Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | TYROSINE_METABOLISM |
| Enrichment Score (ES) | 0.6210999 |
| Normalized Enrichment Score (NES) | 1.8948725 |
| Nominal p-value | 0.004651163 |
| FDR q-value | 0.016824644 |
| FWER p-Value | 0.565 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 19 | 0.354 | 0.1728 | Yes |
| 2 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 113 | 0.213 | 0.2707 | Yes |
| 3 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.3498 | Yes |
| 4 | TAT | TAT Entrez, Source | tyrosine aminotransferase | 428 | 0.132 | 0.3976 | Yes |
| 5 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 457 | 0.129 | 0.4590 | Yes |
| 6 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 489 | 0.126 | 0.5187 | Yes |
| 7 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 507 | 0.124 | 0.5786 | Yes |
| 8 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 1365 | 0.084 | 0.5554 | Yes |
| 9 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 1443 | 0.081 | 0.5896 | Yes |
| 10 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 1556 | 0.078 | 0.6197 | Yes |
| 11 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 1987 | 0.068 | 0.6211 | Yes |
| 12 | COMT | COMT Entrez, Source | catechol-O-methyltransferase | 2832 | 0.053 | 0.5836 | No |
| 13 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 3260 | 0.046 | 0.5744 | No |
| 14 | TPO | TPO Entrez, Source | thyroid peroxidase | 3752 | 0.040 | 0.5571 | No |
| 15 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 4512 | 0.030 | 0.5149 | No |
| 16 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 5177 | 0.022 | 0.4757 | No |
| 17 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6235 | 0.011 | 0.4015 | No |
| 18 | TH | TH Entrez, Source | tyrosine hydroxylase | 6759 | 0.005 | 0.3645 | No |
| 19 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 6812 | 0.004 | 0.3626 | No |
| 20 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 7461 | -0.003 | 0.3156 | No |
| 21 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8248 | -0.012 | 0.2626 | No |
| 22 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 8794 | -0.019 | 0.2312 | No |
| 23 | DBH | DBH Entrez, Source | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 11484 | -0.068 | 0.0626 | No |
| 24 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12850 | -0.156 | 0.0369 | No |
