Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$HNF1_Q6 |
| Enrichment Score (ES) | 0.3541743 |
| Normalized Enrichment Score (NES) | 1.4743103 |
| Nominal p-value | 0.01910828 |
| FDR q-value | 0.16001877 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 26 | 0.337 | 0.0355 | Yes |
| 2 | AQP9 | AQP9 Entrez, Source | aquaporin 9 | 57 | 0.272 | 0.0634 | Yes |
| 3 | PLG | PLG Entrez, Source | plasminogen | 120 | 0.206 | 0.0816 | Yes |
| 4 | AFM | AFM Entrez, Source | afamin | 122 | 0.205 | 0.1043 | Yes |
| 5 | SGK2 | SGK2 Entrez, Source | serum/glucocorticoid regulated kinase 2 | 136 | 0.198 | 0.1253 | Yes |
| 6 | SI | SI Entrez, Source | sucrase-isomaltase (alpha-glucosidase) | 137 | 0.197 | 0.1472 | Yes |
| 7 | SERPINA7 | SERPINA7 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | 150 | 0.192 | 0.1676 | Yes |
| 8 | HNF4A | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 293 | 0.150 | 0.1736 | Yes |
| 9 | CART1 | CART1 Entrez, Source | cartilage paired-class homeoprotein 1 | 296 | 0.150 | 0.1901 | Yes |
| 10 | CSF3 | CSF3 Entrez, Source | colony stimulating factor 3 (granulocyte) | 359 | 0.141 | 0.2010 | Yes |
| 11 | NR1H4 | NR1H4 Entrez, Source | nuclear receptor subfamily 1, group H, member 4 | 390 | 0.137 | 0.2139 | Yes |
| 12 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 394 | 0.136 | 0.2288 | Yes |
| 13 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 459 | 0.129 | 0.2383 | Yes |
| 14 | FGB | FGB Entrez, Source | fibrinogen beta chain | 461 | 0.129 | 0.2525 | Yes |
| 15 | AFP | AFP Entrez, Source | alpha-fetoprotein | 470 | 0.128 | 0.2661 | Yes |
| 16 | OPRM1 | OPRM1 Entrez, Source | opioid receptor, mu 1 | 481 | 0.127 | 0.2794 | Yes |
| 17 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 546 | 0.122 | 0.2881 | Yes |
| 18 | APOM | APOM Entrez, Source | apolipoprotein M | 628 | 0.117 | 0.2949 | Yes |
| 19 | PRODH2 | PRODH2 Entrez, Source | proline dehydrogenase (oxidase) 2 | 708 | 0.111 | 0.3013 | Yes |
| 20 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 745 | 0.109 | 0.3107 | Yes |
| 21 | CDH16 | CDH16 Entrez, Source | cadherin 16, KSP-cadherin | 804 | 0.107 | 0.3182 | Yes |
| 22 | NTF3 | NTF3 Entrez, Source | neurotrophin 3 | 895 | 0.103 | 0.3227 | Yes |
| 23 | SOX18 | SOX18 Entrez, Source | SRY (sex determining region Y)-box 18 | 1001 | 0.097 | 0.3256 | Yes |
| 24 | POU3F2 | POU3F2 Entrez, Source | POU domain, class 3, transcription factor 2 | 1039 | 0.096 | 0.3335 | Yes |
| 25 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 1053 | 0.095 | 0.3430 | Yes |
| 26 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 1107 | 0.093 | 0.3493 | Yes |
| 27 | FGA | FGA Entrez, Source | fibrinogen alpha chain | 1253 | 0.088 | 0.3481 | Yes |
| 28 | HPN | HPN Entrez, Source | hepsin (transmembrane protease, serine 1) | 1303 | 0.086 | 0.3539 | Yes |
| 29 | FGFR4 | FGFR4 Entrez, Source | fibroblast growth factor receptor 4 | 1473 | 0.080 | 0.3501 | Yes |
| 30 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 1631 | 0.076 | 0.3467 | Yes |
| 31 | SERPINA4 | SERPINA4 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 | 1644 | 0.076 | 0.3542 | Yes |
| 32 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 1876 | 0.070 | 0.3445 | No |
| 33 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | 0.3479 | No |
| 34 | FXYD2 | FXYD2 Entrez, Source | FXYD domain containing ion transport regulator 2 | 2048 | 0.067 | 0.3468 | No |
| 35 | NAPSA | NAPSA Entrez, Source | napsin A aspartic peptidase | 2149 | 0.065 | 0.3464 | No |
| 36 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 2483 | 0.059 | 0.3278 | No |
| 37 | AGTR2 | AGTR2 Entrez, Source | angiotensin II receptor, type 2 | 2607 | 0.057 | 0.3248 | No |
| 38 | PLUNC | PLUNC Entrez, Source | palate, lung and nasal epithelium carcinoma associated | 2880 | 0.052 | 0.3100 | No |
| 39 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 2925 | 0.051 | 0.3124 | No |
| 40 | TCF12 | TCF12 Entrez, Source | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | 3016 | 0.050 | 0.3111 | No |
| 41 | GC | GC Entrez, Source | group-specific component (vitamin D binding protein) | 3034 | 0.050 | 0.3153 | No |
| 42 | DLX1 | DLX1 Entrez, Source | distal-less homeobox 1 | 3150 | 0.048 | 0.3119 | No |
| 43 | GUCA2B | GUCA2B Entrez, Source | guanylate cyclase activator 2B (uroguanylin) | 3325 | 0.045 | 0.3038 | No |
| 44 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 3570 | 0.042 | 0.2900 | No |
| 45 | CLOCK | CLOCK Entrez, Source | clock homolog (mouse) | 3722 | 0.040 | 0.2831 | No |
| 46 | HTR7 | HTR7 Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) | 3746 | 0.040 | 0.2858 | No |
| 47 | PNMA1 | PNMA1 Entrez, Source | paraneoplastic antigen MA1 | 3771 | 0.040 | 0.2884 | No |
| 48 | USP3 | USP3 Entrez, Source | ubiquitin specific peptidase 3 | 3981 | 0.037 | 0.2766 | No |
| 49 | SEMA3A | SEMA3A Entrez, Source | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 3987 | 0.037 | 0.2803 | No |
| 50 | ISL1 | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 4469 | 0.030 | 0.2473 | No |
| 51 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 4563 | 0.029 | 0.2436 | No |
| 52 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 4645 | 0.028 | 0.2406 | No |
| 53 | AXIN2 | AXIN2 Entrez, Source | axin 2 (conductin, axil) | 4670 | 0.028 | 0.2418 | No |
| 54 | TBXAS1 | TBXAS1 Entrez, Source | thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) | 4744 | 0.027 | 0.2393 | No |
| 55 | NOG | NOG Entrez, Source | noggin | 4913 | 0.025 | 0.2294 | No |
| 56 | PPP2R2B | PPP2R2B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 4958 | 0.024 | 0.2288 | No |
| 57 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 5072 | 0.023 | 0.2228 | No |
| 58 | PPP1CB | PPP1CB Entrez, Source | protein phosphatase 1, catalytic subunit, beta isoform | 5113 | 0.022 | 0.2222 | No |
| 59 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 5318 | 0.020 | 0.2090 | No |
| 60 | RASGRF2 | RASGRF2 Entrez, Source | Ras protein-specific guanine nucleotide-releasing factor 2 | 5342 | 0.020 | 0.2095 | No |
| 61 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 5474 | 0.019 | 0.2017 | No |
| 62 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 5645 | 0.017 | 0.1907 | No |
| 63 | PLAG1 | PLAG1 Entrez, Source | pleiomorphic adenoma gene 1 | 5765 | 0.015 | 0.1834 | No |
| 64 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | 0.1847 | No |
| 65 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 5821 | 0.015 | 0.1826 | No |
| 66 | SLC13A2 | SLC13A2 Entrez, Source | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 | 5825 | 0.015 | 0.1840 | No |
| 67 | SLC7A13 | SLC7A13 Entrez, Source | solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 | 5935 | 0.013 | 0.1773 | No |
| 68 | TMEM27 | TMEM27 Entrez, Source | transmembrane protein 27 | 6081 | 0.012 | 0.1676 | No |
| 69 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6202 | 0.011 | 0.1598 | No |
| 70 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 6549 | 0.007 | 0.1344 | No |
| 71 | RAB3IP | RAB3IP Entrez, Source | RAB3A interacting protein (rabin3) | 6732 | 0.005 | 0.1212 | No |
| 72 | HGFAC | HGFAC Entrez, Source | HGF activator | 6825 | 0.004 | 0.1147 | No |
| 73 | ALB | ALB Entrez, Source | albumin | 6888 | 0.003 | 0.1104 | No |
| 74 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6899 | 0.003 | 0.1099 | No |
| 75 | SFRP4 | SFRP4 Entrez, Source | secreted frizzled-related protein 4 | 6996 | 0.002 | 0.1029 | No |
| 76 | SERPINA10 | SERPINA10 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 7408 | -0.003 | 0.0721 | No |
| 77 | CS | CS Entrez, Source | citrate synthase | 7918 | -0.009 | 0.0346 | No |
| 78 | TCF1 | TCF1 Entrez, Source | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor | 7936 | -0.009 | 0.0343 | No |
| 79 | LRRFIP2 | LRRFIP2 Entrez, Source | leucine rich repeat (in FLII) interacting protein 2 | 8184 | -0.012 | 0.0169 | No |
| 80 | TFEC | TFEC Entrez, Source | transcription factor EC | 8378 | -0.014 | 0.0038 | No |
| 81 | NFIX | NFIX Entrez, Source | nuclear factor I/X (CCAAT-binding transcription factor) | 8634 | -0.017 | -0.0135 | No |
| 82 | SLC5A1 | SLC5A1 Entrez, Source | solute carrier family 5 (sodium/glucose cotransporter), member 1 | 8762 | -0.019 | -0.0210 | No |
| 83 | PDE4D | PDE4D Entrez, Source | phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) | 8922 | -0.021 | -0.0307 | No |
| 84 | SULF2 | SULF2 Entrez, Source | sulfatase 2 | 9050 | -0.023 | -0.0378 | No |
| 85 | POU2F1 | POU2F1 Entrez, Source | POU domain, class 2, transcription factor 1 | 9137 | -0.024 | -0.0417 | No |
| 86 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 9147 | -0.024 | -0.0398 | No |
| 87 | TRDN | TRDN Entrez, Source | triadin | 9180 | -0.024 | -0.0395 | No |
| 88 | BPHL | BPHL Entrez, Source | biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen) | 9370 | -0.027 | -0.0508 | No |
| 89 | SLC7A9 | SLC7A9 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 9724 | -0.032 | -0.0739 | No |
| 90 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 10268 | -0.041 | -0.1104 | No |
| 91 | TCF2 | TCF2 Entrez, Source | transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor | 10435 | -0.044 | -0.1180 | No |
| 92 | TINAG | TINAG Entrez, Source | tubulointerstitial nephritis antigen | 10796 | -0.051 | -0.1395 | No |
| 93 | NCOR1 | NCOR1 Entrez, Source | nuclear receptor co-repressor 1 | 10797 | -0.052 | -0.1338 | No |
| 94 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10913 | -0.054 | -0.1365 | No |
| 95 | CRB3 | CRB3 Entrez, Source | crumbs homolog 3 (Drosophila) | 11057 | -0.057 | -0.1410 | No |
| 96 | MAP2K5 | MAP2K5 Entrez, Source | mitogen-activated protein kinase kinase 5 | 11129 | -0.059 | -0.1398 | No |
| 97 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 11148 | -0.059 | -0.1346 | No |
| 98 | SLC4A4 | SLC4A4 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | 11283 | -0.062 | -0.1379 | No |
| 99 | PHLDB1 | PHLDB1 Entrez, Source | pleckstrin homology-like domain, family B, member 1 | 11311 | -0.063 | -0.1330 | No |
| 100 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 11604 | -0.072 | -0.1471 | No |
| 101 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 11851 | -0.081 | -0.1567 | No |
| 102 | PRICKLE1 | PRICKLE1 Entrez, Source | prickle homolog 1 (Drosophila) | 12357 | -0.107 | -0.1829 | No |
| 103 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 12424 | -0.112 | -0.1754 | No |
| 104 | F2RL1 | F2RL1 Entrez, Source | coagulation factor II (thrombin) receptor-like 1 | 12440 | -0.114 | -0.1640 | No |
| 105 | PBX2 | PBX2 Entrez, Source | pre-B-cell leukemia transcription factor 2 | 12471 | -0.116 | -0.1534 | No |
| 106 | TM4SF4 | TM4SF4 Entrez, Source | transmembrane 4 L six family member 4 | 12767 | -0.144 | -0.1598 | No |
| 107 | PDLIM1 | PDLIM1 Entrez, Source | PDZ and LIM domain 1 (elfin) | 12939 | -0.173 | -0.1534 | No |
| 108 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 12965 | -0.179 | -0.1354 | No |
| 109 | CDH17 | CDH17 Entrez, Source | cadherin 17, LI cadherin (liver-intestine) | 13046 | -0.205 | -0.1187 | No |
| 110 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13180 | -0.281 | -0.0976 | No |
| 111 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13211 | -0.304 | -0.0662 | No |
| 112 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.0315 | No |
| 113 | ARHGAP24 | ARHGAP24 Entrez, Source | Rho GTPase activating protein 24 | 13255 | -0.362 | 0.0066 | No |
