Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | V$TEF1_Q6 |
| Enrichment Score (ES) | -0.46507815 |
| Normalized Enrichment Score (NES) | -1.7036687 |
| Nominal p-value | 0.001472754 |
| FDR q-value | 0.06602035 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BBOX1 | BBOX1 Entrez, Source | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 37 | 0.303 | 0.0290 | No |
| 2 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 42 | 0.293 | 0.0595 | No |
| 3 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.0847 | No |
| 4 | SLK | SLK Entrez, Source | STE20-like kinase (yeast) | 361 | 0.141 | 0.0772 | No |
| 5 | FGFR2 | FGFR2 Entrez, Source | ffer syndrome, Jackson-Weiss syndrome) | 419 | 0.133 | 0.0869 | No |
| 6 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 469 | 0.128 | 0.0966 | No |
| 7 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 616 | 0.117 | 0.0979 | No |
| 8 | SLC6A13 | SLC6A13 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 797 | 0.107 | 0.0956 | No |
| 9 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 869 | 0.104 | 0.1011 | No |
| 10 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 1028 | 0.096 | 0.0993 | No |
| 11 | SYT2 | SYT2 Entrez, Source | synaptotagmin II | 1220 | 0.089 | 0.0942 | No |
| 12 | CD2 | CD2 Entrez, Source | CD2 molecule | 1336 | 0.085 | 0.0944 | No |
| 13 | PRRX1 | PRRX1 Entrez, Source | paired related homeobox 1 | 1739 | 0.073 | 0.0718 | No |
| 14 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 1799 | 0.072 | 0.0749 | No |
| 15 | SLC17A6 | SLC17A6 Entrez, Source | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 | 1935 | 0.069 | 0.0720 | No |
| 16 | TNNI3K | TNNI3K Entrez, Source | TNNI3 interacting kinase | 2155 | 0.065 | 0.0623 | No |
| 17 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 2177 | 0.064 | 0.0675 | No |
| 18 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 2194 | 0.064 | 0.0730 | No |
| 19 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 2417 | 0.060 | 0.0625 | No |
| 20 | PRKAA2 | PRKAA2 Entrez, Source | protein kinase, AMP-activated, alpha 2 catalytic subunit | 2659 | 0.056 | 0.0502 | No |
| 21 | FOLR1 | FOLR1 Entrez, Source | folate receptor 1 (adult) | 2708 | 0.055 | 0.0524 | No |
| 22 | DNM3 | DNM3 Entrez, Source | dynamin 3 | 2812 | 0.053 | 0.0502 | No |
| 23 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 3017 | 0.050 | 0.0400 | No |
| 24 | CACNA1S | CACNA1S Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1S subunit | 3213 | 0.047 | 0.0302 | No |
| 25 | ABCG4 | ABCG4 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 4 | 3363 | 0.045 | 0.0237 | No |
| 26 | MCAM | MCAM Entrez, Source | melanoma cell adhesion molecule | 3499 | 0.043 | 0.0180 | No |
| 27 | IPO13 | IPO13 Entrez, Source | importin 13 | 3500 | 0.043 | 0.0225 | No |
| 28 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 3652 | 0.041 | 0.0154 | No |
| 29 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 3666 | 0.041 | 0.0187 | No |
| 30 | SLC6A9 | SLC6A9 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 3930 | 0.037 | 0.0028 | No |
| 31 | MPZ | MPZ Entrez, Source | myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) | 3998 | 0.036 | 0.0016 | No |
| 32 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 4121 | 0.035 | -0.0040 | No |
| 33 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 4456 | 0.031 | -0.0260 | No |
| 34 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 4640 | 0.028 | -0.0368 | No |
| 35 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 4758 | 0.027 | -0.0429 | No |
| 36 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 5334 | 0.020 | -0.0842 | No |
| 37 | SYT8 | SYT8 Entrez, Source | synaptotagmin VIII | 5405 | 0.019 | -0.0874 | No |
| 38 | CHKA | CHKA Entrez, Source | choline kinase alpha | 5540 | 0.018 | -0.0957 | No |
| 39 | EHD1 | EHD1 Entrez, Source | EH-domain containing 1 | 5679 | 0.016 | -0.1044 | No |
| 40 | ELF3 | ELF3 Entrez, Source | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 5740 | 0.016 | -0.1073 | No |
| 41 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.1079 | No |
| 42 | VAX1 | VAX1 Entrez, Source | ventral anterior homeobox 1 | 5863 | 0.014 | -0.1133 | No |
| 43 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 6130 | 0.012 | -0.1322 | No |
| 44 | CACNA1E | CACNA1E Entrez, Source | calcium channel, voltage-dependent, alpha 1E subunit | 6182 | 0.011 | -0.1349 | No |
| 45 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 6199 | 0.011 | -0.1349 | No |
| 46 | MUC1 | MUC1 Entrez, Source | mucin 1, cell surface associated | 6417 | 0.008 | -0.1504 | No |
| 47 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 6472 | 0.008 | -0.1537 | No |
| 48 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 6529 | 0.007 | -0.1571 | No |
| 49 | PTPRJ | PTPRJ Entrez, Source | protein tyrosine phosphatase, receptor type, J | 6741 | 0.005 | -0.1725 | No |
| 50 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7160 | 0.000 | -0.2041 | No |
| 51 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 7644 | -0.005 | -0.2400 | No |
| 52 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 7708 | -0.006 | -0.2441 | No |
| 53 | SDCCAG8 | SDCCAG8 Entrez, Source | serologically defined colon cancer antigen 8 | 8414 | -0.014 | -0.2958 | No |
| 54 | FXYD6 | FXYD6 Entrez, Source | FXYD domain containing ion transport regulator 6 | 8670 | -0.018 | -0.3132 | No |
| 55 | DEDD | DEDD Entrez, Source | death effector domain containing | 9042 | -0.022 | -0.3389 | No |
| 56 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 9383 | -0.027 | -0.3617 | No |
| 57 | DAB1 | DAB1 Entrez, Source | disabled homolog 1 (Drosophila) | 9526 | -0.029 | -0.3693 | No |
| 58 | HDGF | HDGF Entrez, Source | hepatoma-derived growth factor (high-mobility group protein 1-like) | 9633 | -0.031 | -0.3741 | No |
| 59 | PPP2R1B | PPP2R1B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | 9775 | -0.033 | -0.3812 | No |
| 60 | SLC39A13 | SLC39A13 Entrez, Source | solute carrier family 39 (zinc transporter), member 13 | 9964 | -0.036 | -0.3917 | No |
| 61 | RNF2 | RNF2 Entrez, Source | ring finger protein 2 | 10149 | -0.039 | -0.4014 | No |
| 62 | CNNM2 | CNNM2 Entrez, Source | cyclin M2 | 10379 | -0.043 | -0.4142 | No |
| 63 | RTN3 | RTN3 Entrez, Source | reticulon 3 | 10382 | -0.043 | -0.4098 | No |
| 64 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10521 | -0.046 | -0.4155 | No |
| 65 | ANXA8 | ANXA8 Entrez, Source | annexin A8 | 10533 | -0.046 | -0.4115 | No |
| 66 | DR1 | DR1 Entrez, Source | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 10633 | -0.048 | -0.4139 | No |
| 67 | ADIPOR1 | ADIPOR1 Entrez, Source | adiponectin receptor 1 | 10701 | -0.049 | -0.4138 | No |
| 68 | SCN2B | SCN2B Entrez, Source | sodium channel, voltage-gated, type II, beta | 10782 | -0.051 | -0.4145 | No |
| 69 | PRKCDBP | PRKCDBP Entrez, Source | protein kinase C, delta binding protein | 10837 | -0.052 | -0.4131 | No |
| 70 | IL18BP | IL18BP Entrez, Source | interleukin 18 binding protein | 11209 | -0.060 | -0.4347 | No |
| 71 | PTMS | PTMS Entrez, Source | parathymosin | 11215 | -0.061 | -0.4287 | No |
| 72 | IER5 | IER5 Entrez, Source | immediate early response 5 | 11328 | -0.063 | -0.4306 | No |
| 73 | MADD | MADD Entrez, Source | MAP-kinase activating death domain | 11375 | -0.064 | -0.4273 | No |
| 74 | NPPB | NPPB Entrez, Source | natriuretic peptide precursor B | 11482 | -0.068 | -0.4282 | No |
| 75 | AVPI1 | AVPI1 Entrez, Source | arginine vasopressin-induced 1 | 11561 | -0.070 | -0.4267 | No |
| 76 | BRMS1 | BRMS1 Entrez, Source | breast cancer metastasis suppressor 1 | 11603 | -0.072 | -0.4222 | No |
| 77 | FRAG1 | FRAG1 Entrez, Source | - | 12172 | -0.095 | -0.4551 | Yes |
| 78 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12192 | -0.096 | -0.4464 | Yes |
| 79 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 12240 | -0.099 | -0.4396 | Yes |
| 80 | PIAS3 | PIAS3 Entrez, Source | protein inhibitor of activated STAT, 3 | 12301 | -0.103 | -0.4332 | Yes |
| 81 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 12465 | -0.115 | -0.4334 | Yes |
| 82 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 12489 | -0.117 | -0.4229 | Yes |
| 83 | LMNA | LMNA Entrez, Source | lamin A/C | 12554 | -0.122 | -0.4150 | Yes |
| 84 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12557 | -0.122 | -0.4023 | Yes |
| 85 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 12684 | -0.133 | -0.3978 | Yes |
| 86 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12745 | -0.140 | -0.3876 | Yes |
| 87 | JAM3 | JAM3 Entrez, Source | junctional adhesion molecule 3 | 12897 | -0.164 | -0.3818 | Yes |
| 88 | NES | NES Entrez, Source | nestin | 12908 | -0.167 | -0.3650 | Yes |
| 89 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 13024 | -0.196 | -0.3531 | Yes |
| 90 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 13206 | -0.298 | -0.3355 | Yes |
| 91 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13212 | -0.305 | -0.3039 | Yes |
| 92 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 13233 | -0.329 | -0.2709 | Yes |
| 93 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 13270 | -0.390 | -0.2327 | Yes |
| 94 | PEA15 | PEA15 Entrez, Source | phosphoprotein enriched in astrocytes 15 | 13282 | -0.412 | -0.1902 | Yes |
| 95 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 13330 | -0.666 | -0.1238 | Yes |
| 96 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | 0.0000 | Yes |
