Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$E2F1_Q6 |
| Enrichment Score (ES) | -0.46403322 |
| Normalized Enrichment Score (NES) | -1.7136017 |
| Nominal p-value | 0.0015128592 |
| FDR q-value | 0.061356686 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 219 | 0.169 | 0.0073 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 314 | 0.148 | 0.0212 | No |
| 3 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 990 | 0.098 | -0.0159 | No |
| 4 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 1264 | 0.087 | -0.0242 | No |
| 5 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 1335 | 0.085 | -0.0175 | No |
| 6 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 1353 | 0.084 | -0.0069 | No |
| 7 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 1387 | 0.083 | 0.0024 | No |
| 8 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 1393 | 0.083 | 0.0137 | No |
| 9 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 1459 | 0.081 | 0.0203 | No |
| 10 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 1799 | 0.072 | 0.0049 | No |
| 11 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | 0.0075 | No |
| 12 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | 0.0146 | No |
| 13 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 2081 | 0.066 | 0.0129 | No |
| 14 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 2374 | 0.061 | -0.0005 | No |
| 15 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 2381 | 0.061 | 0.0076 | No |
| 16 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 2402 | 0.060 | 0.0146 | No |
| 17 | KCNS2 | KCNS2 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 | 2806 | 0.053 | -0.0083 | No |
| 18 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3021 | 0.050 | -0.0174 | No |
| 19 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 3100 | 0.049 | -0.0164 | No |
| 20 | NCL | NCL Entrez, Source | nucleolin | 3112 | 0.049 | -0.0103 | No |
| 21 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 3549 | 0.042 | -0.0373 | No |
| 22 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 3551 | 0.042 | -0.0314 | No |
| 23 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 3799 | 0.039 | -0.0444 | No |
| 24 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.0743 | No |
| 25 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4340 | 0.032 | -0.0759 | No |
| 26 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 4580 | 0.029 | -0.0898 | No |
| 27 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 4779 | 0.027 | -0.1010 | No |
| 28 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.1034 | No |
| 29 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5142 | 0.022 | -0.1215 | No |
| 30 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 5147 | 0.022 | -0.1187 | No |
| 31 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 5173 | 0.022 | -0.1175 | No |
| 32 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 5319 | 0.020 | -0.1256 | No |
| 33 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 5474 | 0.019 | -0.1346 | No |
| 34 | GATA1 | GATA1 Entrez, Source | GATA binding protein 1 (globin transcription factor 1) | 5500 | 0.018 | -0.1339 | No |
| 35 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 5645 | 0.017 | -0.1424 | No |
| 36 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5784 | 0.015 | -0.1506 | No |
| 37 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 5981 | 0.013 | -0.1636 | No |
| 38 | HTF9C | HTF9C Entrez, Source | - | 6047 | 0.012 | -0.1668 | No |
| 39 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6204 | 0.011 | -0.1770 | No |
| 40 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 6598 | 0.006 | -0.2057 | No |
| 41 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 6925 | 0.003 | -0.2299 | No |
| 42 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 7569 | -0.005 | -0.2778 | No |
| 43 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 7657 | -0.005 | -0.2836 | No |
| 44 | CORT | CORT Entrez, Source | cortistatin | 7765 | -0.007 | -0.2908 | No |
| 45 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 8243 | -0.012 | -0.3250 | No |
| 46 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8337 | -0.013 | -0.3301 | No |
| 47 | XTP3TPA | XTP3TPA Entrez, Source | - | 8400 | -0.014 | -0.3328 | No |
| 48 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8763 | -0.019 | -0.3574 | No |
| 49 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 8801 | -0.019 | -0.3575 | No |
| 50 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 9198 | -0.024 | -0.3839 | No |
| 51 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9359 | -0.027 | -0.3922 | No |
| 52 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 9580 | -0.030 | -0.4046 | No |
| 53 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 9614 | -0.031 | -0.4027 | No |
| 54 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 10007 | -0.037 | -0.4271 | No |
| 55 | DCK | DCK Entrez, Source | deoxycytidine kinase | 10358 | -0.043 | -0.4475 | No |
| 56 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 10424 | -0.044 | -0.4462 | No |
| 57 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 10579 | -0.047 | -0.4512 | No |
| 58 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 10750 | -0.051 | -0.4569 | Yes |
| 59 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 10767 | -0.051 | -0.4509 | Yes |
| 60 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 10916 | -0.054 | -0.4544 | Yes |
| 61 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10985 | -0.056 | -0.4516 | Yes |
| 62 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 10993 | -0.056 | -0.4443 | Yes |
| 63 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11191 | -0.060 | -0.4507 | Yes |
| 64 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11206 | -0.060 | -0.4432 | Yes |
| 65 | TMPO | TMPO Entrez, Source | thymopoietin | 11294 | -0.062 | -0.4410 | Yes |
| 66 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 11574 | -0.071 | -0.4520 | Yes |
| 67 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 11604 | -0.072 | -0.4440 | Yes |
| 68 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11634 | -0.073 | -0.4358 | Yes |
| 69 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11780 | -0.078 | -0.4357 | Yes |
| 70 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 11803 | -0.079 | -0.4261 | Yes |
| 71 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 11898 | -0.083 | -0.4215 | Yes |
| 72 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11981 | -0.086 | -0.4155 | Yes |
| 73 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.4119 | Yes |
| 74 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 12137 | -0.093 | -0.4009 | Yes |
| 75 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 12233 | -0.099 | -0.3941 | Yes |
| 76 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12287 | -0.103 | -0.3836 | Yes |
| 77 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 12288 | -0.103 | -0.3691 | Yes |
| 78 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12409 | -0.112 | -0.3624 | Yes |
| 79 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12424 | -0.112 | -0.3475 | Yes |
| 80 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12486 | -0.117 | -0.3357 | Yes |
| 81 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 12692 | -0.134 | -0.3322 | Yes |
| 82 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 12724 | -0.138 | -0.3150 | Yes |
| 83 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 12807 | -0.149 | -0.3002 | Yes |
| 84 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12860 | -0.158 | -0.2818 | Yes |
| 85 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 13022 | -0.195 | -0.2663 | Yes |
| 86 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 13214 | -0.309 | -0.2371 | Yes |
| 87 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.1930 | Yes |
| 88 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | -0.1353 | Yes |
| 89 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.0694 | Yes |
| 90 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13316 | -0.512 | 0.0020 | Yes |
