Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | ACTIN_BINDING |
| Enrichment Score (ES) | -0.6077631 |
| Normalized Enrichment Score (NES) | -1.7728578 |
| Nominal p-value | 0.0036630037 |
| FDR q-value | 0.04176959 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 635 | 0.182 | -0.0117 | No |
| 2 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 686 | 0.175 | 0.0191 | No |
| 3 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 804 | 0.162 | 0.0425 | No |
| 4 | LRPPRC | LRPPRC Entrez, Source | leucine-rich PPR-motif containing | 838 | 0.159 | 0.0714 | No |
| 5 | SCIN | SCIN Entrez, Source | scinderin | 1491 | 0.114 | 0.0450 | No |
| 6 | GC | GC Entrez, Source | group-specific component (vitamin D binding protein) | 2397 | 0.082 | -0.0067 | No |
| 7 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 2763 | 0.072 | -0.0199 | No |
| 8 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 3365 | 0.059 | -0.0534 | No |
| 9 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 3680 | 0.052 | -0.0666 | No |
| 10 | ABRA | ABRA Entrez, Source | actin-binding Rho activating protein | 4015 | 0.046 | -0.0826 | No |
| 11 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 4079 | 0.045 | -0.0785 | No |
| 12 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4891 | 0.031 | -0.1333 | No |
| 13 | ESPN | ESPN Entrez, Source | espin | 6685 | 0.004 | -0.2672 | No |
| 14 | NCALD | NCALD Entrez, Source | neurocalcin delta | 7040 | -0.001 | -0.2937 | No |
| 15 | MEFV | MEFV Entrez, Source | Mediterranean fever | 7182 | -0.003 | -0.3037 | No |
| 16 | ARPC1A | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 8191 | -0.018 | -0.3759 | No |
| 17 | GABARAPL2 | GABARAPL2 Entrez, Source | GABA(A) receptor-associated protein-like 2 | 8493 | -0.023 | -0.3940 | No |
| 18 | HPCA | HPCA Entrez, Source | hippocalcin | 9596 | -0.043 | -0.4682 | No |
| 19 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 9737 | -0.046 | -0.4696 | No |
| 20 | CCR5 | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 9822 | -0.048 | -0.4663 | No |
| 21 | SYNPO | SYNPO Entrez, Source | synaptopodin | 9931 | -0.051 | -0.4644 | No |
| 22 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 10092 | -0.054 | -0.4657 | No |
| 23 | DBNL | DBNL Entrez, Source | drebrin-like | 10207 | -0.057 | -0.4630 | No |
| 24 | MYO9B | MYO9B Entrez, Source | myosin IXB | 12134 | -0.133 | -0.5814 | Yes |
| 25 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12231 | -0.142 | -0.5604 | Yes |
| 26 | ADD1 | ADD1 Entrez, Source | adducin 1 (alpha) | 12334 | -0.152 | -0.5381 | Yes |
| 27 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 12383 | -0.156 | -0.5108 | Yes |
| 28 | SMTN | SMTN Entrez, Source | smoothelin | 12423 | -0.161 | -0.4818 | Yes |
| 29 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12456 | -0.165 | -0.4516 | Yes |
| 30 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12690 | -0.203 | -0.4290 | Yes |
| 31 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 12803 | -0.226 | -0.3927 | Yes |
| 32 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12871 | -0.243 | -0.3497 | Yes |
| 33 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12969 | -0.279 | -0.3018 | Yes |
| 34 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 13236 | -0.522 | -0.2185 | Yes |
| 35 | NEXN | NEXN Entrez, Source | nexilin (F actin binding protein) | 13256 | -0.568 | -0.1075 | Yes |
| 36 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 13261 | -0.575 | 0.0061 | Yes |
