Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classsingle_gel_48h
GeneSetUVC_TTD_ALL_DN
Enrichment Score (ES)-0.47068048
Normalized Enrichment Score (NES)-1.8467987
Nominal p-value0.0
FDR q-value0.03219426
FWER p-Value0.877
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVC_TTD_ALL_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B2920.150-0.0088No
2CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)2950.1500.0044No
3MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)3420.1430.0136No
4IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 35310.1230.0103No
5CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)6520.1150.0114No
6DPYDDPYD
Entrez,  Source
dihydropyrimidine dehydrogenase7450.1090.0142No
7BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 27660.1080.0223No
8CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)9400.1000.0180No
9DLC1DLC1
Entrez,  Source
deleted in liver cancer 19600.0990.0254No
10ATRXATRX
Entrez,  Source
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)10240.0960.0292No
11ENC1ENC1
Entrez,  Source
ectodermal-neural cortex (with BTB-like domain)11060.0930.0313No
12IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 112850.0860.0255No
13FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES16820.0750.0021No
14MDN1MDN1
Entrez,  Source
MDN1, midasin homolog (yeast)17700.0730.0020No
15MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)18960.070-0.0013No
16MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)20460.067-0.0066No
17WDR7WDR7
Entrez,  Source
WD repeat domain 720800.066-0.0032No
18GTF2F2GTF2F2
Entrez,  Source
general transcription factor IIF, polypeptide 2, 30kDa21130.0660.0002No
19HAS2HAS2
Entrez,  Source
hyaluronan synthase 221220.0650.0054No
20BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase22070.0640.0047No
21FGF5FGF5
Entrez,  Source
fibroblast growth factor 526730.056-0.0256No
22EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)26880.055-0.0218No
23EDG2EDG2
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 229660.051-0.0383No
24GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)29970.050-0.0361No
25TCF12TCF12
Entrez,  Source
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)30160.050-0.0330No
26MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase32670.046-0.0479No
27MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 636190.042-0.0708No
28MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 337480.040-0.0770No
29ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)37770.040-0.0756No
30FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)40240.036-0.0910No
31AMPHAMPH
Entrez,  Source
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)40750.035-0.0917No
32NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 341600.034-0.0950No
33PTPN2PTPN2
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 241700.034-0.0927No
34RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)41730.034-0.0898No
35ZRF1ZRF1
Entrez,  Source
zuotin related factor 142540.033-0.0929No
36HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)43080.032-0.0940No
37RGS7RGS7
Entrez,  Source
regulator of G-protein signalling 743360.032-0.0932No
38SPOPSPOP
Entrez,  Source
speckle-type POZ protein43840.032-0.0940No
39PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 1250000.024-0.1385No
40PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1450190.024-0.1378No
41NUP153NUP153
Entrez,  Source
nucleoporin 153kDa50470.023-0.1377No
42PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 150720.023-0.1375No
43DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 151170.022-0.1389No
44AFAPAFAP
Entrez,  Source
-52770.021-0.1491No
45TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 253530.020-0.1530No
46MGLLMGLL
Entrez,  Source
monoglyceride lipase54000.019-0.1548No
47ATXN1ATXN1
Entrez,  Source
ataxin 155520.018-0.1647No
48GPR176GPR176
Entrez,  Source
G protein-coupled receptor 17657270.016-0.1765No
49STK39STK39
Entrez,  Source
serine threonine kinase 39 (STE20/SPS1 homolog, yeast)57640.015-0.1778No
50EIF4EEIF4E
Entrez,  Source
eukaryotic translation initiation factor 4E57900.015-0.1784No
51TSPAN5TSPAN5
Entrez,  Source
tetraspanin 558100.015-0.1785No
52ACVR1ACVR1
Entrez,  Source
activin A receptor, type I59550.013-0.1882No
53ZHX3ZHX3
Entrez,  Source
zinc fingers and homeoboxes 359850.013-0.1893No
54PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)59900.013-0.1885No
55ORC2LORC2L
Entrez,  Source
origin recognition complex, subunit 2-like (yeast)60170.013-0.1893No
56TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 360450.012-0.1903No
57KLF10KLF10
Entrez,  Source
Kruppel-like factor 1061860.011-0.1999No
58PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase61880.011-0.1990No
59RBM16RBM16
Entrez,  Source
RNA binding motif protein 1664160.008-0.2155No
60NUP98NUP98
Entrez,  Source
nucleoporin 98kDa64280.008-0.2156No
61CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)64490.008-0.2164No
62PKN2PKN2
Entrez,  Source
protein kinase N266000.006-0.2272No
63MARCH7MARCH7
Entrez,  Source
membrane-associated ring finger (C3HC4) 766920.006-0.2336No
64ARNT2ARNT2
Entrez,  Source
aryl-hydrocarbon receptor nuclear translocator 267350.005-0.2363No
65ZNF148ZNF148
Entrez,  Source
zinc finger protein 14867510.005-0.2370No
66DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A69640.002-0.2529No
67TRIOTRIO
Entrez,  Source
triple functional domain (PTPRF interacting)69950.002-0.2550No
68PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha7310-0.002-0.2787No
69RBM39RBM39
Entrez,  Source
RNA binding motif protein 397326-0.002-0.2797No
70SIPA1L1SIPA1L1
Entrez,  Source
signal-induced proliferation-associated 1 like 17445-0.003-0.2883No
71PTPRKPTPRK
Entrez,  Source
protein tyrosine phosphatase, receptor type, K7463-0.003-0.2893No
72PPP2R2APPP2R2A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform7540-0.004-0.2947No
73HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like7633-0.005-0.3012No
74FUT8FUT8
Entrez,  Source
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)7725-0.006-0.3076No
75CEP350CEP350
Entrez,  Source
centrosomal protein 350kDa7828-0.007-0.3147No
76ATP2B1ATP2B1
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 17838-0.008-0.3147No
77CNOT2CNOT2
Entrez,  Source
CCR4-NOT transcription complex, subunit 27845-0.008-0.3145No
78ATF2ATF2
Entrez,  Source
activating transcription factor 27856-0.008-0.3145No
79SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 77866-0.008-0.3145No
80COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 27962-0.009-0.3209No
81FUBP1FUBP1
Entrez,  Source
far upstream element (FUSE) binding protein 17997-0.009-0.3226No
82GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 18014-0.010-0.3230No
83PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa8159-0.011-0.3329No
84ARIH1ARIH1
Entrez,  Source
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)8193-0.012-0.3344No
85BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 18325-0.013-0.3431No
86ACVR2AACVR2A
Entrez,  Source
activin A receptor, type IIA8618-0.017-0.3637No
87PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)8893-0.020-0.3827No
88PTPRMPTPRM
Entrez,  Source
protein tyrosine phosphatase, receptor type, M8923-0.021-0.3831No
89GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide9017-0.022-0.3881No
90CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 29145-0.024-0.3957No
91REV3LREV3L
Entrez,  Source
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)9194-0.024-0.3971No
92MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)9318-0.026-0.4041No
93MYO1BMYO1B
Entrez,  Source
myosin IB9460-0.028-0.4123No
94FARS2FARS2
Entrez,  Source
phenylalanine-tRNA synthetase 2 (mitochondrial)9474-0.029-0.4108No
95ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein9654-0.031-0.4215No
96CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)9898-0.035-0.4369No
97NIPBLNIPBL
Entrez,  Source
Nipped-B homolog (Drosophila)10173-0.039-0.4541No
98MTF2MTF2
Entrez,  Source
metal response element binding transcription factor 210194-0.040-0.4521No
99SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)10284-0.041-0.4552No
100MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 410315-0.042-0.4538No
101CUTL1CUTL1
Entrez,  Source
cut-like 1, CCAAT displacement protein (Drosophila)10375-0.043-0.4544No
102OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)10387-0.043-0.4514No
103CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b10642-0.048-0.4664Yes
104TDRD3TDRD3
Entrez,  Source
tudor domain containing 310671-0.048-0.4642Yes
105PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A10736-0.050-0.4646Yes
106PRIM2APRIM2A
Entrez,  Source
primase, polypeptide 2A, 58kDa10779-0.051-0.4633Yes
107SERPINB2SERPINB2
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 210863-0.053-0.4649Yes
108XRCC4XRCC4
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 410893-0.053-0.4623Yes
109PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 210930-0.054-0.4602Yes
110MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)11046-0.057-0.4639Yes
111CNOT4CNOT4
Entrez,  Source
CCR4-NOT transcription complex, subunit 411078-0.058-0.4611Yes
112ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 1111091-0.058-0.4569Yes
113SKAP2SKAP2
Entrez,  Source
src kinase associated phosphoprotein 211101-0.058-0.4524Yes
114STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311105-0.058-0.4475Yes
115SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11131-0.059-0.4442Yes
116TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)11148-0.059-0.4401Yes
117ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 711238-0.061-0.4414Yes
118SEPT9SEPT9
Entrez,  Source
septin 911321-0.063-0.4421Yes
119CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase11387-0.065-0.4412Yes
120ZNF292ZNF292
Entrez,  Source
zinc finger protein 29211534-0.070-0.4461Yes
121NFIBNFIB
Entrez,  Source
nuclear factor I/B11596-0.072-0.4444Yes
122NRG1NRG1
Entrez,  Source
neuregulin 111626-0.073-0.4401Yes
123GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11670-0.074-0.4367Yes
124FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)11687-0.075-0.4313Yes
125TMEM23TMEM23
Entrez,  Source
transmembrane protein 2311708-0.076-0.4261Yes
126UBL3UBL3
Entrez,  Source
ubiquitin-like 311776-0.078-0.4242Yes
127CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)11862-0.081-0.4234Yes
128MTMR3MTMR3
Entrez,  Source
myotubularin related protein 311869-0.082-0.4166Yes
129CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 211872-0.082-0.4095Yes
130STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)11999-0.087-0.4113Yes
131PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 212079-0.091-0.4092Yes
132LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog12083-0.091-0.4014Yes
133CEP170CEP170
Entrez,  Source
centrosomal protein 170kDa12151-0.094-0.3981Yes
134ABI1ABI1
Entrez,  Source
abl-interactor 112376-0.109-0.4054Yes
135PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase12549-0.121-0.4076Yes
136ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212599-0.125-0.4002Yes
137PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 112603-0.125-0.3893Yes
138CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 112638-0.129-0.3804Yes
139VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C12665-0.131-0.3708Yes
140SYNJ2SYNJ2
Entrez,  Source
synaptojanin 212666-0.131-0.3591Yes
141KIF2AKIF2A
Entrez,  Source
kinesin heavy chain member 2A12733-0.139-0.3518Yes
142IL1RAPIL1RAP
Entrez,  Source
interleukin 1 receptor accessory protein12771-0.144-0.3418Yes
143UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase13105-0.234-0.3462Yes
144RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 213125-0.244-0.3260Yes
145RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)13180-0.281-0.3051Yes
146SPBC25SPBC25
Entrez,  Source
spindle pole body component 25 homolog (S. cerevisiae)13182-0.282-0.2801Yes
147SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113215-0.309-0.2551Yes
148PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513230-0.326-0.2272Yes
149GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 113239-0.335-0.1980Yes
150CCND1CCND1
Entrez,  Source
cyclin D113250-0.352-0.1675Yes
151PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha13298-0.461-0.1301Yes
152SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 113308-0.484-0.0877Yes
153CTGFCTGF
Entrez,  Source
connective tissue growth factor13313-0.503-0.0433Yes
154F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)13315-0.5110.0020Yes
Table: GSEA details [plain text format]



Fig 2: UVC_TTD_ALL_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVC_TTD_ALL_DN: Random ES distribution   
Gene set null distribution of ES for UVC_TTD_ALL_DN