 17 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 7690 | -0.006 | -0.3411 | No |
| 18 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 7711 | -0.006 | -0.3414 | No |
| 19 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 7802 | -0.007 | -0.3468 | No |
| 20 | AQP4 | AQP4 Entrez, Source | aquaporin 4 | 8023 | -0.010 | -0.3614 | No |
| 21 | PIK3CB | PIK3CB Entrez, Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 8066 | -0.010 | -0.3625 | No |
| 22 | RHOH | RHOH Entrez, Source | ras homolog gene family, member H | 8155 | -0.011 | -0.3669 | No |
| 23 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 8651 | -0.017 | -0.4006 | No |
| 24 | HSPA8 | HSPA8 Entrez, Source | heat shock 70kDa protein 8 | 8850 | -0.020 | -0.4116 | No |
| 25 | RPS6KA1 | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 9175 | -0.024 | -0.4311 | No |
| 26 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 9192 | -0.024 | -0.4275 | No |
| 27 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10388 | -0.043 | -0.5088 | No |
| 28 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 11391 | -0.065 | -0.5712 | No |
| 29 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 11800 | -0.079 | -0.5861 | Yes |
| 30 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 11983 | -0.086 | -0.5827 | Yes |
| 31 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12170 | -0.095 | -0.5777 | Yes |
| 32 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 12221 | -0.098 | -0.5619 | Yes |
| 33 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12330 | -0.106 | -0.5490 | Yes |
| 34 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 12561 | -0.122 | -0.5420 | Yes |
| 35 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 12657 | -0.130 | -0.5232 | Yes |
| 36 | AGA | AGA Entrez, Source | aspartylglucosaminidase | 12681 | -0.133 | -0.4984 | Yes |
| 37 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12748 | -0.141 | -0.4754 | Yes |
| 38 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12771 | -0.144 | -0.4484 | Yes |
| 39 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 12825 | -0.152 | -0.4221 | Yes |
| 40 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12886 | -0.162 | -0.3944 | Yes |
| 41 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 12938 | -0.173 | -0.3637 | Yes |
| 42 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 12974 | -0.182 | -0.3301 | Yes |
| 43 | VIM | VIM Entrez, Source | vimentin | 13040 | -0.204 | -0.2944 | Yes |
| 44 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13060 | -0.212 | -0.2536 | Yes |
| 45 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13163 | -0.267 | -0.2080 | Yes |
| 46 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.1224 | Yes |
| 47 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13326 | -0.627 | 0.0012 | Yes |
