Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | VESICULAR_FRACTION |
| Enrichment Score (ES) | 0.5951843 |
| Normalized Enrichment Score (NES) | 1.8093122 |
| Nominal p-value | 0.002202643 |
| FDR q-value | 0.028722264 |
| FWER p-Value | 0.883 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | AADAC | AADAC Entrez, Source | arylacetamide deacetylase (esterase) | 59 | 0.269 | 0.1894 | Yes |
| 2 | IRS1 | IRS1 Entrez, Source | insulin receptor substrate 1 | 233 | 0.163 | 0.2941 | Yes |
| 3 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 975 | 0.099 | 0.3095 | Yes |
| 4 | HSD17B3 | HSD17B3 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 3 | 1112 | 0.093 | 0.3663 | Yes |
| 5 | APOB | APOB Entrez, Source | apolipoprotein B (including Ag(x) antigen) | 1560 | 0.078 | 0.3891 | Yes |
| 6 | CYP2C9 | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 1777 | 0.073 | 0.4253 | Yes |
| 7 | SLC35B1 | SLC35B1 Entrez, Source | solute carrier family 35, member B1 | 2250 | 0.063 | 0.4354 | Yes |
| 8 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 2646 | 0.056 | 0.4463 | Yes |
| 9 | COMT | COMT Entrez, Source | catechol-O-methyltransferase | 2832 | 0.053 | 0.4704 | Yes |
| 10 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 3007 | 0.050 | 0.4933 | Yes |
| 11 | DHRS9 | DHRS9 Entrez, Source | dehydrogenase/reductase (SDR family) member 9 | 3288 | 0.046 | 0.5054 | Yes |
| 12 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 3400 | 0.044 | 0.5291 | Yes |
| 13 | SSR3 | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 3557 | 0.042 | 0.5478 | Yes |
| 14 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 3630 | 0.041 | 0.5722 | Yes |
| 15 | POMGNT1 | POMGNT1 Entrez, Source | protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase | 3720 | 0.040 | 0.5946 | Yes |
| 16 | TMED2 | TMED2 Entrez, Source | transmembrane emp24 domain trafficking protein 2 | 4183 | 0.034 | 0.5844 | Yes |
| 17 | FMO3 | FMO3 Entrez, Source | flavin containing monooxygenase 3 | 4348 | 0.032 | 0.5952 | Yes |
| 18 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 5536 | 0.018 | 0.5190 | No |
| 19 | COPA | COPA Entrez, Source | coatomer protein complex, subunit alpha | 6618 | 0.006 | 0.4424 | No |
| 20 | STX2 | STX2 Entrez, Source | syntaxin 2 | 7010 | 0.002 | 0.4143 | No |
| 21 | TMED10 | TMED10 Entrez, Source | transmembrane emp24-like trafficking protein 10 (yeast) | 7149 | 0.000 | 0.4042 | No |
| 22 | ERO1L | ERO1L Entrez, Source | ERO1-like (S. cerevisiae) | 7209 | -0.000 | 0.4001 | No |
| 23 | VCP | VCP Entrez, Source | valosin-containing protein | 7832 | -0.007 | 0.3587 | No |
| 24 | LTC4S | LTC4S Entrez, Source | leukotriene C4 synthase | 7935 | -0.009 | 0.3574 | No |
| 25 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 9652 | -0.031 | 0.2511 | No |
| 26 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 9956 | -0.036 | 0.2543 | No |
