Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classdouble_gel_48h
GeneSetV$NMYC_01
Enrichment Score (ES)0.40328562
Normalized Enrichment Score (NES)1.6817528
Nominal p-value0.0031948881
FDR q-value0.061929967
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$NMYC_01   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ELOVL6ELOVL6
Entrez,  Source
ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)290.3130.0397Yes
2USP2USP2
Entrez,  Source
ubiquitin specific peptidase 2420.2930.0781Yes
3ABCA1ABCA1
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 1710.2510.1096Yes
4GADD45GGADD45G
Entrez,  Source
growth arrest and DNA-damage-inducible, gamma1600.1890.1283Yes
5CHRM1CHRM1
Entrez,  Source
cholinergic receptor, muscarinic 11690.1840.1524Yes
6SC5DLSC5DL
Entrez,  Source
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like1870.1760.1746Yes
7FKBP5FKBP5
Entrez,  Source
FK506 binding protein 52190.1690.1948Yes
8GPC3GPC3
Entrez,  Source
glypican 32210.1670.2171Yes
9POU3F1POU3F1
Entrez,  Source
POU domain, class 3, transcription factor 12910.1500.2320Yes
10RCL1RCL1
Entrez,  Source
RNA terminal phosphate cyclase-like 14320.1320.2391Yes
11GPD1GPD1
Entrez,  Source
glycerol-3-phosphate dehydrogenase 1 (soluble)5550.1210.2461Yes
12AP1GBP1AP1GBP1
Entrez,  Source
AP1 gamma subunit binding protein 15600.1210.2619Yes
13VGFVGF
Entrez,  Source
VGF nerve growth factor inducible5870.1190.2759Yes
14PPATPPAT
Entrez,  Source
phosphoribosyl pyrophosphate amidotransferase7090.1110.2816Yes
15ATAD3AATAD3A
Entrez,  Source
ATPase family, AAA domain containing 3A7210.1110.2956Yes
16CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta7320.1100.3095Yes
17DLC1DLC1
Entrez,  Source
deleted in liver cancer 19600.0990.3056Yes
18FGF11FGF11
Entrez,  Source
fibroblast growth factor 1110290.0960.3134Yes
19TESK2TESK2
Entrez,  Source
testis-specific kinase 211370.0920.3175Yes
20PPARGC1BPPARGC1B
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, beta11660.0910.3275Yes
21TIMM10TIMM10
Entrez,  Source
translocase of inner mitochondrial membrane 10 homolog (yeast)11980.0900.3372Yes
22DUSP4DUSP4
Entrez,  Source
dual specificity phosphatase 412250.0890.3471Yes
23HRSP12HRSP12
Entrez,  Source
heat-responsive protein 1212670.0870.3557Yes
24SLC20A1SLC20A1
Entrez,  Source
solute carrier family 20 (phosphate transporter), member 113080.0860.3641Yes
25MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase13920.0830.3690Yes
26SEPT3SEPT3
Entrez,  Source
septin 314290.0820.3772Yes
27ADCY3ADCY3
Entrez,  Source
adenylate cyclase 316110.0770.3738Yes
28WBP2WBP2
Entrez,  Source
WW domain binding protein 217250.0740.3751Yes
29DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 917490.0730.3831Yes
30ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)18220.0720.3873Yes
31PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa19580.0690.3863Yes
32LIG3LIG3
Entrez,  Source
ligase III, DNA, ATP-dependent20020.0680.3922Yes
33PRKCEPRKCE
Entrez,  Source
protein kinase C, epsilon20080.0680.4009Yes
34TIMM9TIMM9
Entrez,  Source
translocase of inner mitochondrial membrane 9 homolog (yeast)21180.0650.4014Yes
35BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase22070.0640.4033Yes
36NEF3NEF3
Entrez,  Source
neurofilament 3 (150kDa medium)25640.0570.3840No
37HMOX1HMOX1
Entrez,  Source
heme oxygenase (decycling) 127300.0550.3789No
38HMGN2HMGN2
Entrez,  Source
high-mobility group nucleosomal binding domain 230170.0500.3639No
39GCSHGCSH
Entrez,  Source
glycine cleavage system protein H (aminomethyl carrier)31260.0480.3622No
40DLX1DLX1
Entrez,  Source
distal-less homeobox 131500.0480.3669No
41NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)33460.0450.3582No
42IPO13IPO13
Entrez,  Source
importin 1335000.0430.3523No
43LAP3LAP3
Entrez,  Source
leucine aminopeptidase 336030.0420.3502No
44RXRBRXRB
Entrez,  Source
retinoid X receptor, beta36690.0410.3507No
45MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 337480.0400.3502No
46GRIN2AGRIN2A
Entrez,  Source
glutamate receptor, ionotropic, N-methyl D-aspartate 2A39050.0380.3434No
47TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I39190.0380.3475No
48FBLFBL
Entrez,  Source
fibrillarin40040.0360.3460No
49SLC12A5SLC12A5
Entrez,  Source
solute carrier family 12, (potassium-chloride transporter) member 541120.0350.3426No
50CACNA1DCACNA1D
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1D subunit43010.0330.3327No
51PLA2G4APLA2G4A
Entrez,  Source
phospholipase A2, group IVA (cytosolic, calcium-dependent)43070.0330.3367No
52BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 243280.0320.3395No
53PFKFB3PFKFB3
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 343970.0310.3385No
54TEFTEF
Entrez,  Source
thyrotrophic embryonic factor46230.0280.3253No
55RUNX2RUNX2
Entrez,  Source
runt-related transcription factor 247040.0270.3230No
56GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)47830.0270.3206No
57SGTBSGTB
Entrez,  Source
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta48190.0260.3214No
58MAPKAPK3MAPKAPK3
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 349260.0250.3167No
59NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)49790.0240.3160No
60NUP153NUP153
Entrez,  Source
nucleoporin 153kDa50470.0230.3141No
61HYAL2HYAL2
Entrez,  Source
hyaluronoglucosaminidase 252150.0210.3043No
62HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)52180.0210.3070No
63NRXN1NRXN1
Entrez,  Source
neurexin 152900.0200.3043No
64NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)54210.0190.2971No
65ADPRHL1ADPRHL1
Entrez,  Source
ADP-ribosylhydrolase like 154770.0190.2954No
66ANGPT2ANGPT2
Entrez,  Source
angiopoietin 255120.0180.2952No
67HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)56620.0160.2862No
68EIF4G1EIF4G1
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 157630.0150.2807No
69PLAG1PLAG1
Entrez,  Source
pleiomorphic adenoma gene 157650.0150.2826No
70HTF9CHTF9C
Entrez,  Source
-60470.0120.2630No
71NR1D1NR1D1
Entrez,  Source
nuclear receptor subfamily 1, group D, member 160580.0120.2639No
72COL2A1COL2A1
Entrez,  Source
collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)60630.0120.2652No
73FGF6FGF6
Entrez,  Source
fibroblast growth factor 661990.0110.2565No
74RAMP2RAMP2
Entrez,  Source
receptor (calcitonin) activity modifying protein 263980.0090.2427No
75PABPC1PABPC1
Entrez,  Source
poly(A) binding protein, cytoplasmic 164650.0080.2387No
76HPCAHPCA
Entrez,  Source
hippocalcin64740.0080.2392No
77ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 668990.0030.2075No
78PDK2PDK2
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 27313-0.0020.1765No
79CLCN2CLCN2
Entrez,  Source
chloride channel 27332-0.0020.1753No
80NEUROD2NEUROD2
Entrez,  Source
neurogenic differentiation 27475-0.0030.1651No
81SLC38A5SLC38A5
Entrez,  Source
solute carrier family 38, member 57548-0.0040.1602No
82HRH3HRH3
Entrez,  Source
histamine receptor H37593-0.0050.1575No
83RPL13ARPL13A
Entrez,  Source
ribosomal protein L13a7679-0.0060.1518No
84NXPH1NXPH1
Entrez,  Source
neurexophilin 17716-0.0060.1499No
85TLE3TLE3
Entrez,  Source
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)7718-0.0060.1506No
86APOA5APOA5
Entrez,  Source
apolipoprotein A-V7763-0.0070.1482No
87RBBP6RBBP6
Entrez,  Source
retinoblastoma binding protein 67799-0.0070.1465No
88PABPC4PABPC4
Entrez,  Source
poly(A) binding protein, cytoplasmic 4 (inducible form)8106-0.0110.1248No
89BARHL1BARHL1
Entrez,  Source
BarH-like 1 (Drosophila)8283-0.0130.1132No
90XTP3TPAXTP3TPA
Entrez,  Source
-8400-0.0140.1063No
91RPL22RPL22
Entrez,  Source
ribosomal protein L228557-0.0160.0967No
92DNMT3ADNMT3A
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 3 alpha8594-0.0170.0962No
93RAB2RAB2
Entrez,  Source
RAB2, member RAS oncogene family8693-0.0180.0912No
94ARHGAP20ARHGAP20
Entrez,  Source
Rho GTPase activating protein 208786-0.0190.0868No
95VPS16VPS16
Entrez,  Source
vacuolar protein sorting 16 (yeast)8885-0.0200.0821No
96HBP1HBP1
Entrez,  Source
HMG-box transcription factor 18915-0.0210.0826No
97STMN4STMN4
Entrez,  Source
stathmin-like 48943-0.0210.0834No
98RBM3RBM3
Entrez,  Source
RNA binding motif (RNP1, RRM) protein 39354-0.0270.0560No
99U2AF2U2AF2
Entrez,  Source
U2 small nuclear RNA auxiliary factor 29410-0.0280.0555No
100STAT3STAT3
Entrez,  Source
signal transducer and activator of transcription 3 (acute-phase response factor)9416-0.0280.0589No
101ZFP91ZFP91
Entrez,  Source
zinc finger protein 91 homolog (mouse)9444-0.0280.0606No
102SH3KBP1SH3KBP1
Entrez,  Source
SH3-domain kinase binding protein 19559-0.0300.0560No
103GPS1GPS1
Entrez,  Source
G protein pathway suppressor 19588-0.0300.0579No
104SLC9A5SLC9A5
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 59614-0.0310.0601No
105ANXA6ANXA6
Entrez,  Source
annexin A69885-0.0350.0443No
106PFN1PFN1
Entrez,  Source
profilin 110319-0.0420.0172No
107SCYL1SCYL1
Entrez,  Source
SCY1-like 1 (S. cerevisiae)10331-0.0420.0220No
108MAXMAX
Entrez,  Source
MYC associated factor X10590-0.0470.0087No
109GADD45BGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta10614-0.0470.0133No
110GIT1GIT1
Entrez,  Source
G protein-coupled receptor kinase interactor 110969-0.055-0.0061No
111CUGBP1CUGBP1
Entrez,  Source
CUG triplet repeat, RNA binding protein 111120-0.058-0.0096No
112ADAM10ADAM10
Entrez,  Source
ADAM metallopeptidase domain 1011154-0.059-0.0042No
113PRDX4PRDX4
Entrez,  Source
peroxiredoxin 411241-0.061-0.0025No
114PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 111247-0.0610.0053No
115EIF4BEIF4B
Entrez,  Source
eukaryotic translation initiation factor 4B11325-0.0630.0079No
116presenilin 2 (Alzheimer disease 4)PSEN2
Entrez,  Source
11726-0.076-0.0122No
117CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 211872-0.082-0.0122No
118GRK6GRK6
Entrez,  Source
G protein-coupled receptor kinase 611990-0.086-0.0095No
119G6PC3G6PC3
Entrez,  Source
glucose 6 phosphatase, catalytic, 312117-0.092-0.0067No
120NRASNRAS
Entrez,  Source
neuroblastoma RAS viral (v-ras) oncogene homolog12153-0.0940.0033No
121RAB30RAB30
Entrez,  Source
RAB30, member RAS oncogene family12489-0.117-0.0064No
122WEE1WEE1
Entrez,  Source
WEE1 homolog (S. pombe)12774-0.145-0.0085No
123CTSFCTSF
Entrez,  Source
cathepsin F12816-0.1500.0084No
124LMNB1LMNB1
Entrez,  Source
lamin B113104-0.2340.0180No
Table: GSEA details [plain text format]



Fig 2: V$NMYC_01   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$NMYC_01: Random ES distribution   
Gene set null distribution of ES for V$NMYC_01