Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | UVB_SCC_UP |
| Enrichment Score (ES) | -0.56616503 |
| Normalized Enrichment Score (NES) | -1.9081203 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.022684872 |
| FWER p-Value | 0.603 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 329 | 0.145 | 0.0079 | No |
| 2 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 1133 | 0.092 | -0.0318 | No |
| 3 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 1267 | 0.087 | -0.0222 | No |
| 4 | RBMXL1 | RBMXL1 Entrez, Source | RNA binding motif protein, X-linked-like 1 | 2072 | 0.066 | -0.0678 | No |
| 5 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 2158 | 0.065 | -0.0596 | No |
| 6 | SCFD1 | SCFD1 Entrez, Source | sec1 family domain containing 1 | 2286 | 0.062 | -0.0551 | No |
| 7 | ADK | ADK Entrez, Source | adenosine kinase | 2387 | 0.061 | -0.0490 | No |
| 8 | SCARB2 | SCARB2 Entrez, Source | scavenger receptor class B, member 2 | 3098 | 0.049 | -0.0914 | No |
| 9 | TAF2 | TAF2 Entrez, Source | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 3385 | 0.045 | -0.1029 | No |
| 10 | CCBP2 | CCBP2 Entrez, Source | chemokine binding protein 2 | 3686 | 0.041 | -0.1163 | No |
| 11 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 4061 | 0.035 | -0.1364 | No |
| 12 | PDIA6 | PDIA6 Entrez, Source | protein disulfide isomerase family A, member 6 | 4624 | 0.028 | -0.1724 | No |
| 13 | COPB1 | COPB1 Entrez, Source | coatomer protein complex, subunit beta 1 | 4753 | 0.027 | -0.1759 | No |
| 14 | JUND | JUND Entrez, Source | jun D proto-oncogene | 4884 | 0.025 | -0.1800 | No |
| 15 | TAGLN3 | TAGLN3 Entrez, Source | transgelin 3 | 4905 | 0.025 | -0.1759 | No |
| 16 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.1791 | No |
| 17 | UQCRC2 | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 5022 | 0.024 | -0.1739 | No |
| 18 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 5149 | 0.022 | -0.1784 | No |
| 19 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.1757 | No |
| 20 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 5418 | 0.019 | -0.1894 | No |
| 21 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 5622 | 0.017 | -0.2008 | No |
| 22 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 6080 | 0.012 | -0.2325 | No |
| 23 | CCNC | CCNC Entrez, Source | cyclin C | 6339 | 0.009 | -0.2499 | No |
| 24 | TSC22D3 | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 6484 | 0.008 | -0.2590 | No |
| 25 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.2867 | No |
| 26 | IL13RA1 | IL13RA1 Entrez, Source | interleukin 13 receptor, alpha 1 | 7219 | -0.000 | -0.3133 | No |
| 27 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 7360 | -0.002 | -0.3233 | No |
| 28 | PRDX3 | PRDX3 Entrez, Source | peroxiredoxin 3 | 7459 | -0.003 | -0.3300 | No |
| 29 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 7804 | -0.007 | -0.3543 | No |
| 30 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 7920 | -0.009 | -0.3610 | No |
| 31 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 7926 | -0.009 | -0.3594 | No |
| 32 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | -0.3787 | No |
| 33 | PTK9 | PTK9 Entrez, Source | PTK9 protein tyrosine kinase 9 | 8672 | -0.018 | -0.4087 | No |
| 34 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 8723 | -0.018 | -0.4084 | No |
| 35 | B2M | B2M Entrez, Source | beta-2-microglobulin | 9260 | -0.025 | -0.4430 | No |
| 36 | RECQL | RECQL Entrez, Source | RecQ protein-like (DNA helicase Q1-like) | 9327 | -0.026 | -0.4421 | No |
| 37 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9333 | -0.026 | -0.4365 | No |
| 38 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 9376 | -0.027 | -0.4336 | No |
| 39 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 9384 | -0.027 | -0.4280 | No |
| 40 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 9609 | -0.031 | -0.4379 | No |
| 41 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 9838 | -0.034 | -0.4475 | No |
| 42 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 10029 | -0.037 | -0.4534 | No |
| 43 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 10287 | -0.041 | -0.4635 | No |
| 44 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 10313 | -0.042 | -0.4559 | No |
| 45 | HSP90AB1 | HSP90AB1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 10450 | -0.044 | -0.4562 | No |
| 46 | ATP6AP2 | ATP6AP2 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 2 | 11566 | -0.071 | -0.5242 | No |
| 47 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 11843 | -0.081 | -0.5268 | No |
| 48 | DYNC2LI1 | DYNC2LI1 Entrez, Source | dynein, cytoplasmic 2, light intermediate chain 1 | 12337 | -0.106 | -0.5400 | Yes |
| 49 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12686 | -0.133 | -0.5361 | Yes |
| 50 | RALB | RALB Entrez, Source | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 12865 | -0.159 | -0.5138 | Yes |
| 51 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 12879 | -0.161 | -0.4784 | Yes |
| 52 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13112 | -0.236 | -0.4425 | Yes |
| 53 | RCN2 | RCN2 Entrez, Source | reticulocalbin 2, EF-hand calcium binding domain | 13116 | -0.238 | -0.3890 | Yes |
| 54 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 13167 | -0.269 | -0.3323 | Yes |
| 55 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.2641 | Yes |
| 56 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13254 | -0.355 | -0.1861 | Yes |
| 57 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 13267 | -0.380 | -0.1012 | Yes |
| 58 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13304 | -0.474 | 0.0029 | Yes |
