Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$SRF_Q5_01 |
| Enrichment Score (ES) | -0.47900164 |
| Normalized Enrichment Score (NES) | -1.7650332 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.047918707 |
| FWER p-Value | 0.995 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.0775 | No |
| 2 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.0922 | No |
| 3 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 71 | 0.251 | 0.1111 | No |
| 4 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 160 | 0.189 | 0.1190 | No |
| 5 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 292 | 0.150 | 0.1206 | No |
| 6 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 329 | 0.145 | 0.1290 | No |
| 7 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 342 | 0.143 | 0.1390 | No |
| 8 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 394 | 0.136 | 0.1456 | No |
| 9 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 546 | 0.122 | 0.1436 | No |
| 10 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 801 | 0.107 | 0.1326 | No |
| 11 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 900 | 0.102 | 0.1330 | No |
| 12 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 1152 | 0.091 | 0.1210 | No |
| 13 | IER2 | IER2 Entrez, Source | immediate early response 2 | 1296 | 0.086 | 0.1168 | No |
| 14 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 1342 | 0.085 | 0.1199 | No |
| 15 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 1623 | 0.077 | 0.1046 | No |
| 16 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 1645 | 0.076 | 0.1088 | No |
| 17 | GGN | GGN Entrez, Source | gametogenetin | 1651 | 0.076 | 0.1143 | No |
| 18 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 1884 | 0.070 | 0.1021 | No |
| 19 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 1957 | 0.069 | 0.1020 | No |
| 20 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 1971 | 0.069 | 0.1063 | No |
| 21 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 1996 | 0.068 | 0.1097 | No |
| 22 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2033 | 0.067 | 0.1121 | No |
| 23 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 2046 | 0.067 | 0.1163 | No |
| 24 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 2177 | 0.064 | 0.1115 | No |
| 25 | COL23A1 | COL23A1 Entrez, Source | collagen, type XXIII, alpha 1 | 2290 | 0.062 | 0.1078 | No |
| 26 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 2361 | 0.061 | 0.1071 | No |
| 27 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 2696 | 0.055 | 0.0861 | No |
| 28 | IL17B | IL17B Entrez, Source | interleukin 17B | 2802 | 0.053 | 0.0823 | No |
| 29 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 2925 | 0.051 | 0.0770 | No |
| 30 | FGF17 | FGF17 Entrez, Source | fibroblast growth factor 17 | 3105 | 0.049 | 0.0672 | No |
| 31 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 3328 | 0.045 | 0.0539 | No |
| 32 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 3332 | 0.045 | 0.0572 | No |
| 33 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 3375 | 0.045 | 0.0574 | No |
| 34 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 3492 | 0.043 | 0.0520 | No |
| 35 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 3543 | 0.042 | 0.0514 | No |
| 36 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 3545 | 0.042 | 0.0546 | No |
| 37 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3579 | 0.042 | 0.0553 | No |
| 38 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 3880 | 0.038 | 0.0356 | No |
| 39 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 4117 | 0.035 | 0.0204 | No |
| 40 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 4322 | 0.032 | 0.0075 | No |
| 41 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 4456 | 0.031 | -0.0002 | No |
| 42 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 4462 | 0.030 | 0.0017 | No |
| 43 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 4499 | 0.030 | 0.0013 | No |
| 44 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 4645 | 0.028 | -0.0075 | No |
| 45 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 5408 | 0.019 | -0.0636 | No |
| 46 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 5463 | 0.019 | -0.0663 | No |
| 47 | CKM | CKM Entrez, Source | creatine kinase, muscle | 5748 | 0.015 | -0.0865 | No |
| 48 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 5777 | 0.015 | -0.0875 | No |
| 49 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 5875 | 0.014 | -0.0937 | No |
| 50 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 6113 | 0.012 | -0.1107 | No |
| 51 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 6481 | 0.008 | -0.1379 | No |
| 52 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 6834 | 0.004 | -0.1642 | No |
| 53 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6899 | 0.003 | -0.1688 | No |
| 54 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 7024 | 0.002 | -0.1780 | No |
| 55 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 7116 | 0.001 | -0.1848 | No |
| 56 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 7121 | 0.001 | -0.1851 | No |
| 57 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 7547 | -0.004 | -0.2169 | No |
| 58 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 7718 | -0.006 | -0.2292 | No |
| 59 | PRKAB2 | PRKAB2 Entrez, Source | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 7852 | -0.008 | -0.2387 | No |
| 60 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 8145 | -0.011 | -0.2599 | No |
| 61 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 8419 | -0.014 | -0.2794 | No |
| 62 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 8473 | -0.015 | -0.2823 | No |
| 63 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 8843 | -0.020 | -0.3086 | No |
| 64 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 9039 | -0.022 | -0.3217 | No |
| 65 | TRDN | TRDN Entrez, Source | triadin | 9180 | -0.024 | -0.3304 | No |
| 66 | TNMD | TNMD Entrez, Source | tenomodulin | 9425 | -0.028 | -0.3467 | No |
| 67 | OTX1 | OTX1 Entrez, Source | orthodenticle homolog 1 (Drosophila) | 9487 | -0.029 | -0.3491 | No |
| 68 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 9599 | -0.030 | -0.3551 | No |
| 69 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9885 | -0.035 | -0.3740 | No |
| 70 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 10103 | -0.038 | -0.3875 | No |
| 71 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10319 | -0.042 | -0.4005 | No |
| 72 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 10430 | -0.044 | -0.4055 | No |
| 73 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 10619 | -0.047 | -0.4160 | No |
| 74 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 10736 | -0.050 | -0.4210 | No |
| 75 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 10820 | -0.052 | -0.4233 | No |
| 76 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11062 | -0.057 | -0.4371 | No |
| 77 | ACTB | ACTB Entrez, Source | actin, beta | 11264 | -0.061 | -0.4476 | No |
| 78 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.4711 | No |
| 79 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 11757 | -0.077 | -0.4731 | Yes |
| 80 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 11799 | -0.079 | -0.4701 | Yes |
| 81 | TAF5L | TAF5L Entrez, Source | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 11820 | -0.080 | -0.4655 | Yes |
| 82 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11841 | -0.081 | -0.4608 | Yes |
| 83 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11921 | -0.084 | -0.4603 | Yes |
| 84 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 11990 | -0.086 | -0.4589 | Yes |
| 85 | TRIM3 | TRIM3 Entrez, Source | tripartite motif-containing 3 | 12028 | -0.088 | -0.4549 | Yes |
| 86 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 12153 | -0.094 | -0.4570 | Yes |
| 87 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12205 | -0.097 | -0.4534 | Yes |
| 88 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12207 | -0.097 | -0.4461 | Yes |
| 89 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 12239 | -0.099 | -0.4409 | Yes |
| 90 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 12240 | -0.099 | -0.4333 | Yes |
| 91 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 12285 | -0.102 | -0.4288 | Yes |
| 92 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12473 | -0.116 | -0.4340 | Yes |
| 93 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 12545 | -0.121 | -0.4301 | Yes |
| 94 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12710 | -0.136 | -0.4321 | Yes |
| 95 | MYO1E | MYO1E Entrez, Source | myosin IE | 12727 | -0.138 | -0.4227 | Yes |
| 96 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12735 | -0.139 | -0.4126 | Yes |
| 97 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12832 | -0.153 | -0.4081 | Yes |
| 98 | PLN | PLN Entrez, Source | phospholamban | 12849 | -0.156 | -0.3973 | Yes |
| 99 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12996 | -0.187 | -0.3940 | Yes |
| 100 | MYADM | MYADM Entrez, Source | myeloid-associated differentiation marker | 13119 | -0.239 | -0.3849 | Yes |
| 101 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 13175 | -0.275 | -0.3680 | Yes |
| 102 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.3471 | Yes |
| 103 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 13231 | -0.327 | -0.3223 | Yes |
| 104 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13280 | -0.405 | -0.2949 | Yes |
| 105 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13298 | -0.461 | -0.2609 | Yes |
| 106 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.2249 | Yes |
| 107 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13332 | -0.725 | -0.1715 | Yes |
| 108 | TAGLN | TAGLN Entrez, Source | transgelin | 13341 | -1.059 | -0.0910 | Yes |
| 109 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | 0.0000 | Yes |
