Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | TPOPATHWAY |
| Enrichment Score (ES) | 0.55553156 |
| Normalized Enrichment Score (NES) | 1.6092151 |
| Nominal p-value | 0.031120332 |
| FDR q-value | 0.09199581 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.5555 | Yes |
| 2 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 1674 | 0.075 | 0.4711 | No |
| 3 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 2284 | 0.062 | 0.4597 | No |
| 4 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 2417 | 0.060 | 0.4827 | No |
| 5 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2668 | 0.056 | 0.4947 | No |
| 6 | THPO | THPO Entrez, Source | thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) | 3345 | 0.045 | 0.4687 | No |
| 7 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 4579 | 0.029 | 0.3921 | No |
| 8 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 6997 | 0.002 | 0.2117 | No |
| 9 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 7024 | 0.002 | 0.2106 | No |
| 10 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 7179 | 0.000 | 0.1991 | No |
| 11 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 7310 | -0.002 | 0.1902 | No |
| 12 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 7619 | -0.005 | 0.1698 | No |
| 13 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | 0.1409 | No |
| 14 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | 0.1372 | No |
| 15 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 8330 | -0.013 | 0.1363 | No |
| 16 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 9067 | -0.023 | 0.0935 | No |
| 17 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | 0.0926 | No |
| 18 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 9416 | -0.028 | 0.0967 | No |
| 19 | PLCG1 | PLCG1 Entrez, Source | phospholipase C, gamma 1 | 11883 | -0.083 | -0.0431 | No |
| 20 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.0301 | No |
| 21 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 12788 | -0.146 | 0.0416 | No |
