Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | ADIP_VS_FIBRO_UP |
| Enrichment Score (ES) | 0.5244502 |
| Normalized Enrichment Score (NES) | 1.5831184 |
| Nominal p-value | 0.020179372 |
| FDR q-value | 0.0747305 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FASN | FASN Entrez, Source | fatty acid synthase | 101 | 0.417 | 0.0957 | Yes |
| 2 | PC | PC Entrez, Source | pyruvate carboxylase | 155 | 0.347 | 0.1778 | Yes |
| 3 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 207 | 0.307 | 0.2500 | Yes |
| 4 | GHR | GHR Entrez, Source | growth hormone receptor | 250 | 0.287 | 0.3181 | Yes |
| 5 | ACADVL | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 482 | 0.207 | 0.3520 | Yes |
| 6 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 609 | 0.185 | 0.3884 | Yes |
| 7 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 662 | 0.178 | 0.4286 | Yes |
| 8 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 901 | 0.153 | 0.4486 | Yes |
| 9 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 1087 | 0.138 | 0.4688 | Yes |
| 10 | AGT | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 1201 | 0.130 | 0.4925 | Yes |
| 11 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 1471 | 0.115 | 0.5007 | Yes |
| 12 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 1632 | 0.107 | 0.5153 | Yes |
| 13 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 1840 | 0.100 | 0.5245 | Yes |
| 14 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 2929 | 0.068 | 0.4596 | No |
| 15 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 3416 | 0.058 | 0.4374 | No |
| 16 | COX8A | COX8A Entrez, Source | cytochrome c oxidase subunit 8A (ubiquitous) | 3448 | 0.057 | 0.4492 | No |
| 17 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 3592 | 0.054 | 0.4518 | No |
| 18 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 4794 | 0.033 | 0.3697 | No |
| 19 | GPX4 | GPX4 Entrez, Source | glutathione peroxidase 4 (phospholipid hydroperoxidase) | 5373 | 0.024 | 0.3321 | No |
| 20 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 5797 | 0.017 | 0.3046 | No |
| 21 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 5886 | 0.016 | 0.3020 | No |
| 22 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6175 | 0.012 | 0.2832 | No |
| 23 | SPARCL1 | SPARCL1 Entrez, Source | SPARC-like 1 (mast9, hevin) | 8609 | -0.025 | 0.1066 | No |
| 24 | VEGFB | VEGFB Entrez, Source | vascular endothelial growth factor B | 8955 | -0.031 | 0.0885 | No |
| 25 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 9244 | -0.037 | 0.0760 | No |
| 26 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 9450 | -0.041 | 0.0706 | No |
| 27 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 9982 | -0.052 | 0.0436 | No |
| 28 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 10637 | -0.068 | 0.0113 | No |
| 29 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12472 | -0.167 | -0.0851 | No |
| 30 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 13012 | -0.297 | -0.0520 | No |
| 31 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 13034 | -0.309 | 0.0231 | No |
