Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$E2F_Q6_01 |
| Enrichment Score (ES) | -0.54218394 |
| Normalized Enrichment Score (NES) | -1.9333267 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.016397143 |
| FWER p-Value | 0.483 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 1387 | 0.083 | -0.0910 | No |
| 2 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 1393 | 0.083 | -0.0779 | No |
| 3 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 1676 | 0.075 | -0.0869 | No |
| 4 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 1799 | 0.072 | -0.0844 | No |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.0802 | No |
| 6 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | -0.0716 | No |
| 7 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 2027 | 0.067 | -0.0675 | No |
| 8 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 2374 | 0.061 | -0.0837 | No |
| 9 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2958 | 0.051 | -0.1194 | No |
| 10 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 2977 | 0.050 | -0.1126 | No |
| 11 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 3017 | 0.050 | -0.1074 | No |
| 12 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 3021 | 0.050 | -0.0995 | No |
| 13 | NCL | NCL Entrez, Source | nucleolin | 3112 | 0.049 | -0.0984 | No |
| 14 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3952 | 0.037 | -0.1556 | No |
| 15 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4151 | 0.034 | -0.1649 | No |
| 16 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.1675 | No |
| 17 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4340 | 0.032 | -0.1684 | No |
| 18 | SNCB | SNCB Entrez, Source | synuclein, beta | 4601 | 0.029 | -0.1833 | No |
| 19 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.1986 | No |
| 20 | HTR2C | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C | 5015 | 0.024 | -0.2063 | No |
| 21 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 5107 | 0.023 | -0.2095 | No |
| 22 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 5173 | 0.022 | -0.2108 | No |
| 23 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 5297 | 0.020 | -0.2168 | No |
| 24 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 5645 | 0.017 | -0.2403 | No |
| 25 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.2496 | No |
| 26 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5882 | 0.014 | -0.2532 | No |
| 27 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 5996 | 0.013 | -0.2597 | No |
| 28 | HTF9C | HTF9C Entrez, Source | - | 6047 | 0.012 | -0.2614 | No |
| 29 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 6064 | 0.012 | -0.2606 | No |
| 30 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6197 | 0.011 | -0.2688 | No |
| 31 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6202 | 0.011 | -0.2673 | No |
| 32 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 6871 | 0.003 | -0.3172 | No |
| 33 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 6925 | 0.003 | -0.3207 | No |
| 34 | SIAHBP1 | SIAHBP1 Entrez, Source | - | 7243 | -0.001 | -0.3445 | No |
| 35 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 7718 | -0.006 | -0.3793 | No |
| 36 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 7722 | -0.006 | -0.3785 | No |
| 37 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 7848 | -0.008 | -0.3867 | No |
| 38 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 7922 | -0.009 | -0.3908 | No |
| 39 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 7947 | -0.009 | -0.3911 | No |
| 40 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 8008 | -0.010 | -0.3941 | No |
| 41 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 8243 | -0.012 | -0.4097 | No |
| 42 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 8283 | -0.013 | -0.4106 | No |
| 43 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8337 | -0.013 | -0.4124 | No |
| 44 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8369 | -0.014 | -0.4125 | No |
| 45 | XTP3TPA | XTP3TPA Entrez, Source | - | 8400 | -0.014 | -0.4124 | No |
| 46 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 8601 | -0.017 | -0.4247 | No |
| 47 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8710 | -0.018 | -0.4299 | No |
| 48 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8763 | -0.019 | -0.4308 | No |
| 49 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 8801 | -0.019 | -0.4304 | No |
| 50 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 9305 | -0.026 | -0.4641 | No |
| 51 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9427 | -0.028 | -0.4687 | No |
| 52 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 9476 | -0.029 | -0.4677 | No |
| 53 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 9682 | -0.032 | -0.4779 | No |
| 54 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 10078 | -0.038 | -0.5015 | No |
| 55 | DCK | DCK Entrez, Source | deoxycytidine kinase | 10358 | -0.043 | -0.5156 | No |
| 56 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10535 | -0.046 | -0.5214 | No |
| 57 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 10579 | -0.047 | -0.5171 | No |
| 58 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10913 | -0.054 | -0.5333 | Yes |
| 59 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 10916 | -0.054 | -0.5246 | Yes |
| 60 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10950 | -0.055 | -0.5182 | Yes |
| 61 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10985 | -0.056 | -0.5117 | Yes |
| 62 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 10996 | -0.056 | -0.5033 | Yes |
| 63 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 11338 | -0.063 | -0.5186 | Yes |
| 64 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11634 | -0.073 | -0.5289 | Yes |
| 65 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 11779 | -0.078 | -0.5270 | Yes |
| 66 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11780 | -0.078 | -0.5143 | Yes |
| 67 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 11803 | -0.079 | -0.5030 | Yes |
| 68 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11981 | -0.086 | -0.5023 | Yes |
| 69 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12091 | -0.091 | -0.4956 | Yes |
| 70 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.4817 | Yes |
| 71 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 12127 | -0.093 | -0.4680 | Yes |
| 72 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12330 | -0.106 | -0.4660 | Yes |
| 73 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12409 | -0.112 | -0.4536 | Yes |
| 74 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12415 | -0.112 | -0.4357 | Yes |
| 75 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12424 | -0.112 | -0.4180 | Yes |
| 76 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12525 | -0.119 | -0.4060 | Yes |
| 77 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12557 | -0.122 | -0.3885 | Yes |
| 78 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12774 | -0.145 | -0.3811 | Yes |
| 79 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12860 | -0.158 | -0.3618 | Yes |
| 80 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12946 | -0.175 | -0.3397 | Yes |
| 81 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 13022 | -0.195 | -0.3134 | Yes |
| 82 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.2770 | Yes |
| 83 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.2247 | Yes |
| 84 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | -0.1568 | Yes |
| 85 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.0806 | Yes |
| 86 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13316 | -0.512 | 0.0020 | Yes |
