Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$SRF_Q4 |
| Enrichment Score (ES) | -0.47348872 |
| Normalized Enrichment Score (NES) | -1.7652436 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.048237827 |
| FWER p-Value | 0.995 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.0779 | No |
| 2 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.0926 | No |
| 3 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 160 | 0.189 | 0.1002 | No |
| 4 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 292 | 0.150 | 0.1018 | No |
| 5 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 342 | 0.143 | 0.1091 | No |
| 6 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 394 | 0.136 | 0.1158 | No |
| 7 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 546 | 0.122 | 0.1137 | No |
| 8 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 562 | 0.121 | 0.1219 | No |
| 9 | SORT1 | SORT1 Entrez, Source | sortilin 1 | 578 | 0.119 | 0.1299 | No |
| 10 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 587 | 0.119 | 0.1385 | No |
| 11 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 801 | 0.107 | 0.1306 | No |
| 12 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 1024 | 0.096 | 0.1213 | No |
| 13 | JPH2 | JPH2 Entrez, Source | junctophilin 2 | 1242 | 0.088 | 0.1116 | No |
| 14 | IER2 | IER2 Entrez, Source | immediate early response 2 | 1296 | 0.086 | 0.1142 | No |
| 15 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 1342 | 0.085 | 0.1173 | No |
| 16 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1428 | 0.082 | 0.1172 | No |
| 17 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 1623 | 0.077 | 0.1085 | No |
| 18 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 1645 | 0.076 | 0.1127 | No |
| 19 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 1884 | 0.070 | 0.1001 | No |
| 20 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | 0.1018 | No |
| 21 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 1957 | 0.069 | 0.1054 | No |
| 22 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2033 | 0.067 | 0.1049 | No |
| 23 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 2046 | 0.067 | 0.1092 | No |
| 24 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 2177 | 0.064 | 0.1043 | No |
| 25 | COL23A1 | COL23A1 Entrez, Source | collagen, type XXIII, alpha 1 | 2290 | 0.062 | 0.1006 | No |
| 26 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 2398 | 0.060 | 0.0972 | No |
| 27 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 2696 | 0.055 | 0.0790 | No |
| 28 | IL17B | IL17B Entrez, Source | interleukin 17B | 2802 | 0.053 | 0.0751 | No |
| 29 | RASD2 | RASD2 Entrez, Source | RASD family, member 2 | 2943 | 0.051 | 0.0685 | No |
| 30 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 3080 | 0.049 | 0.0620 | No |
| 31 | FGF17 | FGF17 Entrez, Source | fibroblast growth factor 17 | 3105 | 0.049 | 0.0639 | No |
| 32 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 3328 | 0.045 | 0.0506 | No |
| 33 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 3375 | 0.045 | 0.0506 | No |
| 34 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 3492 | 0.043 | 0.0451 | No |
| 35 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 3543 | 0.042 | 0.0446 | No |
| 36 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 3545 | 0.042 | 0.0478 | No |
| 37 | SND1 | SND1 Entrez, Source | - | 3595 | 0.042 | 0.0473 | No |
| 38 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 3598 | 0.042 | 0.0503 | No |
| 39 | KCNJ13 | KCNJ13 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 13 | 3761 | 0.040 | 0.0412 | No |
| 40 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 3880 | 0.038 | 0.0352 | No |
| 41 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 4117 | 0.035 | 0.0200 | No |
| 42 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 4322 | 0.032 | 0.0071 | No |
| 43 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 4456 | 0.031 | -0.0006 | No |
| 44 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 4499 | 0.030 | -0.0015 | No |
| 45 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 4645 | 0.028 | -0.0103 | No |
| 46 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 5463 | 0.019 | -0.0706 | No |
| 47 | GAB2 | GAB2 Entrez, Source | GRB2-associated binding protein 2 | 5597 | 0.017 | -0.0794 | No |
| 48 | CKM | CKM Entrez, Source | creatine kinase, muscle | 5748 | 0.015 | -0.0895 | No |
| 49 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 5777 | 0.015 | -0.0905 | No |
| 50 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 5875 | 0.014 | -0.0967 | No |
| 51 | NLGN3 | NLGN3 Entrez, Source | neuroligin 3 | 6029 | 0.013 | -0.1073 | No |
| 52 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 6113 | 0.012 | -0.1127 | No |
| 53 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 6481 | 0.008 | -0.1398 | No |
| 54 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 6511 | 0.007 | -0.1415 | No |
| 55 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 6834 | 0.004 | -0.1655 | No |
| 56 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 6992 | 0.002 | -0.1772 | No |
| 57 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 7024 | 0.002 | -0.1794 | No |
| 58 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 7116 | 0.001 | -0.1863 | No |
| 59 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 7121 | 0.001 | -0.1865 | No |
| 60 | SRP54 | SRP54 Entrez, Source | signal recognition particle 54kDa | 7534 | -0.004 | -0.2173 | No |
| 61 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 7547 | -0.004 | -0.2179 | No |
| 62 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 7690 | -0.006 | -0.2282 | No |
| 63 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 7718 | -0.006 | -0.2298 | No |
| 64 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 8145 | -0.011 | -0.2612 | No |
| 65 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 8419 | -0.014 | -0.2807 | No |
| 66 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 8473 | -0.015 | -0.2835 | No |
| 67 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 9039 | -0.022 | -0.3245 | No |
| 68 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 9085 | -0.023 | -0.3261 | No |
| 69 | EGR4 | EGR4 Entrez, Source | early growth response 4 | 9181 | -0.024 | -0.3315 | No |
| 70 | IHPK1 | IHPK1 Entrez, Source | inositol hexaphosphate kinase 1 | 9248 | -0.025 | -0.3345 | No |
| 71 | TNMD | TNMD Entrez, Source | tenomodulin | 9425 | -0.028 | -0.3457 | No |
| 72 | MYO1B | MYO1B Entrez, Source | myosin IB | 9460 | -0.028 | -0.3461 | No |
| 73 | POU3F4 | POU3F4 Entrez, Source | POU domain, class 3, transcription factor 4 | 9521 | -0.029 | -0.3484 | No |
| 74 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 9599 | -0.030 | -0.3518 | No |
| 75 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9885 | -0.035 | -0.3707 | No |
| 76 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 10103 | -0.038 | -0.3842 | No |
| 77 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10319 | -0.042 | -0.3972 | No |
| 78 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 10430 | -0.044 | -0.4021 | No |
| 79 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 10736 | -0.050 | -0.4213 | No |
| 80 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 10820 | -0.052 | -0.4236 | No |
| 81 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10913 | -0.054 | -0.4264 | No |
| 82 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11062 | -0.057 | -0.4332 | No |
| 83 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 11190 | -0.060 | -0.4382 | No |
| 84 | ACTB | ACTB Entrez, Source | actin, beta | 11264 | -0.061 | -0.4390 | No |
| 85 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.4624 | No |
| 86 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 11798 | -0.079 | -0.4674 | Yes |
| 87 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 11799 | -0.079 | -0.4614 | Yes |
| 88 | TAF5L | TAF5L Entrez, Source | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 11820 | -0.080 | -0.4567 | Yes |
| 89 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11841 | -0.081 | -0.4520 | Yes |
| 90 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 11975 | -0.086 | -0.4554 | Yes |
| 91 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 11990 | -0.086 | -0.4498 | Yes |
| 92 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12205 | -0.097 | -0.4585 | Yes |
| 93 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12207 | -0.097 | -0.4511 | Yes |
| 94 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 12239 | -0.099 | -0.4459 | Yes |
| 95 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 12240 | -0.099 | -0.4383 | Yes |
| 96 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12330 | -0.106 | -0.4368 | Yes |
| 97 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 12388 | -0.110 | -0.4327 | Yes |
| 98 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12473 | -0.116 | -0.4301 | Yes |
| 99 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12489 | -0.117 | -0.4223 | Yes |
| 100 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 12545 | -0.121 | -0.4171 | Yes |
| 101 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12599 | -0.125 | -0.4115 | Yes |
| 102 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12710 | -0.136 | -0.4093 | Yes |
| 103 | MYO1E | MYO1E Entrez, Source | myosin IE | 12727 | -0.138 | -0.3999 | Yes |
| 104 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12735 | -0.139 | -0.3897 | Yes |
| 105 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12832 | -0.153 | -0.3852 | Yes |
| 106 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.3821 | Yes |
| 107 | TMOD1 | TMOD1 Entrez, Source | tropomodulin 1 | 12990 | -0.186 | -0.3685 | Yes |
| 108 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12996 | -0.187 | -0.3544 | Yes |
| 109 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 13031 | -0.199 | -0.3417 | Yes |
| 110 | FST | FST Entrez, Source | follistatin | 13176 | -0.277 | -0.3312 | Yes |
| 111 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.3101 | Yes |
| 112 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 13296 | -0.454 | -0.2804 | Yes |
| 113 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13298 | -0.461 | -0.2449 | Yes |
| 114 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.2089 | Yes |
| 115 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13313 | -0.503 | -0.1708 | Yes |
| 116 | TAGLN | TAGLN Entrez, Source | transgelin | 13341 | -1.059 | -0.0914 | Yes |
| 117 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | 0.0000 | Yes |
