Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$CP2_02 |
| Enrichment Score (ES) | -0.46317545 |
| Normalized Enrichment Score (NES) | -1.6893913 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.070989214 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 134 | 0.198 | 0.0154 | No |
| 2 | CNTN6 | CNTN6 Entrez, Source | contactin 6 | 177 | 0.181 | 0.0356 | No |
| 3 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 181 | 0.178 | 0.0584 | No |
| 4 | GPC3 | GPC3 Entrez, Source | glypican 3 | 221 | 0.167 | 0.0770 | No |
| 5 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 265 | 0.156 | 0.0938 | No |
| 6 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 471 | 0.128 | 0.0948 | No |
| 7 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 808 | 0.106 | 0.0831 | No |
| 8 | EFNA3 | EFNA3 Entrez, Source | ephrin-A3 | 1075 | 0.094 | 0.0752 | No |
| 9 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 1330 | 0.085 | 0.0670 | No |
| 10 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1428 | 0.082 | 0.0702 | No |
| 11 | GRB7 | GRB7 Entrez, Source | growth factor receptor-bound protein 7 | 1701 | 0.074 | 0.0592 | No |
| 12 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1727 | 0.074 | 0.0668 | No |
| 13 | MAPRE3 | MAPRE3 Entrez, Source | microtubule-associated protein, RP/EB family, member 3 | 1919 | 0.070 | 0.0614 | No |
| 14 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 1971 | 0.069 | 0.0664 | No |
| 15 | AQP6 | AQP6 Entrez, Source | aquaporin 6, kidney specific | 2012 | 0.068 | 0.0721 | No |
| 16 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2033 | 0.067 | 0.0793 | No |
| 17 | BTBD14B | BTBD14B Entrez, Source | BTB (POZ) domain containing 14B | 2264 | 0.063 | 0.0700 | No |
| 18 | RGS8 | RGS8 Entrez, Source | regulator of G-protein signalling 8 | 2585 | 0.057 | 0.0532 | No |
| 19 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 2654 | 0.056 | 0.0553 | No |
| 20 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 2925 | 0.051 | 0.0415 | No |
| 21 | FGF9 | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 3315 | 0.046 | 0.0181 | No |
| 22 | LHX2 | LHX2 Entrez, Source | LIM homeobox 2 | 3378 | 0.045 | 0.0191 | No |
| 23 | KCNC2 | KCNC2 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 2 | 3455 | 0.044 | 0.0190 | No |
| 24 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 3666 | 0.041 | 0.0084 | No |
| 25 | ARHGAP5 | ARHGAP5 Entrez, Source | Rho GTPase activating protein 5 | 3833 | 0.039 | 0.0009 | No |
| 26 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 3836 | 0.039 | 0.0058 | No |
| 27 | EPN3 | EPN3 Entrez, Source | epsin 3 | 3858 | 0.039 | 0.0092 | No |
| 28 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 3971 | 0.037 | 0.0054 | No |
| 29 | KCNE3 | KCNE3 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 3 | 4233 | 0.033 | -0.0100 | No |
| 30 | PTHLH | PTHLH Entrez, Source | parathyroid hormone-like hormone | 4263 | 0.033 | -0.0079 | No |
| 31 | ADNP | ADNP Entrez, Source | activity-dependent neuroprotector | 4421 | 0.031 | -0.0158 | No |
| 32 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 4499 | 0.030 | -0.0177 | No |
| 33 | DHH | DHH Entrez, Source | desert hedgehog homolog (Drosophila) | 4887 | 0.025 | -0.0436 | No |
| 34 | CAPN6 | CAPN6 Entrez, Source | calpain 6 | 5151 | 0.022 | -0.0607 | No |
| 35 | CITED1 | CITED1 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 5242 | 0.021 | -0.0648 | No |
| 36 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 5318 | 0.020 | -0.0678 | No |
| 37 | GNB3 | GNB3 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 5681 | 0.016 | -0.0930 | No |
| 38 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6058 | 0.012 | -0.1199 | No |
| 39 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 6529 | 0.007 | -0.1544 | No |
| 40 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 6539 | 0.007 | -0.1542 | No |
| 41 | RPL41 | RPL41 Entrez, Source | ribosomal protein L41 | 6583 | 0.007 | -0.1565 | No |
| 42 | C1QTNF5 | C1QTNF5 Entrez, Source | C1q and tumor necrosis factor related protein 5 | 6763 | 0.005 | -0.1695 | No |
| 43 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 6781 | 0.004 | -0.1702 | No |
| 44 | RAB10 | RAB10 Entrez, Source | RAB10, member RAS oncogene family | 7106 | 0.001 | -0.1945 | No |
| 45 | RYR1 | RYR1 Entrez, Source | ryanodine receptor 1 (skeletal) | 7158 | 0.000 | -0.1983 | No |
| 46 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 7242 | -0.001 | -0.2045 | No |
| 47 | FEV | FEV Entrez, Source | FEV (ETS oncogene family) | 7265 | -0.001 | -0.2061 | No |
| 48 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 7333 | -0.002 | -0.2109 | No |
| 49 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 7356 | -0.002 | -0.2123 | No |
| 50 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 7525 | -0.004 | -0.2244 | No |
| 51 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 7596 | -0.005 | -0.2291 | No |
| 52 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 7799 | -0.007 | -0.2434 | No |
| 53 | CS | CS Entrez, Source | citrate synthase | 7918 | -0.009 | -0.2513 | No |
| 54 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 7947 | -0.009 | -0.2522 | No |
| 55 | XPNPEP1 | XPNPEP1 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 8376 | -0.014 | -0.2827 | No |
| 56 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 8843 | -0.020 | -0.3154 | No |
| 57 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 9017 | -0.022 | -0.3256 | No |
| 58 | NTRK3 | NTRK3 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 3 | 9078 | -0.023 | -0.3272 | No |
| 59 | PRKACA | PRKACA Entrez, Source | protein kinase, cAMP-dependent, catalytic, alpha | 9115 | -0.023 | -0.3269 | No |
| 60 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 9143 | -0.024 | -0.3259 | No |
| 61 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 9159 | -0.024 | -0.3239 | No |
| 62 | NNAT | NNAT Entrez, Source | neuronatin | 9178 | -0.024 | -0.3222 | No |
| 63 | CAMK2G | CAMK2G Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma | 9218 | -0.025 | -0.3219 | No |
| 64 | ADRA1A | ADRA1A Entrez, Source | adrenergic, alpha-1A-, receptor | 9363 | -0.027 | -0.3293 | No |
| 65 | RASSF1 | RASSF1 Entrez, Source | Ras association (RalGDS/AF-6) domain family 1 | 9841 | -0.034 | -0.3610 | No |
| 66 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 10537 | -0.046 | -0.4076 | No |
| 67 | TLN1 | TLN1 Entrez, Source | talin 1 | 10840 | -0.052 | -0.4236 | No |
| 68 | NISCH | NISCH Entrez, Source | nischarin | 10900 | -0.054 | -0.4211 | No |
| 69 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 11170 | -0.060 | -0.4338 | No |
| 70 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 11338 | -0.063 | -0.4382 | No |
| 71 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11670 | -0.074 | -0.4536 | Yes |
| 72 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 11741 | -0.077 | -0.4490 | Yes |
| 73 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 11774 | -0.078 | -0.4413 | Yes |
| 74 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 11968 | -0.086 | -0.4449 | Yes |
| 75 | SCAMP5 | SCAMP5 Entrez, Source | secretory carrier membrane protein 5 | 12017 | -0.088 | -0.4372 | Yes |
| 76 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12083 | -0.091 | -0.4303 | Yes |
| 77 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 12175 | -0.096 | -0.4249 | Yes |
| 78 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12330 | -0.106 | -0.4229 | Yes |
| 79 | HPCAL1 | HPCAL1 Entrez, Source | hippocalcin-like 1 | 12394 | -0.111 | -0.4134 | Yes |
| 80 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12424 | -0.112 | -0.4011 | Yes |
| 81 | RHBDF1 | RHBDF1 Entrez, Source | rhomboid 5 homolog 1 (Drosophila) | 12464 | -0.115 | -0.3892 | Yes |
| 82 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12489 | -0.117 | -0.3760 | Yes |
| 83 | FLOT2 | FLOT2 Entrez, Source | flotillin 2 | 12500 | -0.117 | -0.3617 | Yes |
| 84 | GPRC5C | GPRC5C Entrez, Source | G protein-coupled receptor, family C, group 5, member C | 12581 | -0.124 | -0.3517 | Yes |
| 85 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.3417 | Yes |
| 86 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12735 | -0.139 | -0.3283 | Yes |
| 87 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12748 | -0.141 | -0.3111 | Yes |
| 88 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12850 | -0.156 | -0.2986 | Yes |
| 89 | CLDN4 | CLDN4 Entrez, Source | claudin 4 | 12969 | -0.181 | -0.2842 | Yes |
| 90 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 12970 | -0.181 | -0.2610 | Yes |
| 91 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13078 | -0.223 | -0.2404 | Yes |
| 92 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13212 | -0.305 | -0.2111 | Yes |
| 93 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 13240 | -0.338 | -0.1695 | Yes |
| 94 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13286 | -0.422 | -0.1186 | Yes |
| 95 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.0589 | Yes |
| 96 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13307 | -0.479 | 0.0026 | Yes |
