Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | AACTGAC,MIR-223 |
| Enrichment Score (ES) | -0.56285906 |
| Normalized Enrichment Score (NES) | -1.772892 |
| Nominal p-value | 0.0017421603 |
| FDR q-value | 0.042086024 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FBXO8 | FBXO8 Entrez, Source | F-box protein 8 | 604 | 0.186 | -0.0100 | No |
| 2 | VNN1 | VNN1 Entrez, Source | vanin 1 | 2659 | 0.075 | -0.1503 | No |
| 3 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 2800 | 0.071 | -0.1472 | No |
| 4 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 3139 | 0.064 | -0.1605 | No |
| 5 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3241 | 0.061 | -0.1564 | No |
| 6 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 3378 | 0.058 | -0.1555 | No |
| 7 | CSNK1G1 | CSNK1G1 Entrez, Source | casein kinase 1, gamma 1 | 3501 | 0.056 | -0.1540 | No |
| 8 | RPS6KB1 | RPS6KB1 Entrez, Source | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 3665 | 0.053 | -0.1563 | No |
| 9 | IL6ST | IL6ST Entrez, Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 3732 | 0.051 | -0.1514 | No |
| 10 | RBM16 | RBM16 Entrez, Source | RNA binding motif protein 16 | 3735 | 0.051 | -0.1418 | No |
| 11 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 4004 | 0.046 | -0.1532 | No |
| 12 | NFIA | NFIA Entrez, Source | nuclear factor I/A | 4861 | 0.032 | -0.2116 | No |
| 13 | PKNOX1 | PKNOX1 Entrez, Source | PBX/knotted 1 homeobox 1 | 5077 | 0.028 | -0.2224 | No |
| 14 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 5439 | 0.023 | -0.2453 | No |
| 15 | HERC4 | HERC4 Entrez, Source | hect domain and RLD 4 | 5658 | 0.019 | -0.2580 | No |
| 16 | SON | SON Entrez, Source | SON DNA binding protein | 5809 | 0.017 | -0.2660 | No |
| 17 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 5922 | 0.015 | -0.2715 | No |
| 18 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 6039 | 0.014 | -0.2776 | No |
| 19 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 6047 | 0.014 | -0.2755 | No |
| 20 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 6260 | 0.010 | -0.2895 | No |
| 21 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 6515 | 0.006 | -0.3075 | No |
| 22 | RASSF4 | RASSF4 Entrez, Source | Ras association (RalGDS/AF-6) domain family 4 | 6714 | 0.004 | -0.3217 | No |
| 23 | OLFM1 | OLFM1 Entrez, Source | olfactomedin 1 | 7102 | -0.002 | -0.3505 | No |
| 24 | PDPK1 | PDPK1 Entrez, Source | 3-phosphoinositide dependent protein kinase-1 | 7143 | -0.002 | -0.3530 | No |
| 25 | RAP2A | RAP2A Entrez, Source | RAP2A, member of RAS oncogene family | 7385 | -0.006 | -0.3701 | No |
| 26 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 7404 | -0.006 | -0.3703 | No |
| 27 | UBE2A | UBE2A Entrez, Source | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 7458 | -0.007 | -0.3730 | No |
| 28 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 7984 | -0.015 | -0.4097 | No |
| 29 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 8085 | -0.016 | -0.4141 | No |
| 30 | ANKRD16 | ANKRD16 Entrez, Source | ankyrin repeat domain 16 | 8322 | -0.020 | -0.4280 | No |
| 31 | INPP5B | INPP5B Entrez, Source | inositol polyphosphate-5-phosphatase, 75kDa | 8397 | -0.021 | -0.4295 | No |
| 32 | RNF4 | RNF4 Entrez, Source | ring finger protein 4 | 8531 | -0.024 | -0.4351 | No |
| 33 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 9748 | -0.047 | -0.5176 | No |
| 34 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 9765 | -0.047 | -0.5099 | No |
| 35 | PDE4D | PDE4D Entrez, Source | phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) | 10306 | -0.059 | -0.5392 | No |
| 36 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 10405 | -0.062 | -0.5348 | No |
| 37 | MTPN | MTPN Entrez, Source | myotrophin | 10651 | -0.068 | -0.5402 | No |
| 38 | SOX11 | SOX11 Entrez, Source | SRY (sex determining region Y)-box 11 | 10773 | -0.072 | -0.5356 | No |
| 39 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 11136 | -0.083 | -0.5470 | Yes |
| 40 | SPRED1 | SPRED1 Entrez, Source | sprouty-related, EVH1 domain containing 1 | 11241 | -0.088 | -0.5381 | Yes |
| 41 | SCN3A | SCN3A Entrez, Source | sodium channel, voltage-gated, type III, alpha | 11403 | -0.095 | -0.5321 | Yes |
| 42 | KPNA3 | KPNA3 Entrez, Source | karyopherin alpha 3 (importin alpha 4) | 11464 | -0.098 | -0.5179 | Yes |
| 43 | SLC23A2 | SLC23A2 Entrez, Source | solute carrier family 23 (nucleobase transporters), member 2 | 11687 | -0.108 | -0.5139 | Yes |
| 44 | RALGPS2 | RALGPS2 Entrez, Source | Ral GEF with PH domain and SH3 binding motif 2 | 11922 | -0.120 | -0.5086 | Yes |
| 45 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11988 | -0.124 | -0.4899 | Yes |
| 46 | RAB8B | RAB8B Entrez, Source | RAB8B, member RAS oncogene family | 12056 | -0.128 | -0.4704 | Yes |
| 47 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12184 | -0.138 | -0.4537 | Yes |
| 48 | RNF34 | RNF34 Entrez, Source | ring finger protein 34 | 12344 | -0.152 | -0.4366 | Yes |
| 49 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12381 | -0.156 | -0.4095 | Yes |
| 50 | CBFB | CBFB Entrez, Source | core-binding factor, beta subunit | 12396 | -0.157 | -0.3805 | Yes |
| 51 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12680 | -0.201 | -0.3635 | Yes |
| 52 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12813 | -0.228 | -0.3299 | Yes |
| 53 | RCN2 | RCN2 Entrez, Source | reticulocalbin 2, EF-hand calcium binding domain | 13128 | -0.381 | -0.2808 | Yes |
| 54 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | -0.1497 | Yes |
| 55 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13308 | -0.800 | 0.0026 | Yes |
