Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | VANTVEER_BREAST_OUTCOME_GOOD_VS_POOR_DN |
| Enrichment Score (ES) | -0.59164375 |
| Normalized Enrichment Score (NES) | -1.799025 |
| Nominal p-value | 0.003407155 |
| FDR q-value | 0.043166097 |
| FWER p-Value | 0.977 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 439 | 0.131 | 0.0026 | No |
| 2 | NMU | NMU Entrez, Source | neuromedin U | 1515 | 0.079 | -0.0567 | No |
| 3 | TMEFF1 | TMEFF1 Entrez, Source | transmembrane protein with EGF-like and two follistatin-like domains 1 | 1642 | 0.076 | -0.0456 | No |
| 4 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 1769 | 0.073 | -0.0353 | No |
| 5 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 1883 | 0.070 | -0.0247 | No |
| 6 | STX1A | STX1A Entrez, Source | syntaxin 1A (brain) | 2346 | 0.061 | -0.0428 | No |
| 7 | CP | CP Entrez, Source | ceruloplasmin (ferroxidase) | 2438 | 0.060 | -0.0334 | No |
| 8 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2629 | 0.056 | -0.0324 | No |
| 9 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 2997 | 0.050 | -0.0464 | No |
| 10 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 3532 | 0.042 | -0.0750 | No |
| 11 | MGAT4A | MGAT4A Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 4171 | 0.034 | -0.1136 | No |
| 12 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 5075 | 0.023 | -0.1753 | No |
| 13 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 5123 | 0.022 | -0.1727 | No |
| 14 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 5619 | 0.017 | -0.2053 | No |
| 15 | PTDSS1 | PTDSS1 Entrez, Source | phosphatidylserine synthase 1 | 6320 | 0.009 | -0.2554 | No |
| 16 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 7248 | -0.001 | -0.3249 | No |
| 17 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 7426 | -0.003 | -0.3374 | No |
| 18 | ASNS | ASNS Entrez, Source | asparagine synthetase | 7614 | -0.005 | -0.3501 | No |
| 19 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8388 | -0.014 | -0.4043 | No |
| 20 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.4221 | No |
| 21 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9333 | -0.026 | -0.4632 | No |
| 22 | ST7 | ST7 Entrez, Source | suppression of tumorigenicity 7 | 9977 | -0.036 | -0.5017 | No |
| 23 | DCK | DCK Entrez, Source | deoxycytidine kinase | 10358 | -0.043 | -0.5187 | No |
| 24 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 10619 | -0.047 | -0.5254 | No |
| 25 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 10702 | -0.049 | -0.5181 | No |
| 26 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11253 | -0.061 | -0.5428 | No |
| 27 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 11904 | -0.084 | -0.5689 | Yes |
| 28 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 11999 | -0.087 | -0.5524 | Yes |
| 29 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 12105 | -0.092 | -0.5354 | Yes |
| 30 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12243 | -0.099 | -0.5188 | Yes |
| 31 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12396 | -0.111 | -0.5002 | Yes |
| 32 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12798 | -0.147 | -0.4903 | Yes |
| 33 | AKAP2 | AKAP2 Entrez, Source | A kinase (PRKA) anchor protein 2 | 13096 | -0.230 | -0.4500 | Yes |
| 34 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13242 | -0.345 | -0.3673 | Yes |
| 35 | ADM | ADM Entrez, Source | adrenomedullin | 13274 | -0.393 | -0.2627 | Yes |
| 36 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.1372 | Yes |
| 37 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | 0.0018 | Yes |
