Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$FXR_Q3 |
| Enrichment Score (ES) | 0.436941 |
| Normalized Enrichment Score (NES) | 1.5452161 |
| Nominal p-value | 0.022113021 |
| FDR q-value | 0.12407438 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 26 | 0.337 | 0.1079 | Yes |
| 2 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.1883 | Yes |
| 3 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 471 | 0.128 | 0.1996 | Yes |
| 4 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 503 | 0.125 | 0.2379 | Yes |
| 5 | PDE1A | PDE1A Entrez, Source | phosphodiesterase 1A, calmodulin-dependent | 701 | 0.112 | 0.2595 | Yes |
| 6 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 810 | 0.106 | 0.2860 | Yes |
| 7 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 1000 | 0.098 | 0.3036 | Yes |
| 8 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 1028 | 0.096 | 0.3329 | Yes |
| 9 | LMO3 | LMO3 Entrez, Source | LIM domain only 3 (rhombotin-like 2) | 1366 | 0.084 | 0.3348 | Yes |
| 10 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 1732 | 0.074 | 0.3313 | Yes |
| 11 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 1883 | 0.070 | 0.3429 | Yes |
| 12 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | 0.3618 | Yes |
| 13 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 2017 | 0.068 | 0.3777 | Yes |
| 14 | FABP6 | FABP6 Entrez, Source | fatty acid binding protein 6, ileal (gastrotropin) | 2100 | 0.066 | 0.3930 | Yes |
| 15 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 2122 | 0.065 | 0.4127 | Yes |
| 16 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 2513 | 0.058 | 0.4024 | Yes |
| 17 | LHX1 | LHX1 Entrez, Source | LIM homeobox 1 | 2531 | 0.058 | 0.4200 | Yes |
| 18 | GUCY2F | GUCY2F Entrez, Source | guanylate cyclase 2F, retinal | 2753 | 0.054 | 0.4210 | Yes |
| 19 | WDR20 | WDR20 Entrez, Source | WD repeat domain 20 | 3058 | 0.049 | 0.4142 | Yes |
| 20 | STOML2 | STOML2 Entrez, Source | stomatin (EPB72)-like 2 | 3084 | 0.049 | 0.4283 | Yes |
| 21 | GRIK3 | GRIK3 Entrez, Source | glutamate receptor, ionotropic, kainate 3 | 3319 | 0.046 | 0.4255 | Yes |
| 22 | ABCG4 | ABCG4 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 4 | 3363 | 0.045 | 0.4369 | Yes |
| 23 | OTP | OTP Entrez, Source | orthopedia homolog (Drosophila) | 4337 | 0.032 | 0.3743 | No |
| 24 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 4499 | 0.030 | 0.3719 | No |
| 25 | ITIH3 | ITIH3 Entrez, Source | inter-alpha (globulin) inhibitor H3 | 5229 | 0.021 | 0.3240 | No |
| 26 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 5445 | 0.019 | 0.3140 | No |
| 27 | OTX2 | OTX2 Entrez, Source | orthodenticle homolog 2 (Drosophila) | 5633 | 0.017 | 0.3054 | No |
| 28 | VAMP2 | VAMP2 Entrez, Source | vesicle-associated membrane protein 2 (synaptobrevin 2) | 5873 | 0.014 | 0.2920 | No |
| 29 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 5874 | 0.014 | 0.2966 | No |
| 30 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 6288 | 0.010 | 0.2688 | No |
| 31 | ATP5C1 | ATP5C1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 6499 | 0.008 | 0.2555 | No |
| 32 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 6513 | 0.007 | 0.2569 | No |
| 33 | FUT8 | FUT8 Entrez, Source | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 7725 | -0.006 | 0.1678 | No |
| 34 | ZIC1 | ZIC1 Entrez, Source | Zic family member 1 (odd-paired homolog, Drosophila) | 8976 | -0.022 | 0.0809 | No |
| 35 | NTRK3 | NTRK3 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 3 | 9078 | -0.023 | 0.0807 | No |
| 36 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 10897 | -0.054 | -0.0385 | No |
| 37 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 11576 | -0.071 | -0.0663 | No |
| 38 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 11776 | -0.078 | -0.0558 | No |
| 39 | EFEMP2 | EFEMP2 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 2 | 11825 | -0.080 | -0.0333 | No |
| 40 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 11831 | -0.081 | -0.0074 | No |
| 41 | MOS | MOS Entrez, Source | v-mos Moloney murine sarcoma viral oncogene homolog | 12201 | -0.097 | -0.0036 | No |
| 42 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12631 | -0.128 | 0.0058 | No |
| 43 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 12787 | -0.146 | 0.0417 | No |
