Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | UEDA_MOUSE_LIVER |
| Enrichment Score (ES) | 0.43062922 |
| Normalized Enrichment Score (NES) | 1.7845702 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.035863016 |
| FWER p-Value | 0.938 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 13 | 0.382 | 0.0339 | Yes |
| 2 | ELOVL6 | ELOVL6 Entrez, Source | ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 29 | 0.313 | 0.0613 | Yes |
| 3 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 36 | 0.306 | 0.0887 | Yes |
| 4 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 40 | 0.295 | 0.1153 | Yes |
| 5 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 42 | 0.293 | 0.1420 | Yes |
| 6 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 46 | 0.289 | 0.1681 | Yes |
| 7 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 55 | 0.278 | 0.1928 | Yes |
| 8 | AQP9 | AQP9 Entrez, Source | aquaporin 9 | 57 | 0.272 | 0.2175 | Yes |
| 9 | FASN | FASN Entrez, Source | fatty acid synthase | 60 | 0.267 | 0.2418 | Yes |
| 10 | PDIA4 | PDIA4 Entrez, Source | protein disulfide isomerase family A, member 4 | 151 | 0.192 | 0.2524 | Yes |
| 11 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 155 | 0.190 | 0.2696 | Yes |
| 12 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 171 | 0.184 | 0.2852 | Yes |
| 13 | ERBB3 | ERBB3 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 235 | 0.163 | 0.2952 | Yes |
| 14 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 247 | 0.160 | 0.3090 | Yes |
| 15 | ASL | ASL Entrez, Source | argininosuccinate lyase | 273 | 0.154 | 0.3211 | Yes |
| 16 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 300 | 0.149 | 0.3328 | Yes |
| 17 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 368 | 0.139 | 0.3404 | Yes |
| 18 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 381 | 0.138 | 0.3521 | Yes |
| 19 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 432 | 0.132 | 0.3603 | Yes |
| 20 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 469 | 0.128 | 0.3693 | Yes |
| 21 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 498 | 0.125 | 0.3785 | Yes |
| 22 | SERPINF2 | SERPINF2 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 621 | 0.117 | 0.3800 | Yes |
| 23 | CES3 | CES3 Entrez, Source | carboxylesterase 3 (brain) | 629 | 0.116 | 0.3901 | Yes |
| 24 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 652 | 0.115 | 0.3989 | Yes |
| 25 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 716 | 0.111 | 0.4043 | Yes |
| 26 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 728 | 0.110 | 0.4135 | Yes |
| 27 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 732 | 0.110 | 0.4233 | Yes |
| 28 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 766 | 0.108 | 0.4306 | Yes |
| 29 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 939 | 0.100 | 0.4267 | No |
| 30 | ARL6IP2 | ARL6IP2 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 2 | 1087 | 0.094 | 0.4242 | No |
| 31 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 1441 | 0.081 | 0.4049 | No |
| 32 | TMEM150 | TMEM150 Entrez, Source | transmembrane protein 150 | 1446 | 0.081 | 0.4120 | No |
| 33 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 1459 | 0.081 | 0.4185 | No |
| 34 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 1464 | 0.080 | 0.4255 | No |
| 35 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 1585 | 0.077 | 0.4235 | No |
| 36 | FOXA3 | FOXA3 Entrez, Source | forkhead box A3 | 1938 | 0.069 | 0.4032 | No |
| 37 | FBXO8 | FBXO8 Entrez, Source | F-box protein 8 | 1968 | 0.069 | 0.4073 | No |
| 38 | TSPAN4 | TSPAN4 Entrez, Source | tetraspanin 4 | 2173 | 0.064 | 0.3978 | No |
| 39 | AK3L1 | AK3L1 Entrez, Source | adenylate kinase 3-like 1 | 2337 | 0.061 | 0.3911 | No |
| 40 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2418 | 0.060 | 0.3905 | No |
| 41 | CD9 | CD9 Entrez, Source | CD9 molecule | 2527 | 0.058 | 0.3876 | No |
| 42 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 2561 | 0.058 | 0.3904 | No |
| 43 | CYP8B1 | CYP8B1 Entrez, Source | cytochrome P450, family 8, subfamily B, polypeptide 1 | 2566 | 0.057 | 0.3953 | No |
| 44 | DNAJB11 | DNAJB11 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 11 | 2627 | 0.056 | 0.3959 | No |
| 45 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 2690 | 0.055 | 0.3963 | No |
| 46 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2958 | 0.051 | 0.3807 | No |
| 47 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 3543 | 0.042 | 0.3404 | No |
| 48 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 3549 | 0.042 | 0.3439 | No |
| 49 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 4134 | 0.035 | 0.3029 | No |
| 50 | HES6 | HES6 Entrez, Source | hairy and enhancer of split 6 (Drosophila) | 4366 | 0.032 | 0.2884 | No |
| 51 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4382 | 0.032 | 0.2901 | No |
| 52 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 4425 | 0.031 | 0.2898 | No |
| 53 | FKBP4 | FKBP4 Entrez, Source | FK506 binding protein 4, 59kDa | 4626 | 0.028 | 0.2773 | No |
| 54 | LGALS9 | LGALS9 Entrez, Source | lectin, galactoside-binding, soluble, 9 (galectin 9) | 4715 | 0.027 | 0.2731 | No |
| 55 | NR1D2 | NR1D2 Entrez, Source | nuclear receptor subfamily 1, group D, member 2 | 4748 | 0.027 | 0.2731 | No |
| 56 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 4765 | 0.027 | 0.2744 | No |
| 57 | MKNK2 | MKNK2 Entrez, Source | MAP kinase interacting serine/threonine kinase 2 | 4889 | 0.025 | 0.2674 | No |
| 58 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 5269 | 0.021 | 0.2406 | No |
| 59 | SQSTM1 | SQSTM1 Entrez, Source | sequestosome 1 | 5369 | 0.020 | 0.2349 | No |
| 60 | CHKA | CHKA Entrez, Source | choline kinase alpha | 5540 | 0.018 | 0.2237 | No |
| 61 | TARS | TARS Entrez, Source | threonyl-tRNA synthetase | 5585 | 0.017 | 0.2220 | No |
| 62 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6058 | 0.012 | 0.1874 | No |
| 63 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6235 | 0.011 | 0.1751 | No |
| 64 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 6529 | 0.007 | 0.1536 | No |
| 65 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 6701 | 0.005 | 0.1412 | No |
| 66 | ST3GAL5 | ST3GAL5 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 7369 | -0.002 | 0.0910 | No |
| 67 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 7763 | -0.007 | 0.0619 | No |
| 68 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8593 | -0.017 | 0.0008 | No |
| 69 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.0048 | No |
| 70 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 8764 | -0.019 | -0.0086 | No |
| 71 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 8957 | -0.021 | -0.0212 | No |
| 72 | THRAP3 | THRAP3 Entrez, Source | thyroid hormone receptor associated protein 3 | 9086 | -0.023 | -0.0287 | No |
| 73 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 9384 | -0.027 | -0.0487 | No |
| 74 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 9406 | -0.028 | -0.0478 | No |
| 75 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 9640 | -0.031 | -0.0625 | No |
| 76 | MGEA5 | MGEA5 Entrez, Source | meningioma expressed antigen 5 (hyaluronidase) | 10016 | -0.037 | -0.0875 | No |
| 77 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 10060 | -0.038 | -0.0873 | No |
| 78 | PNRC1 | PNRC1 Entrez, Source | proline-rich nuclear receptor coactivator 1 | 10332 | -0.042 | -0.1040 | No |
| 79 | PER2 | PER2 Entrez, Source | period homolog 2 (Drosophila) | 10374 | -0.043 | -0.1031 | No |
| 80 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 10491 | -0.045 | -0.1078 | No |
| 81 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 10828 | -0.052 | -0.1284 | No |
| 82 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 10934 | -0.054 | -0.1314 | No |
| 83 | MESDC2 | MESDC2 Entrez, Source | mesoderm development candidate 2 | 11063 | -0.057 | -0.1359 | No |
| 84 | ABCB4 | ABCB4 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 11113 | -0.058 | -0.1343 | No |
| 85 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 11186 | -0.060 | -0.1342 | No |
| 86 | BRI3 | BRI3 Entrez, Source | brain protein I3 | 11585 | -0.071 | -0.1578 | No |
| 87 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 11726 | -0.076 | -0.1614 | No |
| 88 | LSR | LSR Entrez, Source | lipolysis stimulated lipoprotein receptor | 11762 | -0.078 | -0.1570 | No |
| 89 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 11763 | -0.078 | -0.1499 | No |
| 90 | FDX1 | FDX1 Entrez, Source | ferredoxin 1 | 11956 | -0.085 | -0.1567 | No |
| 91 | CLDN1 | CLDN1 Entrez, Source | claudin 1 | 12033 | -0.089 | -0.1543 | No |
| 92 | SLC9A3R1 | SLC9A3R1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 12048 | -0.089 | -0.1473 | No |
| 93 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 12221 | -0.098 | -0.1513 | No |
| 94 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12269 | -0.101 | -0.1457 | No |
| 95 | TUBB | TUBB Entrez, Source | tubulin, beta | 12364 | -0.108 | -0.1429 | No |
| 96 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 12427 | -0.112 | -0.1373 | No |
| 97 | FGF1 | FGF1 Entrez, Source | fibroblast growth factor 1 (acidic) | 12602 | -0.125 | -0.1391 | No |
| 98 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 12603 | -0.125 | -0.1276 | No |
| 99 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 12825 | -0.152 | -0.1305 | No |
| 100 | CD47 | CD47 Entrez, Source | CD47 molecule | 12956 | -0.177 | -0.1242 | No |
| 101 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 12965 | -0.179 | -0.1084 | No |
| 102 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12991 | -0.186 | -0.0934 | No |
| 103 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 13138 | -0.251 | -0.0815 | No |
| 104 | LMO7 | LMO7 Entrez, Source | LIM domain 7 | 13174 | -0.275 | -0.0591 | No |
| 105 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13224 | -0.321 | -0.0336 | No |
| 106 | AVPR1A | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 13299 | -0.465 | 0.0032 | No |
