Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$RORA2_01 |
| Enrichment Score (ES) | 0.379514 |
| Normalized Enrichment Score (NES) | 1.4599024 |
| Nominal p-value | 0.018817205 |
| FDR q-value | 0.17005281 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 71 | 0.251 | 0.0527 | Yes |
| 2 | CNTN6 | CNTN6 Entrez, Source | contactin 6 | 177 | 0.181 | 0.0867 | Yes |
| 3 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 265 | 0.156 | 0.1162 | Yes |
| 4 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 271 | 0.155 | 0.1516 | Yes |
| 5 | SLC18A2 | SLC18A2 Entrez, Source | solute carrier family 18 (vesicular monoamine), member 2 | 411 | 0.134 | 0.1721 | Yes |
| 6 | EPHA7 | EPHA7 Entrez, Source | EPH receptor A7 | 833 | 0.105 | 0.1648 | Yes |
| 7 | ADCYAP1 | ADCYAP1 Entrez, Source | adenylate cyclase activating polypeptide 1 (pituitary) | 918 | 0.101 | 0.1820 | Yes |
| 8 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 939 | 0.100 | 0.2036 | Yes |
| 9 | ACF | ACF Entrez, Source | - | 955 | 0.099 | 0.2254 | Yes |
| 10 | KIAA1443 | KIAA1443 Entrez, Source | KIAA1443 | 1169 | 0.091 | 0.2303 | Yes |
| 11 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 1240 | 0.088 | 0.2455 | Yes |
| 12 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 1264 | 0.087 | 0.2639 | Yes |
| 13 | CTH | CTH Entrez, Source | cystathionase (cystathionine gamma-lyase) | 1284 | 0.086 | 0.2825 | Yes |
| 14 | ATP1B2 | ATP1B2 Entrez, Source | ATPase, Na+/K+ transporting, beta 2 polypeptide | 1322 | 0.085 | 0.2994 | Yes |
| 15 | GABRB2 | GABRB2 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 2 | 1339 | 0.085 | 0.3178 | Yes |
| 16 | CAMKK2 | CAMKK2 Entrez, Source | calcium/calmodulin-dependent protein kinase kinase 2, beta | 1389 | 0.083 | 0.3333 | Yes |
| 17 | COX4I2 | COX4I2 Entrez, Source | cytochrome c oxidase subunit IV isoform 2 (lung) | 1405 | 0.082 | 0.3513 | Yes |
| 18 | OPN1SW | OPN1SW Entrez, Source | opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) | 1576 | 0.078 | 0.3565 | Yes |
| 19 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 1730 | 0.074 | 0.3620 | Yes |
| 20 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 1799 | 0.072 | 0.3735 | Yes |
| 21 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | 0.3795 | Yes |
| 22 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 2675 | 0.056 | 0.3367 | No |
| 23 | GUCY2F | GUCY2F Entrez, Source | guanylate cyclase 2F, retinal | 2753 | 0.054 | 0.3434 | No |
| 24 | CACNA1A | CACNA1A Entrez, Source | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 3318 | 0.046 | 0.3115 | No |
| 25 | PYGM | PYGM Entrez, Source | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | 3629 | 0.041 | 0.2977 | No |
| 26 | CLOCK | CLOCK Entrez, Source | clock homolog (mouse) | 3722 | 0.040 | 0.3001 | No |
| 27 | SEMA3A | SEMA3A Entrez, Source | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 3987 | 0.037 | 0.2886 | No |
| 28 | CITED1 | CITED1 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 5242 | 0.021 | 0.1990 | No |
| 29 | MPP2 | MPP2 Entrez, Source | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 5374 | 0.020 | 0.1937 | No |
| 30 | GRIA1 | GRIA1 Entrez, Source | glutamate receptor, ionotropic, AMPA 1 | 5442 | 0.019 | 0.1930 | No |
| 31 | SHH | SHH Entrez, Source | sonic hedgehog homolog (Drosophila) | 5547 | 0.018 | 0.1893 | No |
| 32 | REST | REST Entrez, Source | RE1-silencing transcription factor | 5566 | 0.018 | 0.1920 | No |
| 33 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 5996 | 0.013 | 0.1626 | No |
| 34 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 6400 | 0.009 | 0.1342 | No |
| 35 | HPCA | HPCA Entrez, Source | hippocalcin | 6474 | 0.008 | 0.1305 | No |
| 36 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 6539 | 0.007 | 0.1274 | No |
| 37 | ATP5H | ATP5H Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 6547 | 0.007 | 0.1285 | No |
| 38 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 6781 | 0.004 | 0.1119 | No |
| 39 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 6954 | 0.002 | 0.0995 | No |
| 40 | HNT | HNT Entrez, Source | - | 7016 | 0.002 | 0.0953 | No |
| 41 | RYR1 | RYR1 Entrez, Source | ryanodine receptor 1 (skeletal) | 7158 | 0.000 | 0.0848 | No |
| 42 | KHDRBS2 | KHDRBS2 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 2 | 7251 | -0.001 | 0.0780 | No |
| 43 | CHRDL1 | CHRDL1 Entrez, Source | chordin-like 1 | 7370 | -0.002 | 0.0697 | No |
| 44 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 7638 | -0.005 | 0.0507 | No |
| 45 | SLC4A7 | SLC4A7 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 7866 | -0.008 | 0.0355 | No |
| 46 | SLA | SLA Entrez, Source | Src-like-adaptor | 8073 | -0.010 | 0.0223 | No |
| 47 | SH3GL2 | SH3GL2 Entrez, Source | SH3-domain GRB2-like 2 | 8297 | -0.013 | 0.0085 | No |
| 48 | IL17F | IL17F Entrez, Source | interleukin 17F | 8354 | -0.014 | 0.0075 | No |
| 49 | KCNAB3 | KCNAB3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 3 | 9424 | -0.028 | -0.0666 | No |
| 50 | NUBP2 | NUBP2 Entrez, Source | nucleotide binding protein 2 (MinD homolog, E. coli) | 9489 | -0.029 | -0.0648 | No |
| 51 | MGEA5 | MGEA5 Entrez, Source | meningioma expressed antigen 5 (hyaluronidase) | 10016 | -0.037 | -0.0959 | No |
| 52 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 10023 | -0.037 | -0.0877 | No |
| 53 | ARF5 | ARF5 Entrez, Source | ADP-ribosylation factor 5 | 10443 | -0.044 | -0.1091 | No |
| 54 | AP3D1 | AP3D1 Entrez, Source | adaptor-related protein complex 3, delta 1 subunit | 10488 | -0.045 | -0.1020 | No |
| 55 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 10491 | -0.045 | -0.0917 | No |
| 56 | EPHA3 | EPHA3 Entrez, Source | EPH receptor A3 | 10877 | -0.053 | -0.1084 | No |
| 57 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 11148 | -0.059 | -0.1151 | No |
| 58 | DBP | DBP Entrez, Source | D site of albumin promoter (albumin D-box) binding protein | 11417 | -0.066 | -0.1201 | No |
| 59 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 11554 | -0.070 | -0.1141 | No |
| 60 | CIRBP | CIRBP Entrez, Source | cold inducible RNA binding protein | 11768 | -0.078 | -0.1121 | No |
| 61 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 11798 | -0.079 | -0.0961 | No |
| 62 | RALGPS2 | RALGPS2 Entrez, Source | Ral GEF with PH domain and SH3 binding motif 2 | 11810 | -0.080 | -0.0784 | No |
| 63 | TAF5L | TAF5L Entrez, Source | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 11820 | -0.080 | -0.0605 | No |
| 64 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 11939 | -0.085 | -0.0498 | No |
| 65 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 12465 | -0.115 | -0.0627 | No |
| 66 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12745 | -0.140 | -0.0513 | No |
| 67 | NMT2 | NMT2 Entrez, Source | N-myristoyltransferase 2 | 12913 | -0.168 | -0.0250 | No |
| 68 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 13130 | -0.247 | 0.0160 | No |
