Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$SRF_C |
| Enrichment Score (ES) | -0.5515234 |
| Normalized Enrichment Score (NES) | -2.0158825 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0066624074 |
| FWER p-Value | 0.173 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.0754 | No |
| 2 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.0896 | No |
| 3 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 160 | 0.189 | 0.0967 | No |
| 4 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 342 | 0.143 | 0.0936 | No |
| 5 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 546 | 0.122 | 0.0874 | No |
| 6 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 562 | 0.121 | 0.0952 | No |
| 7 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 752 | 0.109 | 0.0891 | No |
| 8 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 900 | 0.102 | 0.0856 | No |
| 9 | JPH2 | JPH2 Entrez, Source | junctophilin 2 | 1242 | 0.088 | 0.0664 | No |
| 10 | IER2 | IER2 Entrez, Source | immediate early response 2 | 1296 | 0.086 | 0.0688 | No |
| 11 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 1342 | 0.085 | 0.0717 | No |
| 12 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1428 | 0.082 | 0.0714 | No |
| 13 | TITF1 | TITF1 Entrez, Source | thyroid transcription factor 1 | 1498 | 0.079 | 0.0721 | No |
| 14 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 1556 | 0.078 | 0.0736 | No |
| 15 | GGN | GGN Entrez, Source | gametogenetin | 1651 | 0.076 | 0.0722 | No |
| 16 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | 0.0560 | No |
| 17 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 1957 | 0.069 | 0.0595 | No |
| 18 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 2001 | 0.068 | 0.0614 | No |
| 19 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2033 | 0.067 | 0.0640 | No |
| 20 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 2177 | 0.064 | 0.0580 | No |
| 21 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 2696 | 0.055 | 0.0230 | No |
| 22 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 2720 | 0.055 | 0.0254 | No |
| 23 | IL17B | IL17B Entrez, Source | interleukin 17B | 2802 | 0.053 | 0.0232 | No |
| 24 | RASD2 | RASD2 Entrez, Source | RASD family, member 2 | 2943 | 0.051 | 0.0164 | No |
| 25 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 3328 | 0.045 | -0.0092 | No |
| 26 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 3375 | 0.045 | -0.0093 | No |
| 27 | MCAM | MCAM Entrez, Source | melanoma cell adhesion molecule | 3499 | 0.043 | -0.0154 | No |
| 28 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 3543 | 0.042 | -0.0155 | No |
| 29 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 3598 | 0.042 | -0.0165 | No |
| 30 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 3919 | 0.038 | -0.0379 | No |
| 31 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 4117 | 0.035 | -0.0502 | No |
| 32 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 4121 | 0.035 | -0.0478 | No |
| 33 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 4322 | 0.032 | -0.0605 | No |
| 34 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 4456 | 0.031 | -0.0683 | No |
| 35 | GFPT2 | GFPT2 Entrez, Source | glutamine-fructose-6-phosphate transaminase 2 | 4497 | 0.030 | -0.0690 | No |
| 36 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 4499 | 0.030 | -0.0669 | No |
| 37 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 4645 | 0.028 | -0.0757 | No |
| 38 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 5318 | 0.020 | -0.1250 | No |
| 39 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 5319 | 0.020 | -0.1235 | No |
| 40 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 5408 | 0.019 | -0.1287 | No |
| 41 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 5463 | 0.019 | -0.1314 | No |
| 42 | CKM | CKM Entrez, Source | creatine kinase, muscle | 5748 | 0.015 | -0.1517 | No |
| 43 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 5777 | 0.015 | -0.1527 | No |
| 44 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 5875 | 0.014 | -0.1590 | No |
| 45 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 5955 | 0.013 | -0.1639 | No |
| 46 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 6113 | 0.012 | -0.1749 | No |
| 47 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 6511 | 0.007 | -0.2044 | No |
| 48 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 6719 | 0.005 | -0.2196 | No |
| 49 | MATR3 | MATR3 Entrez, Source | matrin 3 | 6931 | 0.003 | -0.2354 | No |
| 50 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 6992 | 0.002 | -0.2398 | No |
| 51 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 7024 | 0.002 | -0.2420 | No |
| 52 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 7116 | 0.001 | -0.2488 | No |
| 53 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 7121 | 0.001 | -0.2490 | No |
| 54 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 7547 | -0.004 | -0.2808 | No |
| 55 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 7690 | -0.006 | -0.2911 | No |
| 56 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 7718 | -0.006 | -0.2927 | No |
| 57 | PRKAB2 | PRKAB2 Entrez, Source | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 7852 | -0.008 | -0.3022 | No |
| 58 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 8419 | -0.014 | -0.3439 | No |
| 59 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 8801 | -0.019 | -0.3712 | No |
| 60 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 9039 | -0.022 | -0.3875 | No |
| 61 | EGR4 | EGR4 Entrez, Source | early growth response 4 | 9181 | -0.024 | -0.3963 | No |
| 62 | MYO1B | MYO1B Entrez, Source | myosin IB | 9460 | -0.028 | -0.4152 | No |
| 63 | POU3F4 | POU3F4 Entrez, Source | POU domain, class 3, transcription factor 4 | 9521 | -0.029 | -0.4176 | No |
| 64 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 9599 | -0.030 | -0.4211 | No |
| 65 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9885 | -0.035 | -0.4401 | No |
| 66 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 9887 | -0.035 | -0.4376 | No |
| 67 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 10313 | -0.042 | -0.4666 | No |
| 68 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10319 | -0.042 | -0.4638 | No |
| 69 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 10430 | -0.044 | -0.4689 | No |
| 70 | TCF2 | TCF2 Entrez, Source | transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor | 10435 | -0.044 | -0.4659 | No |
| 71 | PNKP | PNKP Entrez, Source | polynucleotide kinase 3'-phosphatase | 10534 | -0.046 | -0.4699 | No |
| 72 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 10537 | -0.046 | -0.4666 | No |
| 73 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 10736 | -0.050 | -0.4778 | No |
| 74 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 10820 | -0.052 | -0.4802 | No |
| 75 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11062 | -0.057 | -0.4942 | No |
| 76 | ACTB | ACTB Entrez, Source | actin, beta | 11264 | -0.061 | -0.5048 | No |
| 77 | DAPK3 | DAPK3 Entrez, Source | death-associated protein kinase 3 | 11659 | -0.074 | -0.5290 | No |
| 78 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 11757 | -0.077 | -0.5306 | No |
| 79 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11921 | -0.084 | -0.5367 | No |
| 80 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 11990 | -0.086 | -0.5354 | No |
| 81 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12205 | -0.097 | -0.5443 | Yes |
| 82 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12207 | -0.097 | -0.5371 | Yes |
| 83 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 12239 | -0.099 | -0.5321 | Yes |
| 84 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12330 | -0.106 | -0.5310 | Yes |
| 85 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12489 | -0.117 | -0.5343 | Yes |
| 86 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 12545 | -0.121 | -0.5294 | Yes |
| 87 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12557 | -0.122 | -0.5211 | Yes |
| 88 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12599 | -0.125 | -0.5149 | Yes |
| 89 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12710 | -0.136 | -0.5131 | Yes |
| 90 | MYO1E | MYO1E Entrez, Source | myosin IE | 12727 | -0.138 | -0.5040 | Yes |
| 91 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12735 | -0.139 | -0.4941 | Yes |
| 92 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12748 | -0.141 | -0.4846 | Yes |
| 93 | PLN | PLN Entrez, Source | phospholamban | 12849 | -0.156 | -0.4805 | Yes |
| 94 | SSH3 | SSH3 Entrez, Source | slingshot homolog 3 (Drosophila) | 12854 | -0.157 | -0.4691 | Yes |
| 95 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 12919 | -0.170 | -0.4613 | Yes |
| 96 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12996 | -0.187 | -0.4531 | Yes |
| 97 | RNF39 | RNF39 Entrez, Source | ring finger protein 39 | 13089 | -0.226 | -0.4431 | Yes |
| 98 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 13193 | -0.289 | -0.4293 | Yes |
| 99 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 13231 | -0.327 | -0.4078 | Yes |
| 100 | POPDC2 | POPDC2 Entrez, Source | popeye domain containing 2 | 13266 | -0.379 | -0.3821 | Yes |
| 101 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13280 | -0.405 | -0.3529 | Yes |
| 102 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13281 | -0.405 | -0.3227 | Yes |
| 103 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13298 | -0.461 | -0.2895 | Yes |
| 104 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.2545 | Yes |
| 105 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13307 | -0.479 | -0.2190 | Yes |
| 106 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13332 | -0.725 | -0.1668 | Yes |
| 107 | TAGLN | TAGLN Entrez, Source | transgelin | 13341 | -1.059 | -0.0885 | Yes |
| 108 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | 0.0000 | Yes |
