Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$FXR_IR1_Q6 |
| Enrichment Score (ES) | -0.55962944 |
| Normalized Enrichment Score (NES) | -1.8659004 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.027404023 |
| FWER p-Value | 0.793 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 616 | 0.117 | -0.0190 | No |
| 2 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 1028 | 0.096 | -0.0275 | No |
| 3 | ABCB11 | ABCB11 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 1369 | 0.083 | -0.0337 | No |
| 4 | NDRG2 | NDRG2 Entrez, Source | NDRG family member 2 | 1456 | 0.081 | -0.0213 | No |
| 5 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 1732 | 0.074 | -0.0249 | No |
| 6 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 1883 | 0.070 | -0.0197 | No |
| 7 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | -0.0073 | No |
| 8 | FABP6 | FABP6 Entrez, Source | fatty acid binding protein 6, ileal (gastrotropin) | 2100 | 0.066 | -0.0043 | No |
| 9 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 2194 | 0.064 | 0.0036 | No |
| 10 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 2896 | 0.052 | -0.0371 | No |
| 11 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 3122 | 0.048 | -0.0427 | No |
| 12 | GRIK3 | GRIK3 Entrez, Source | glutamate receptor, ionotropic, kainate 3 | 3319 | 0.046 | -0.0469 | No |
| 13 | SLC13A5 | SLC13A5 Entrez, Source | solute carrier family 13 (sodium-dependent citrate transporter), member 5 | 3488 | 0.043 | -0.0494 | No |
| 14 | MRPS18B | MRPS18B Entrez, Source | mitochondrial ribosomal protein S18B | 4053 | 0.036 | -0.0836 | No |
| 15 | GPR12 | GPR12 Entrez, Source | G protein-coupled receptor 12 | 4604 | 0.029 | -0.1183 | No |
| 16 | KLHL13 | KLHL13 Entrez, Source | kelch-like 13 (Drosophila) | 4760 | 0.027 | -0.1237 | No |
| 17 | RAB3C | RAB3C Entrez, Source | RAB3C, member RAS oncogene family | 4837 | 0.026 | -0.1234 | No |
| 18 | VAMP1 | VAMP1 Entrez, Source | vesicle-associated membrane protein 1 (synaptobrevin 1) | 4878 | 0.025 | -0.1205 | No |
| 19 | PPP2R2B | PPP2R2B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 4958 | 0.024 | -0.1208 | No |
| 20 | CENTG1 | CENTG1 Entrez, Source | centaurin, gamma 1 | 4982 | 0.024 | -0.1169 | No |
| 21 | EIF5 | EIF5 Entrez, Source | eukaryotic translation initiation factor 5 | 4995 | 0.024 | -0.1122 | No |
| 22 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 5851 | 0.014 | -0.1732 | No |
| 23 | VAMP2 | VAMP2 Entrez, Source | vesicle-associated membrane protein 2 (synaptobrevin 2) | 5873 | 0.014 | -0.1715 | No |
| 24 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 6199 | 0.011 | -0.1934 | No |
| 25 | RNF14 | RNF14 Entrez, Source | ring finger protein 14 | 6277 | 0.010 | -0.1968 | No |
| 26 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 6751 | 0.005 | -0.2313 | No |
| 27 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6899 | 0.003 | -0.2417 | No |
| 28 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7012 | 0.002 | -0.2497 | No |
| 29 | TTC12 | TTC12 Entrez, Source | tetratricopeptide repeat domain 12 | 7968 | -0.009 | -0.3194 | No |
| 30 | GDNF | GDNF Entrez, Source | glial cell derived neurotrophic factor | 8466 | -0.015 | -0.3533 | No |
| 31 | TTL | TTL Entrez, Source | tubulin tyrosine ligase | 9272 | -0.026 | -0.4079 | No |
| 32 | LIMK2 | LIMK2 Entrez, Source | LIM domain kinase 2 | 9546 | -0.030 | -0.4215 | No |
| 33 | ST7 | ST7 Entrez, Source | suppression of tumorigenicity 7 | 9977 | -0.036 | -0.4454 | No |
| 34 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 10557 | -0.046 | -0.4782 | No |
| 35 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11131 | -0.059 | -0.5076 | No |
| 36 | ARF3 | ARF3 Entrez, Source | ADP-ribosylation factor 3 | 11823 | -0.080 | -0.5409 | Yes |
| 37 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 11831 | -0.081 | -0.5226 | Yes |
| 38 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 11851 | -0.081 | -0.5051 | Yes |
| 39 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 11968 | -0.086 | -0.4939 | Yes |
| 40 | SCAMP5 | SCAMP5 Entrez, Source | secretory carrier membrane protein 5 | 12017 | -0.088 | -0.4771 | Yes |
| 41 | PDC | PDC Entrez, Source | phosducin | 12144 | -0.094 | -0.4647 | Yes |
| 42 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 12374 | -0.109 | -0.4565 | Yes |
| 43 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12424 | -0.112 | -0.4340 | Yes |
| 44 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 12787 | -0.146 | -0.4272 | Yes |
| 45 | DLGAP4 | DLGAP4 Entrez, Source | discs, large (Drosophila) homolog-associated protein 4 | 12796 | -0.147 | -0.3935 | Yes |
| 46 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 12807 | -0.149 | -0.3596 | Yes |
| 47 | KITLG | KITLG Entrez, Source | KIT ligand | 12923 | -0.170 | -0.3286 | Yes |
| 48 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 12970 | -0.181 | -0.2899 | Yes |
| 49 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 13130 | -0.247 | -0.2443 | Yes |
| 50 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.1777 | Yes |
| 51 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.1030 | Yes |
| 52 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13307 | -0.479 | 0.0026 | Yes |
