Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | AROMATIC_COMPOUND_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.7260721 |
| Normalized Enrichment Score (NES) | 1.9028515 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0065031466 |
| FWER p-Value | 0.447 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 15 | 0.731 | 0.2429 | Yes |
| 2 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 126 | 0.385 | 0.3633 | Yes |
| 3 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 219 | 0.299 | 0.4563 | Yes |
| 4 | MOCS2 | MOCS2 Entrez, Source | molybdenum cofactor synthesis 2 | 352 | 0.248 | 0.5293 | Yes |
| 5 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 445 | 0.217 | 0.5949 | Yes |
| 6 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 465 | 0.211 | 0.6640 | Yes |
| 7 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 612 | 0.184 | 0.7146 | Yes |
| 8 | SULT1B1 | SULT1B1 Entrez, Source | sulfotransferase family, cytosolic, 1B, member 1 | 1102 | 0.137 | 0.7235 | Yes |
| 9 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 1560 | 0.110 | 0.7261 | Yes |
| 10 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 2407 | 0.082 | 0.6900 | No |
| 11 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 3595 | 0.054 | 0.6189 | No |
| 12 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4383 | 0.040 | 0.5731 | No |
| 13 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6821 | 0.002 | 0.3910 | No |
| 14 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 8385 | -0.021 | 0.2808 | No |
| 15 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 9012 | -0.032 | 0.2447 | No |
| 16 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 9268 | -0.037 | 0.2379 | No |
| 17 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 10730 | -0.071 | 0.1519 | No |
| 18 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | 0.0923 | No |
