Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | UVC_XPCS_4HR_DN |
| Enrichment Score (ES) | -0.49548125 |
| Normalized Enrichment Score (NES) | -1.8228977 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.037888933 |
| FWER p-Value | 0.936 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | WNT5A | WNT5A Entrez, Source | wingless-type MMTV integration site family, member 5A | 696 | 0.112 | -0.0350 | No |
| 2 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 766 | 0.108 | -0.0232 | No |
| 3 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 960 | 0.099 | -0.0223 | No |
| 4 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 1240 | 0.088 | -0.0295 | No |
| 5 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 1285 | 0.086 | -0.0193 | No |
| 6 | GLRB | GLRB Entrez, Source | glycine receptor, beta | 1617 | 0.077 | -0.0323 | No |
| 7 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1682 | 0.075 | -0.0254 | No |
| 8 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.0305 | No |
| 9 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 2046 | 0.067 | -0.0313 | No |
| 10 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 2673 | 0.056 | -0.0698 | No |
| 11 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | -0.0622 | No |
| 12 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 3179 | 0.048 | -0.0918 | No |
| 13 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 3748 | 0.040 | -0.1284 | No |
| 14 | EDD1 | EDD1 Entrez, Source | E3 ubiquitin protein ligase, HECT domain containing, 1 | 3754 | 0.040 | -0.1225 | No |
| 15 | AKAP9 | AKAP9 Entrez, Source | A kinase (PRKA) anchor protein (yotiao) 9 | 3978 | 0.037 | -0.1336 | No |
| 16 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 4160 | 0.034 | -0.1419 | No |
| 17 | RSN | RSN Entrez, Source | restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) | 4173 | 0.034 | -0.1375 | No |
| 18 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 4336 | 0.032 | -0.1447 | No |
| 19 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 4587 | 0.029 | -0.1590 | No |
| 20 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 4598 | 0.029 | -0.1553 | No |
| 21 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4743 | 0.027 | -0.1619 | No |
| 22 | PTPN12 | PTPN12 Entrez, Source | protein tyrosine phosphatase, non-receptor type 12 | 5000 | 0.024 | -0.1775 | No |
| 23 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 5047 | 0.023 | -0.1773 | No |
| 24 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 5072 | 0.023 | -0.1756 | No |
| 25 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 5085 | 0.023 | -0.1729 | No |
| 26 | AFAP | AFAP Entrez, Source | - | 5277 | 0.021 | -0.1841 | No |
| 27 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 5318 | 0.020 | -0.1839 | No |
| 28 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | -0.1834 | No |
| 29 | MECP2 | MECP2 Entrez, Source | methyl CpG binding protein 2 (Rett syndrome) | 5444 | 0.019 | -0.1873 | No |
| 30 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 5810 | 0.015 | -0.2125 | No |
| 31 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 5955 | 0.013 | -0.2213 | No |
| 32 | ZHX3 | ZHX3 Entrez, Source | zinc fingers and homeoboxes 3 | 5985 | 0.013 | -0.2215 | No |
| 33 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 6045 | 0.012 | -0.2240 | No |
| 34 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 6064 | 0.012 | -0.2234 | No |
| 35 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 6186 | 0.011 | -0.2308 | No |
| 36 | PARG | PARG Entrez, Source | poly (ADP-ribose) glycohydrolase | 6188 | 0.011 | -0.2292 | No |
| 37 | RBM16 | RBM16 Entrez, Source | RNA binding motif protein 16 | 6416 | 0.008 | -0.2450 | No |
| 38 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 6449 | 0.008 | -0.2461 | No |
| 39 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 6692 | 0.006 | -0.2635 | No |
| 40 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 6751 | 0.005 | -0.2672 | No |
| 41 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 6781 | 0.004 | -0.2687 | No |
| 42 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.2743 | No |
| 43 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 6964 | 0.002 | -0.2814 | No |
| 44 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 6986 | 0.002 | -0.2827 | No |
| 45 | TRIO | TRIO Entrez, Source | triple functional domain (PTPRF interacting) | 6995 | 0.002 | -0.2830 | No |
| 46 | RBM39 | RBM39 Entrez, Source | RNA binding motif protein 39 | 7326 | -0.002 | -0.3077 | No |
| 47 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 7463 | -0.003 | -0.3174 | No |
| 48 | KLF6 | KLF6 Entrez, Source | Kruppel-like factor 6 | 7545 | -0.004 | -0.3229 | No |
| 49 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 7619 | -0.005 | -0.3276 | No |
| 50 | CENTB2 | CENTB2 Entrez, Source | centaurin, beta 2 | 7774 | -0.007 | -0.3382 | No |
| 51 | PRR3 | PRR3 Entrez, Source | proline rich 3 | 7791 | -0.007 | -0.3383 | No |
| 52 | CEP350 | CEP350 Entrez, Source | centrosomal protein 350kDa | 7828 | -0.007 | -0.3399 | No |
| 53 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 7838 | -0.008 | -0.3394 | No |
| 54 | CNOT2 | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 7845 | -0.008 | -0.3386 | No |
| 55 | ATF2 | ATF2 Entrez, Source | activating transcription factor 2 | 7856 | -0.008 | -0.3381 | No |
| 56 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 8159 | -0.011 | -0.3592 | No |
| 57 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 8325 | -0.013 | -0.3696 | No |
| 58 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 8474 | -0.015 | -0.3784 | No |
| 59 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 8616 | -0.017 | -0.3863 | No |
| 60 | E2F5 | E2F5 Entrez, Source | E2F transcription factor 5, p130-binding | 8663 | -0.018 | -0.3870 | No |
| 61 | PUM2 | PUM2 Entrez, Source | pumilio homolog 2 (Drosophila) | 8893 | -0.020 | -0.4011 | No |
| 62 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 9017 | -0.022 | -0.4070 | No |
| 63 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 9145 | -0.024 | -0.4129 | No |
| 64 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 9194 | -0.024 | -0.4127 | No |
| 65 | BMPR1A | BMPR1A Entrez, Source | bone morphogenetic protein receptor, type IA | 9300 | -0.026 | -0.4165 | No |
| 66 | SOS2 | SOS2 Entrez, Source | son of sevenless homolog 2 (Drosophila) | 9696 | -0.032 | -0.4413 | No |
| 67 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 10173 | -0.039 | -0.4711 | No |
| 68 | MTF2 | MTF2 Entrez, Source | metal response element binding transcription factor 2 | 10194 | -0.040 | -0.4664 | No |
| 69 | BTRC | BTRC Entrez, Source | beta-transducin repeat containing | 10328 | -0.042 | -0.4698 | No |
| 70 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 10375 | -0.043 | -0.4666 | No |
| 71 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 10642 | -0.048 | -0.4792 | No |
| 72 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 10736 | -0.050 | -0.4783 | No |
| 73 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 10930 | -0.054 | -0.4844 | No |
| 74 | CNOT4 | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 11078 | -0.058 | -0.4865 | Yes |
| 75 | STRN3 | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 11105 | -0.058 | -0.4793 | Yes |
| 76 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 11148 | -0.059 | -0.4732 | Yes |
| 77 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 11238 | -0.061 | -0.4704 | Yes |
| 78 | ZNF292 | ZNF292 Entrez, Source | zinc finger protein 292 | 11534 | -0.070 | -0.4818 | Yes |
| 79 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 11596 | -0.072 | -0.4752 | Yes |
| 80 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 11687 | -0.075 | -0.4702 | Yes |
| 81 | MTMR3 | MTMR3 Entrez, Source | myotubularin related protein 3 | 11869 | -0.082 | -0.4711 | Yes |
| 82 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 11872 | -0.082 | -0.4584 | Yes |
| 83 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 11999 | -0.087 | -0.4543 | Yes |
| 84 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12079 | -0.091 | -0.4461 | Yes |
| 85 | CEP170 | CEP170 Entrez, Source | centrosomal protein 170kDa | 12151 | -0.094 | -0.4367 | Yes |
| 86 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 12549 | -0.121 | -0.4476 | Yes |
| 87 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12557 | -0.122 | -0.4291 | Yes |
| 88 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 12603 | -0.125 | -0.4128 | Yes |
| 89 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 12665 | -0.131 | -0.3969 | Yes |
| 90 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 12733 | -0.139 | -0.3802 | Yes |
| 91 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12771 | -0.144 | -0.3604 | Yes |
| 92 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 12840 | -0.154 | -0.3414 | Yes |
| 93 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 13105 | -0.234 | -0.3247 | Yes |
| 94 | RRAS2 | RRAS2 Entrez, Source | related RAS viral (r-ras) oncogene homolog 2 | 13125 | -0.244 | -0.2879 | Yes |
| 95 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13180 | -0.281 | -0.2480 | Yes |
| 96 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13215 | -0.309 | -0.2021 | Yes |
| 97 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13239 | -0.335 | -0.1513 | Yes |
| 98 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13313 | -0.503 | -0.0780 | Yes |
| 99 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13315 | -0.511 | 0.0020 | Yes |
