Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$E2F_Q4_01 |
| Enrichment Score (ES) | -0.49072853 |
| Normalized Enrichment Score (NES) | -1.7809107 |
| Nominal p-value | 0.0015923567 |
| FDR q-value | 0.045939617 |
| FWER p-Value | 0.988 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 42 | 0.293 | 0.0401 | No |
| 2 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 810 | 0.106 | -0.0020 | No |
| 3 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 1393 | 0.083 | -0.0337 | No |
| 4 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 1630 | 0.076 | -0.0402 | No |
| 5 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 1676 | 0.075 | -0.0326 | No |
| 6 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 1799 | 0.072 | -0.0312 | No |
| 7 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.0281 | No |
| 8 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | -0.0206 | No |
| 9 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 2027 | 0.067 | -0.0176 | No |
| 10 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 2374 | 0.061 | -0.0348 | No |
| 11 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2958 | 0.051 | -0.0713 | No |
| 12 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 2977 | 0.050 | -0.0652 | No |
| 13 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 3017 | 0.050 | -0.0608 | No |
| 14 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3021 | 0.050 | -0.0537 | No |
| 15 | NCL | NCL Entrez, Source | nucleolin | 3112 | 0.049 | -0.0533 | No |
| 16 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 3222 | 0.047 | -0.0546 | No |
| 17 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 3648 | 0.041 | -0.0806 | No |
| 18 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 3919 | 0.038 | -0.0954 | No |
| 19 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 3943 | 0.037 | -0.0917 | No |
| 20 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3952 | 0.037 | -0.0868 | No |
| 21 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4151 | 0.034 | -0.0967 | No |
| 22 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.0998 | No |
| 23 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4340 | 0.032 | -0.1011 | No |
| 24 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.1365 | No |
| 25 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 4930 | 0.025 | -0.1381 | No |
| 26 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 4947 | 0.025 | -0.1357 | No |
| 27 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 5107 | 0.023 | -0.1443 | No |
| 28 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 5173 | 0.022 | -0.1460 | No |
| 29 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 5297 | 0.020 | -0.1523 | No |
| 30 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 5607 | 0.017 | -0.1731 | No |
| 31 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 5645 | 0.017 | -0.1734 | No |
| 32 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5882 | 0.014 | -0.1892 | No |
| 33 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 5996 | 0.013 | -0.1958 | No |
| 34 | HTF9C | HTF9C Entrez, Source | - | 6047 | 0.012 | -0.1978 | No |
| 35 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 6064 | 0.012 | -0.1972 | No |
| 36 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6197 | 0.011 | -0.2055 | No |
| 37 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6202 | 0.011 | -0.2042 | No |
| 38 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 6871 | 0.003 | -0.2541 | No |
| 39 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 7644 | -0.005 | -0.3115 | No |
| 40 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 7722 | -0.006 | -0.3165 | No |
| 41 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 7848 | -0.008 | -0.3248 | No |
| 42 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 7922 | -0.009 | -0.3290 | No |
| 43 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 7947 | -0.009 | -0.3295 | No |
| 44 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 8008 | -0.010 | -0.3326 | No |
| 45 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 8243 | -0.012 | -0.3485 | No |
| 46 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8337 | -0.013 | -0.3535 | No |
| 47 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8369 | -0.014 | -0.3538 | No |
| 48 | XTP3TPA | XTP3TPA Entrez, Source | - | 8400 | -0.014 | -0.3540 | No |
| 49 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 8601 | -0.017 | -0.3665 | No |
| 50 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8710 | -0.018 | -0.3720 | No |
| 51 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8763 | -0.019 | -0.3732 | No |
| 52 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 8801 | -0.019 | -0.3731 | No |
| 53 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 9305 | -0.026 | -0.4072 | No |
| 54 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9359 | -0.027 | -0.4073 | No |
| 55 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 9682 | -0.032 | -0.4269 | No |
| 56 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 10007 | -0.037 | -0.4459 | No |
| 57 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 10078 | -0.038 | -0.4456 | No |
| 58 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 10188 | -0.040 | -0.4479 | No |
| 59 | DCK | DCK Entrez, Source | deoxycytidine kinase | 10358 | -0.043 | -0.4544 | No |
| 60 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10535 | -0.046 | -0.4609 | No |
| 61 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 10579 | -0.047 | -0.4573 | No |
| 62 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10913 | -0.054 | -0.4744 | No |
| 63 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 10916 | -0.054 | -0.4666 | No |
| 64 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10950 | -0.055 | -0.4610 | No |
| 65 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 10996 | -0.056 | -0.4561 | No |
| 66 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 11190 | -0.060 | -0.4618 | No |
| 67 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 11574 | -0.071 | -0.4802 | Yes |
| 68 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11634 | -0.073 | -0.4739 | Yes |
| 69 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11780 | -0.078 | -0.4733 | Yes |
| 70 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 11803 | -0.079 | -0.4633 | Yes |
| 71 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11981 | -0.086 | -0.4639 | Yes |
| 72 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12091 | -0.091 | -0.4587 | Yes |
| 73 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.4462 | Yes |
| 74 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 12127 | -0.093 | -0.4340 | Yes |
| 75 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12409 | -0.112 | -0.4387 | Yes |
| 76 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12415 | -0.112 | -0.4226 | Yes |
| 77 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 12513 | -0.118 | -0.4124 | Yes |
| 78 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12774 | -0.145 | -0.4107 | Yes |
| 79 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12860 | -0.158 | -0.3939 | Yes |
| 80 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12946 | -0.175 | -0.3745 | Yes |
| 81 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 13022 | -0.195 | -0.3513 | Yes |
| 82 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.3198 | Yes |
| 83 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.2727 | Yes |
| 84 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | -0.2118 | Yes |
| 85 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.1429 | Yes |
| 86 | DIO3 | DIO3 Entrez, Source | deiodinase, iodothyronine, type III | 13306 | -0.477 | -0.0729 | Yes |
| 87 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13316 | -0.512 | 0.0020 | Yes |
