Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$SREBP1_01 |
| Enrichment Score (ES) | -0.5047474 |
| Normalized Enrichment Score (NES) | -1.7749717 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.046589404 |
| FWER p-Value | 0.991 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 314 | 0.148 | 0.0035 | No |
| 2 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 404 | 0.135 | 0.0215 | No |
| 3 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 1257 | 0.088 | -0.0266 | No |
| 4 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 1429 | 0.082 | -0.0245 | No |
| 5 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 1586 | 0.077 | -0.0220 | No |
| 6 | GGN | GGN Entrez, Source | gametogenetin | 1651 | 0.076 | -0.0130 | No |
| 7 | HOXA2 | HOXA2 Entrez, Source | homeobox A2 | 1685 | 0.075 | -0.0018 | No |
| 8 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 2008 | 0.068 | -0.0136 | No |
| 9 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 2309 | 0.062 | -0.0249 | No |
| 10 | PIP5K1A | PIP5K1A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 2656 | 0.056 | -0.0406 | No |
| 11 | RAB3A | RAB3A Entrez, Source | RAB3A, member RAS oncogene family | 3041 | 0.049 | -0.0605 | No |
| 12 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 3123 | 0.048 | -0.0578 | No |
| 13 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 3516 | 0.043 | -0.0795 | No |
| 14 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3579 | 0.042 | -0.0764 | No |
| 15 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 3596 | 0.042 | -0.0700 | No |
| 16 | CANX | CANX Entrez, Source | calnexin | 3753 | 0.040 | -0.0744 | No |
| 17 | CUL5 | CUL5 Entrez, Source | cullin 5 | 3868 | 0.038 | -0.0760 | No |
| 18 | BLNK | BLNK Entrez, Source | B-cell linker | 3887 | 0.038 | -0.0703 | No |
| 19 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 4028 | 0.036 | -0.0743 | No |
| 20 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 4065 | 0.035 | -0.0705 | No |
| 21 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 4436 | 0.031 | -0.0927 | No |
| 22 | ACCN1 | ACCN1 Entrez, Source | amiloride-sensitive cation channel 1, neuronal (degenerin) | 4520 | 0.030 | -0.0935 | No |
| 23 | ADCY2 | ADCY2 Entrez, Source | adenylate cyclase 2 (brain) | 4953 | 0.024 | -0.1216 | No |
| 24 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 5406 | 0.019 | -0.1521 | No |
| 25 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 5560 | 0.018 | -0.1604 | No |
| 26 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 5577 | 0.017 | -0.1584 | No |
| 27 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 5763 | 0.015 | -0.1695 | No |
| 28 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6058 | 0.012 | -0.1894 | No |
| 29 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 6139 | 0.012 | -0.1933 | No |
| 30 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 6400 | 0.009 | -0.2114 | No |
| 31 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 6511 | 0.007 | -0.2183 | No |
| 32 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 6539 | 0.007 | -0.2190 | No |
| 33 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 6980 | 0.002 | -0.2518 | No |
| 34 | ATP6V0D1 | ATP6V0D1 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 7193 | -0.000 | -0.2678 | No |
| 35 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 7333 | -0.002 | -0.2779 | No |
| 36 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 7653 | -0.005 | -0.3010 | No |
| 37 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 7796 | -0.007 | -0.3104 | No |
| 38 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 8326 | -0.013 | -0.3478 | No |
| 39 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 8375 | -0.014 | -0.3489 | No |
| 40 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 8513 | -0.016 | -0.3563 | No |
| 41 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8593 | -0.017 | -0.3592 | No |
| 42 | ZDHHC13 | ZDHHC13 Entrez, Source | zinc finger, DHHC-type containing 13 | 9342 | -0.027 | -0.4107 | No |
| 43 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 9410 | -0.028 | -0.4107 | No |
| 44 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 9415 | -0.028 | -0.4059 | No |
| 45 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 9639 | -0.031 | -0.4170 | No |
| 46 | SUPT6H | SUPT6H Entrez, Source | suppressor of Ty 6 homolog (S. cerevisiae) | 9916 | -0.035 | -0.4314 | No |
| 47 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 10213 | -0.040 | -0.4463 | No |
| 48 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 10231 | -0.040 | -0.4402 | No |
| 49 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10281 | -0.041 | -0.4364 | No |
| 50 | PDCD6IP | PDCD6IP Entrez, Source | programmed cell death 6 interacting protein | 10580 | -0.047 | -0.4503 | No |
| 51 | HK2 | HK2 Entrez, Source | hexokinase 2 | 10644 | -0.048 | -0.4462 | No |
| 52 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 11325 | -0.063 | -0.4859 | No |
| 53 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 11576 | -0.071 | -0.4917 | Yes |
| 54 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11670 | -0.074 | -0.4850 | Yes |
| 55 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 11769 | -0.078 | -0.4782 | Yes |
| 56 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 12040 | -0.089 | -0.4822 | Yes |
| 57 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12047 | -0.089 | -0.4662 | Yes |
| 58 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12093 | -0.091 | -0.4529 | Yes |
| 59 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 12113 | -0.092 | -0.4375 | Yes |
| 60 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 12285 | -0.102 | -0.4316 | Yes |
| 61 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 12385 | -0.110 | -0.4189 | Yes |
| 62 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 12404 | -0.111 | -0.3998 | Yes |
| 63 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 12564 | -0.122 | -0.3893 | Yes |
| 64 | STX6 | STX6 Entrez, Source | syntaxin 6 | 12778 | -0.145 | -0.3788 | Yes |
| 65 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 12967 | -0.180 | -0.3600 | Yes |
| 66 | GRN | GRN Entrez, Source | granulin | 12971 | -0.181 | -0.3271 | Yes |
| 67 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13078 | -0.223 | -0.2942 | Yes |
| 68 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 13168 | -0.269 | -0.2516 | Yes |
| 69 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13184 | -0.284 | -0.2005 | Yes |
| 70 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13212 | -0.305 | -0.1466 | Yes |
| 71 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13280 | -0.405 | -0.0774 | Yes |
| 72 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | 0.0036 | Yes |
