Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | ACTIN_CYTOSKELETON |
| Enrichment Score (ES) | -0.69659346 |
| Normalized Enrichment Score (NES) | -2.2570834 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 314 | 0.263 | 0.0049 | No |
| 2 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 804 | 0.162 | -0.0142 | No |
| 3 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 1352 | 0.121 | -0.0422 | No |
| 4 | SNIP | SNIP Entrez, Source | - | 2122 | 0.090 | -0.0902 | No |
| 5 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 2130 | 0.090 | -0.0809 | No |
| 6 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 2763 | 0.072 | -0.1207 | No |
| 7 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 2930 | 0.068 | -0.1257 | No |
| 8 | ABRA | ABRA Entrez, Source | actin-binding Rho activating protein | 4015 | 0.046 | -0.2023 | No |
| 9 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 4128 | 0.044 | -0.2060 | No |
| 10 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4891 | 0.031 | -0.2600 | No |
| 11 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 4951 | 0.030 | -0.2612 | No |
| 12 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 4962 | 0.030 | -0.2587 | No |
| 13 | AVIL | AVIL Entrez, Source | advillin | 5268 | 0.025 | -0.2789 | No |
| 14 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5315 | 0.024 | -0.2797 | No |
| 15 | AMPH | AMPH Entrez, Source | amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) | 6291 | 0.010 | -0.3521 | No |
| 16 | DYNLL2 | DYNLL2 Entrez, Source | dynein, light chain, LC8-type 2 | 6549 | 0.006 | -0.3708 | No |
| 17 | ESPN | ESPN Entrez, Source | espin | 6685 | 0.004 | -0.3805 | No |
| 18 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 7348 | -0.005 | -0.4298 | No |
| 19 | HAP1 | HAP1 Entrez, Source | huntingtin-associated protein 1 (neuroan 1) | 7797 | -0.012 | -0.4622 | No |
| 20 | ACTR1B | ACTR1B Entrez, Source | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | 7815 | -0.012 | -0.4622 | No |
| 21 | ARPC1A | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 8191 | -0.018 | -0.4885 | No |
| 22 | CORO1A | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 8440 | -0.022 | -0.5047 | No |
| 23 | MYH7 | MYH7 Entrez, Source | myosin, heavy chain 7, cardiac muscle, beta | 8532 | -0.024 | -0.5090 | No |
| 24 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 9345 | -0.039 | -0.5660 | No |
| 25 | SYNPO | SYNPO Entrez, Source | synaptopodin | 9931 | -0.051 | -0.6045 | No |
| 26 | ABLIM2 | ABLIM2 Entrez, Source | actin binding LIM protein family, member 2 | 10013 | -0.052 | -0.6049 | No |
| 27 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 10092 | -0.054 | -0.6049 | No |
| 28 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 10153 | -0.056 | -0.6033 | No |
| 29 | SEPT9 | SEPT9 Entrez, Source | septin 9 | 10261 | -0.058 | -0.6051 | No |
| 30 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 10348 | -0.060 | -0.6050 | No |
| 31 | ACTL7B | ACTL7B Entrez, Source | actin-like 7B | 10635 | -0.068 | -0.6191 | No |
| 32 | SLC9A3R1 | SLC9A3R1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 11571 | -0.103 | -0.6784 | No |
| 33 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 11814 | -0.114 | -0.6841 | Yes |
| 34 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11968 | -0.123 | -0.6823 | Yes |
| 35 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11979 | -0.123 | -0.6696 | Yes |
| 36 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 12015 | -0.126 | -0.6585 | Yes |
| 37 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 12035 | -0.127 | -0.6461 | Yes |
| 38 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12086 | -0.130 | -0.6356 | Yes |
| 39 | MYO9B | MYO9B Entrez, Source | myosin IXB | 12134 | -0.133 | -0.6247 | Yes |
| 40 | SEPT7 | SEPT7 Entrez, Source | septin 7 | 12144 | -0.134 | -0.6108 | Yes |
| 41 | CASK | CASK Entrez, Source | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 12154 | -0.135 | -0.5968 | Yes |
| 42 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 12204 | -0.140 | -0.5853 | Yes |
| 43 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12231 | -0.142 | -0.5718 | Yes |
| 44 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 12383 | -0.156 | -0.5661 | Yes |
| 45 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12397 | -0.157 | -0.5500 | Yes |
| 46 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12398 | -0.157 | -0.5328 | Yes |
| 47 | SMTN | SMTN Entrez, Source | smoothelin | 12423 | -0.161 | -0.5171 | Yes |
| 48 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12456 | -0.165 | -0.5016 | Yes |
| 49 | KALRN | KALRN Entrez, Source | kalirin, RhoGEF kinase | 12509 | -0.172 | -0.4868 | Yes |
| 50 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 12548 | -0.178 | -0.4702 | Yes |
| 51 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12577 | -0.181 | -0.4527 | Yes |
| 52 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 12675 | -0.199 | -0.4383 | Yes |
| 53 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 12692 | -0.203 | -0.4174 | Yes |
| 54 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 12793 | -0.222 | -0.4007 | Yes |
| 55 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 12803 | -0.226 | -0.3768 | Yes |
| 56 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 12818 | -0.229 | -0.3530 | Yes |
| 57 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12846 | -0.236 | -0.3293 | Yes |
| 58 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12969 | -0.279 | -0.3081 | Yes |
| 59 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.2789 | Yes |
| 60 | MYO1C | MYO1C Entrez, Source | myosin IC | 13017 | -0.300 | -0.2467 | Yes |
| 61 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 13065 | -0.327 | -0.2146 | Yes |
| 62 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 13261 | -0.575 | -0.1666 | Yes |
| 63 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
