Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | AMINO_ACID_CATABOLIC_PROCESS |
| Enrichment Score (ES) | 0.6243483 |
| Normalized Enrichment Score (NES) | 1.7012008 |
| Nominal p-value | 0.004385965 |
| FDR q-value | 0.036221396 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 110 | 0.403 | 0.1011 | Yes |
| 2 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 126 | 0.385 | 0.2047 | Yes |
| 3 | ARG1 | ARG1 Entrez, Source | arginase, liver | 145 | 0.358 | 0.3007 | Yes |
| 4 | ASL | ASL Entrez, Source | argininosuccinate lyase | 183 | 0.323 | 0.3858 | Yes |
| 5 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 219 | 0.299 | 0.4645 | Yes |
| 6 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 651 | 0.179 | 0.4808 | Yes |
| 7 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 662 | 0.178 | 0.5285 | Yes |
| 8 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 816 | 0.161 | 0.5607 | Yes |
| 9 | BCKDK | BCKDK Entrez, Source | branched chain ketoacid dehydrogenase kinase | 868 | 0.156 | 0.5992 | Yes |
| 10 | AMT | AMT Entrez, Source | aminomethyltransferase | 1397 | 0.119 | 0.5918 | Yes |
| 11 | ASRGL1 | ASRGL1 Entrez, Source | asparaginase like 1 | 1612 | 0.108 | 0.6052 | Yes |
| 12 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 1733 | 0.104 | 0.6243 | Yes |
| 13 | MCCC2 | MCCC2 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 3517 | 0.056 | 0.5056 | No |
| 14 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 4162 | 0.044 | 0.4691 | No |
| 15 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.4634 | No |
| 16 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 5087 | 0.028 | 0.4182 | No |
| 17 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 5916 | 0.015 | 0.3602 | No |
| 18 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 9012 | -0.032 | 0.1367 | No |
| 19 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 10797 | -0.072 | 0.0225 | No |
| 20 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 12900 | -0.253 | -0.0666 | No |
| 21 | DDAH1 | DDAH1 Entrez, Source | dimethylarginine dimethylaminohydrolase 1 | 13118 | -0.367 | 0.0168 | No |
