Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ZUCCHI_EPITHELIAL_DN |
| Enrichment Score (ES) | -0.7019198 |
| Normalized Enrichment Score (NES) | -2.093015 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0037281536 |
| FWER p-Value | 0.048 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RASD1 | RASD1 Entrez, Source | RAS, dexamethasone-induced 1 | 200 | 0.173 | 0.0380 | No |
| 2 | AREG | AREG Entrez, Source | amphiregulin (schwannoma-derived growth factor) | 1977 | 0.069 | -0.0743 | No |
| 3 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2033 | 0.067 | -0.0578 | No |
| 4 | LIF | LIF Entrez, Source | leukemia inhibitory factor (cholinergic differentiation factor) | 2660 | 0.056 | -0.0877 | No |
| 5 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 3354 | 0.045 | -0.1259 | No |
| 6 | JUND | JUND Entrez, Source | jun D proto-oncogene | 4884 | 0.025 | -0.2329 | No |
| 7 | DDX5 | DDX5 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 5329 | 0.020 | -0.2601 | No |
| 8 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 5622 | 0.017 | -0.2769 | No |
| 9 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 5627 | 0.017 | -0.2721 | No |
| 10 | PPM1G | PPM1G Entrez, Source | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 5880 | 0.014 | -0.2867 | No |
| 11 | EIF3S4 | EIF3S4 Entrez, Source | eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa | 6121 | 0.012 | -0.3011 | No |
| 12 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.3557 | No |
| 13 | YWHAE | YWHAE Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 6904 | 0.003 | -0.3578 | No |
| 14 | DDB1 | DDB1 Entrez, Source | damage-specific DNA binding protein 1, 127kDa | 7576 | -0.005 | -0.4067 | No |
| 15 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 8149 | -0.011 | -0.4463 | No |
| 16 | ST13 | ST13 Entrez, Source | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 8448 | -0.015 | -0.4641 | No |
| 17 | HMGN1 | HMGN1 Entrez, Source | high-mobility group nucleosome binding domain 1 | 9508 | -0.029 | -0.5347 | No |
| 18 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10319 | -0.042 | -0.5828 | No |
| 19 | PNRC1 | PNRC1 Entrez, Source | proline-rich nuclear receptor coactivator 1 | 10332 | -0.042 | -0.5708 | No |
| 20 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 10614 | -0.047 | -0.5774 | No |
| 21 | CST3 | CST3 Entrez, Source | cystatin C (amyloid angiopathy and cerebral hemorrhage) | 12273 | -0.101 | -0.6708 | Yes |
| 22 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 12285 | -0.102 | -0.6402 | Yes |
| 23 | LMNA | LMNA Entrez, Source | lamin A/C | 12554 | -0.122 | -0.6229 | Yes |
| 24 | SCGB1D2 | SCGB1D2 Entrez, Source | secretoglobin, family 1D, member 2 | 12606 | -0.126 | -0.5882 | Yes |
| 25 | PDLIM1 | PDLIM1 Entrez, Source | PDZ and LIM domain 1 (elfin) | 12939 | -0.173 | -0.5599 | Yes |
| 26 | CLDN4 | CLDN4 Entrez, Source | claudin 4 | 12969 | -0.181 | -0.5066 | Yes |
| 27 | ZYX | ZYX Entrez, Source | zyxin | 13115 | -0.238 | -0.4443 | Yes |
| 28 | LGALS3 | LGALS3 Entrez, Source | lectin, galactoside-binding, soluble, 3 (galectin 3) | 13164 | -0.267 | -0.3658 | Yes |
| 29 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13254 | -0.355 | -0.2634 | Yes |
| 30 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 13267 | -0.380 | -0.1475 | Yes |
| 31 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13312 | -0.498 | 0.0023 | Yes |
