Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | UVC_TTD_4HR_DN |
| Enrichment Score (ES) | -0.49693394 |
| Normalized Enrichment Score (NES) | -1.8825725 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.026087817 |
| FWER p-Value | 0.723 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 292 | 0.150 | -0.0043 | No |
| 2 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 531 | 0.123 | -0.0077 | No |
| 3 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 652 | 0.115 | -0.0032 | No |
| 4 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 766 | 0.108 | 0.0011 | No |
| 5 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 960 | 0.099 | -0.0018 | No |
| 6 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 1285 | 0.086 | -0.0161 | No |
| 7 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1682 | 0.075 | -0.0372 | No |
| 8 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 1770 | 0.073 | -0.0352 | No |
| 9 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 2046 | 0.067 | -0.0480 | No |
| 10 | WDR7 | WDR7 Entrez, Source | WD repeat domain 7 | 2080 | 0.066 | -0.0427 | No |
| 11 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 2122 | 0.065 | -0.0380 | No |
| 12 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 2207 | 0.064 | -0.0368 | No |
| 13 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 2673 | 0.056 | -0.0654 | No |
| 14 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | -0.0599 | No |
| 15 | EDG2 | EDG2 Entrez, Source | endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 | 2966 | 0.051 | -0.0749 | No |
| 16 | TCF12 | TCF12 Entrez, Source | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | 3016 | 0.050 | -0.0727 | No |
| 17 | MGAT5 | MGAT5 Entrez, Source | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 3267 | 0.046 | -0.0862 | No |
| 18 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 3619 | 0.042 | -0.1078 | No |
| 19 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 3748 | 0.040 | -0.1128 | No |
| 20 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 3777 | 0.040 | -0.1102 | No |
| 21 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 4160 | 0.034 | -0.1350 | No |
| 22 | PTPN2 | PTPN2 Entrez, Source | protein tyrosine phosphatase, non-receptor type 2 | 4170 | 0.034 | -0.1317 | No |
| 23 | RSN | RSN Entrez, Source | restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) | 4173 | 0.034 | -0.1278 | No |
| 24 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 4254 | 0.033 | -0.1299 | No |
| 25 | HOMER1 | HOMER1 Entrez, Source | homer homolog 1 (Drosophila) | 4308 | 0.032 | -0.1301 | No |
| 26 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 4336 | 0.032 | -0.1283 | No |
| 27 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 4384 | 0.032 | -0.1281 | No |
| 28 | PTPN12 | PTPN12 Entrez, Source | protein tyrosine phosphatase, non-receptor type 12 | 5000 | 0.024 | -0.1718 | No |
| 29 | PEX14 | PEX14 Entrez, Source | peroxisomal biogenesis factor 14 | 5019 | 0.024 | -0.1704 | No |
| 30 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 5047 | 0.023 | -0.1697 | No |
| 31 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 5072 | 0.023 | -0.1688 | No |
| 32 | AFAP | AFAP Entrez, Source | - | 5277 | 0.021 | -0.1818 | No |
| 33 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | -0.1851 | No |
| 34 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 5552 | 0.018 | -0.1980 | No |
| 35 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 5764 | 0.015 | -0.2122 | No |
| 36 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 5790 | 0.015 | -0.2123 | No |
| 37 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 5810 | 0.015 | -0.2119 | No |
| 38 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 5955 | 0.013 | -0.2213 | No |
| 39 | ZHX3 | ZHX3 Entrez, Source | zinc fingers and homeoboxes 3 | 5985 | 0.013 | -0.2219 | No |
| 40 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 5990 | 0.013 | -0.2207 | No |
| 41 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 6017 | 0.013 | -0.2212 | No |
| 42 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 6045 | 0.012 | -0.2218 | No |
| 43 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 6186 | 0.011 | -0.2311 | No |
| 44 | PARG | PARG Entrez, Source | poly (ADP-ribose) glycohydrolase | 6188 | 0.011 | -0.2298 | No |
| 45 | RBM16 | RBM16 Entrez, Source | RNA binding motif protein 16 | 6416 | 0.008 | -0.2460 | No |
| 46 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 6428 | 0.008 | -0.2459 | No |
| 47 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 6449 | 0.008 | -0.2464 | No |
| 48 | PKN2 | PKN2 Entrez, Source | protein kinase N2 | 6600 | 0.006 | -0.2570 | No |
| 49 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 6692 | 0.006 | -0.2632 | No |
| 50 | ARNT2 | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 6735 | 0.005 | -0.2658 | No |
| 51 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 6751 | 0.005 | -0.2664 | No |
| 52 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 6964 | 0.002 | -0.2822 | No |
| 53 | TRIO | TRIO Entrez, Source | triple functional domain (PTPRF interacting) | 6995 | 0.002 | -0.2842 | No |
| 54 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 7310 | -0.002 | -0.3078 | No |
| 55 | RBM39 | RBM39 Entrez, Source | RNA binding motif protein 39 | 7326 | -0.002 | -0.3087 | No |
| 56 | SIPA1L1 | SIPA1L1 Entrez, Source | signal-induced proliferation-associated 1 like 1 | 7445 | -0.003 | -0.3173 | No |
| 57 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 7463 | -0.003 | -0.3182 | No |
| 58 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 7540 | -0.004 | -0.3234 | No |
| 59 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 7633 | -0.005 | -0.3298 | No |
| 60 | CEP350 | CEP350 Entrez, Source | centrosomal protein 350kDa | 7828 | -0.007 | -0.3436 | No |
| 61 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 7838 | -0.008 | -0.3434 | No |
| 62 | CNOT2 | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 7845 | -0.008 | -0.3429 | No |
| 63 | ATF2 | ATF2 Entrez, Source | activating transcription factor 2 | 7856 | -0.008 | -0.3427 | No |
| 64 | SLC4A7 | SLC4A7 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 7866 | -0.008 | -0.3425 | No |
| 65 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 7997 | -0.009 | -0.3512 | No |
| 66 | GULP1 | GULP1 Entrez, Source | GULP, engulfment adaptor PTB domain containing 1 | 8014 | -0.010 | -0.3513 | No |
| 67 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 8159 | -0.011 | -0.3608 | No |
| 68 | ARIH1 | ARIH1 Entrez, Source | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 8193 | -0.012 | -0.3619 | No |
| 69 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 8325 | -0.013 | -0.3703 | No |
| 70 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 8618 | -0.017 | -0.3903 | No |
| 71 | PUM2 | PUM2 Entrez, Source | pumilio homolog 2 (Drosophila) | 8893 | -0.020 | -0.4087 | No |
| 72 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 9017 | -0.022 | -0.4154 | No |
| 73 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 9145 | -0.024 | -0.4222 | No |
| 74 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 9194 | -0.024 | -0.4229 | No |
| 75 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 9318 | -0.026 | -0.4291 | No |
| 76 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 9654 | -0.031 | -0.4507 | No |
| 77 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 10173 | -0.039 | -0.4853 | No |
| 78 | MTF2 | MTF2 Entrez, Source | metal response element binding transcription factor 2 | 10194 | -0.040 | -0.4820 | No |
| 79 | SLIT1 | SLIT1 Entrez, Source | slit homolog 1 (Drosophila) | 10284 | -0.041 | -0.4839 | No |
| 80 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10315 | -0.042 | -0.4813 | No |
| 81 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 10375 | -0.043 | -0.4806 | No |
| 82 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 10387 | -0.043 | -0.4763 | No |
| 83 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 10642 | -0.048 | -0.4899 | No |
| 84 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 10736 | -0.050 | -0.4910 | Yes |
| 85 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10779 | -0.051 | -0.4881 | Yes |
| 86 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 10893 | -0.053 | -0.4903 | Yes |
| 87 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 10930 | -0.054 | -0.4866 | Yes |
| 88 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 11046 | -0.057 | -0.4886 | Yes |
| 89 | CNOT4 | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 11078 | -0.058 | -0.4841 | Yes |
| 90 | STRN3 | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 11105 | -0.058 | -0.4792 | Yes |
| 91 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11131 | -0.059 | -0.4742 | Yes |
| 92 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 11148 | -0.059 | -0.4684 | Yes |
| 93 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 11238 | -0.061 | -0.4679 | Yes |
| 94 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 11387 | -0.065 | -0.4714 | Yes |
| 95 | ZNF292 | ZNF292 Entrez, Source | zinc finger protein 292 | 11534 | -0.070 | -0.4742 | Yes |
| 96 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11670 | -0.074 | -0.4756 | Yes |
| 97 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 11687 | -0.075 | -0.4680 | Yes |
| 98 | TMEM23 | TMEM23 Entrez, Source | transmembrane protein 23 | 11708 | -0.076 | -0.4605 | Yes |
| 99 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 11776 | -0.078 | -0.4564 | Yes |
| 100 | MTMR3 | MTMR3 Entrez, Source | myotubularin related protein 3 | 11869 | -0.082 | -0.4537 | Yes |
| 101 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 11872 | -0.082 | -0.4441 | Yes |
| 102 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 11999 | -0.087 | -0.4434 | Yes |
| 103 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12079 | -0.091 | -0.4386 | Yes |
| 104 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12083 | -0.091 | -0.4281 | Yes |
| 105 | CEP170 | CEP170 Entrez, Source | centrosomal protein 170kDa | 12151 | -0.094 | -0.4220 | Yes |
| 106 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12376 | -0.109 | -0.4260 | Yes |
| 107 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 12549 | -0.121 | -0.4247 | Yes |
| 108 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12599 | -0.125 | -0.4136 | Yes |
| 109 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 12603 | -0.125 | -0.3989 | Yes |
| 110 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 12638 | -0.129 | -0.3863 | Yes |
| 111 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 12665 | -0.131 | -0.3727 | Yes |
| 112 | SYNJ2 | SYNJ2 Entrez, Source | synaptojanin 2 | 12666 | -0.131 | -0.3572 | Yes |
| 113 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 12733 | -0.139 | -0.3458 | Yes |
| 114 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12771 | -0.144 | -0.3315 | Yes |
| 115 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 13105 | -0.234 | -0.3290 | Yes |
| 116 | RRAS2 | RRAS2 Entrez, Source | related RAS viral (r-ras) oncogene homolog 2 | 13125 | -0.244 | -0.3016 | Yes |
| 117 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13180 | -0.281 | -0.2725 | Yes |
| 118 | SPBC25 | SPBC25 Entrez, Source | spindle pole body component 25 homolog (S. cerevisiae) | 13182 | -0.282 | -0.2392 | Yes |
| 119 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13215 | -0.309 | -0.2050 | Yes |
| 120 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13239 | -0.335 | -0.1671 | Yes |
| 121 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13298 | -0.461 | -0.1169 | Yes |
| 122 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13313 | -0.503 | -0.0584 | Yes |
| 123 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13315 | -0.511 | 0.0020 | Yes |
