Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | ATRIA_UP |
| Enrichment Score (ES) | -0.52139145 |
| Normalized Enrichment Score (NES) | -1.889844 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02198347 |
| FWER p-Value | 0.637 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FGFR2 | FGFR2 Entrez, Source | ffer syndrome, Jackson-Weiss syndrome) | 84 | 0.431 | 0.0204 | No |
| 2 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 322 | 0.259 | 0.0186 | No |
| 3 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 467 | 0.211 | 0.0207 | No |
| 4 | HYOU1 | HYOU1 Entrez, Source | hypoxia up-regulated 1 | 540 | 0.194 | 0.0274 | No |
| 5 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.0179 | No |
| 6 | SLC39A8 | SLC39A8 Entrez, Source | solute carrier family 39 (zinc transporter), member 8 | 969 | 0.148 | 0.0143 | No |
| 7 | DGKZ | DGKZ Entrez, Source | diacylglycerol kinase, zeta 104kDa | 990 | 0.146 | 0.0218 | No |
| 8 | FMOD | FMOD Entrez, Source | fibromodulin | 1105 | 0.137 | 0.0217 | No |
| 9 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 1390 | 0.119 | 0.0076 | No |
| 10 | MIPEP | MIPEP Entrez, Source | mitochondrial intermediate peptidase | 1455 | 0.116 | 0.0099 | No |
| 11 | RARRES2 | RARRES2 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 2 | 1501 | 0.113 | 0.0135 | No |
| 12 | GNB5 | GNB5 Entrez, Source | guanine nucleotide binding protein (G protein), beta 5 | 1559 | 0.110 | 0.0161 | No |
| 13 | FEV | FEV Entrez, Source | FEV (ETS oncogene family) | 1641 | 0.107 | 0.0166 | No |
| 14 | KDELR2 | KDELR2 Entrez, Source | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 2086 | 0.091 | -0.0113 | No |
| 15 | CHRNE | CHRNE Entrez, Source | cholinergic receptor, nicotinic, epsilon | 2170 | 0.089 | -0.0121 | No |
| 16 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 2189 | 0.088 | -0.0080 | No |
| 17 | TBX5 | TBX5 Entrez, Source | T-box 5 | 2299 | 0.085 | -0.0109 | No |
| 18 | C10ORF7 | C10ORF7 Entrez, Source | chromosome 10 open reading frame 7 | 2355 | 0.084 | -0.0099 | No |
| 19 | CALR | CALR Entrez, Source | calreticulin | 2497 | 0.080 | -0.0156 | No |
| 20 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 2640 | 0.075 | -0.0217 | No |
| 21 | AGTR1 | AGTR1 Entrez, Source | angiotensin II receptor, type 1 | 2934 | 0.068 | -0.0397 | No |
| 22 | PLA2G5 | PLA2G5 Entrez, Source | phospholipase A2, group V | 3301 | 0.060 | -0.0636 | No |
| 23 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 3465 | 0.057 | -0.0725 | No |
| 24 | TMED3 | TMED3 Entrez, Source | transmembrane emp24 protein transport domain containing 3 | 3590 | 0.054 | -0.0785 | No |
| 25 | SFRP1 | SFRP1 Entrez, Source | secreted frizzled-related protein 1 | 3641 | 0.053 | -0.0790 | No |
| 26 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 3728 | 0.051 | -0.0823 | No |
| 27 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3797 | 0.050 | -0.0844 | No |
| 28 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 3840 | 0.049 | -0.0845 | No |
| 29 | SLC22A18 | SLC22A18 Entrez, Source | solute carrier family 22 (organic cation transporter), member 18 | 3870 | 0.049 | -0.0837 | No |
| 30 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 3951 | 0.047 | -0.0868 | No |
| 31 | SLIT3 | SLIT3 Entrez, Source | slit homolog 3 (Drosophila) | 4012 | 0.046 | -0.0885 | No |
| 32 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 4028 | 0.046 | -0.0867 | No |
| 33 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 4357 | 0.040 | -0.1091 | No |
| 34 | PPIB | PPIB Entrez, Source | peptidylprolyl isomerase B (cyclophilin B) | 4455 | 0.039 | -0.1140 | No |
| 35 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 5235 | 0.026 | -0.1714 | No |
| 36 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 5277 | 0.025 | -0.1730 | No |
| 37 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 5391 | 0.023 | -0.1801 | No |
| 38 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 5520 | 0.021 | -0.1884 | No |
| 39 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 5539 | 0.021 | -0.1885 | No |
| 40 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 5594 | 0.020 | -0.1913 | No |
| 41 | DHODH | DHODH Entrez, Source | dihydroorotate dehydrogenase | 5933 | 0.015 | -0.2159 | No |
| 42 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 6054 | 0.013 | -0.2242 | No |
| 43 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6191 | 0.011 | -0.2338 | No |
| 44 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 6316 | 0.009 | -0.2426 | No |
| 45 | SMARCD2 | SMARCD2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 6323 | 0.009 | -0.2425 | No |
| 46 | SLN | SLN Entrez, Source | sarcolipin | 6350 | 0.009 | -0.2439 | No |
| 47 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 6635 | 0.005 | -0.2651 | No |
| 48 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 6721 | 0.004 | -0.2713 | No |
| 49 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 6725 | 0.004 | -0.2713 | No |
| 50 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 6773 | 0.003 | -0.2747 | No |
| 51 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 6851 | 0.002 | -0.2804 | No |
| 52 | CELSR2 | CELSR2 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | 7056 | -0.001 | -0.2958 | No |
| 53 | TOR1A | TOR1A Entrez, Source | torsin family 1, member A (torsin A) | 7125 | -0.002 | -0.3008 | No |
| 54 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 7127 | -0.002 | -0.3007 | No |
| 55 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 7135 | -0.002 | -0.3011 | No |
| 56 | SOD3 | SOD3 Entrez, Source | superoxide dismutase 3, extracellular | 7289 | -0.004 | -0.3124 | No |
| 57 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7318 | -0.005 | -0.3143 | No |
| 58 | NRTN | NRTN Entrez, Source | neurturin | 7360 | -0.005 | -0.3170 | No |
| 59 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 7381 | -0.006 | -0.3182 | No |
| 60 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7382 | -0.006 | -0.3178 | No |
| 61 | TMEM106C | TMEM106C Entrez, Source | transmembrane protein 106C | 7383 | -0.006 | -0.3175 | No |
| 62 | GRIN2C | GRIN2C Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 7491 | -0.007 | -0.3251 | No |
| 63 | INPP1 | INPP1 Entrez, Source | inositol polyphosphate-1-phosphatase | 7518 | -0.008 | -0.3266 | No |
| 64 | FEZ1 | FEZ1 Entrez, Source | fasciculation and elongation protein zeta 1 (zygin I) | 7623 | -0.009 | -0.3339 | No |
| 65 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 7659 | -0.010 | -0.3359 | No |
| 66 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 7716 | -0.011 | -0.3395 | No |
| 67 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 7727 | -0.011 | -0.3396 | No |
| 68 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 8175 | -0.018 | -0.3723 | No |
| 69 | PDE8B | PDE8B Entrez, Source | phosphodiesterase 8B | 8180 | -0.018 | -0.3716 | No |
| 70 | AFAP | AFAP Entrez, Source | - | 8351 | -0.021 | -0.3831 | No |
| 71 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 8618 | -0.025 | -0.4017 | No |
| 72 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 8736 | -0.027 | -0.4089 | No |
| 73 | KCNA5 | KCNA5 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 5 | 8781 | -0.028 | -0.4105 | No |
| 74 | CADPS | CADPS Entrez, Source | Ca2+-dependent secretion activator | 8796 | -0.028 | -0.4098 | No |
| 75 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 9166 | -0.035 | -0.4356 | No |
| 76 | FRMD4B | FRMD4B Entrez, Source | FERM domain containing 4B | 9272 | -0.037 | -0.4412 | No |
| 77 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 9564 | -0.043 | -0.4606 | No |
| 78 | SYNPO | SYNPO Entrez, Source | synaptopodin | 9931 | -0.051 | -0.4851 | No |
| 79 | USP11 | USP11 Entrez, Source | ubiquitin specific peptidase 11 | 10045 | -0.053 | -0.4904 | No |
| 80 | PLOD3 | PLOD3 Entrez, Source | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 10122 | -0.055 | -0.4927 | No |
| 81 | WISP2 | WISP2 Entrez, Source | WNT1 inducible signaling pathway protein 2 | 10285 | -0.059 | -0.5013 | No |
| 82 | PLXNB2 | PLXNB2 Entrez, Source | plexin B2 | 10304 | -0.059 | -0.4990 | No |
| 83 | DAPK2 | DAPK2 Entrez, Source | death-associated protein kinase 2 | 10332 | -0.060 | -0.4974 | No |
| 84 | PDE2A | PDE2A Entrez, Source | phosphodiesterase 2A, cGMP-stimulated | 10423 | -0.062 | -0.5003 | No |
| 85 | PTHR1 | PTHR1 Entrez, Source | parathyroid hormone receptor 1 | 10494 | -0.064 | -0.5016 | No |
| 86 | VSNL1 | VSNL1 Entrez, Source | visinin-like 1 | 10633 | -0.068 | -0.5079 | No |
| 87 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 10788 | -0.072 | -0.5150 | No |
| 88 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 10834 | -0.073 | -0.5139 | No |
| 89 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 10934 | -0.076 | -0.5166 | Yes |
| 90 | MAGED1 | MAGED1 Entrez, Source | melanoma antigen family D, 1 | 10946 | -0.077 | -0.5127 | Yes |
| 91 | CREB3L2 | CREB3L2 Entrez, Source | cAMP responsive element binding protein 3-like 2 | 10974 | -0.078 | -0.5099 | Yes |
| 92 | CD81 | CD81 Entrez, Source | CD81 molecule | 11022 | -0.079 | -0.5086 | Yes |
| 93 | RABAC1 | RABAC1 Entrez, Source | Rab acceptor 1 (prenylated) | 11046 | -0.080 | -0.5053 | Yes |
| 94 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 11225 | -0.087 | -0.5134 | Yes |
| 95 | TNK2 | TNK2 Entrez, Source | tyrosine kinase, non-receptor, 2 | 11259 | -0.089 | -0.5104 | Yes |
| 96 | FBLN2 | FBLN2 Entrez, Source | fibulin 2 | 11361 | -0.093 | -0.5123 | Yes |
| 97 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 11377 | -0.094 | -0.5076 | Yes |
| 98 | VAMP5 | VAMP5 Entrez, Source | vesicle-associated membrane protein 5 (myobrevin) | 11394 | -0.095 | -0.5029 | Yes |
| 99 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 11551 | -0.102 | -0.5084 | Yes |
| 100 | NTRK2 | NTRK2 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 2 | 11666 | -0.108 | -0.5103 | Yes |
| 101 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 11712 | -0.110 | -0.5069 | Yes |
| 102 | DAP | DAP Entrez, Source | death-associated protein | 11716 | -0.110 | -0.5003 | Yes |
| 103 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 11764 | -0.112 | -0.4969 | Yes |
| 104 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 11817 | -0.115 | -0.4938 | Yes |
| 105 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 11878 | -0.118 | -0.4910 | Yes |
| 106 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 12170 | -0.136 | -0.5046 | Yes |
| 107 | PLCB1 | PLCB1 Entrez, Source | phospholipase C, beta 1 (phosphoinositide-specific) | 12183 | -0.138 | -0.4969 | Yes |
| 108 | PIP5K2B | PIP5K2B Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type II, beta | 12221 | -0.142 | -0.4909 | Yes |
| 109 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 12233 | -0.142 | -0.4829 | Yes |
| 110 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 12254 | -0.144 | -0.4755 | Yes |
| 111 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12303 | -0.149 | -0.4699 | Yes |
| 112 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 12355 | -0.153 | -0.4643 | Yes |
| 113 | SGCE | SGCE Entrez, Source | sarcoglycan, epsilon | 12368 | -0.155 | -0.4556 | Yes |
| 114 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.4573 | Yes |
| 115 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12631 | -0.190 | -0.4526 | Yes |
| 116 | CD47 | CD47 Entrez, Source | CD47 molecule | 12700 | -0.205 | -0.4450 | Yes |
| 117 | VAT1 | VAT1 Entrez, Source | vesicle amine transport protein 1 homolog (T californica) | 12754 | -0.214 | -0.4357 | Yes |
| 118 | CRMP1 | CRMP1 Entrez, Source | collapsin response mediator protein 1 | 12762 | -0.215 | -0.4229 | Yes |
| 119 | CTSF | CTSF Entrez, Source | cathepsin F | 12787 | -0.221 | -0.4110 | Yes |
| 120 | GRN | GRN Entrez, Source | granulin | 12966 | -0.278 | -0.4072 | Yes |
| 121 | RELN | RELN Entrez, Source | reelin | 12968 | -0.279 | -0.3900 | Yes |
| 122 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 12978 | -0.283 | -0.3731 | Yes |
| 123 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 13095 | -0.352 | -0.3600 | Yes |
| 124 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 13112 | -0.366 | -0.3385 | Yes |
| 125 | DPYSL3 | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 13155 | -0.408 | -0.3164 | Yes |
| 126 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 13160 | -0.412 | -0.2910 | Yes |
| 127 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 13219 | -0.495 | -0.2647 | Yes |
| 128 | IL1RL1 | IL1RL1 Entrez, Source | interleukin 1 receptor-like 1 | 13223 | -0.499 | -0.2340 | Yes |
| 129 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13260 | -0.571 | -0.2012 | Yes |
| 130 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13266 | -0.607 | -0.1639 | Yes |
| 131 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | -0.1242 | Yes |
| 132 | ADM | ADM Entrez, Source | adrenomedullin | 13287 | -0.697 | -0.0814 | Yes |
| 133 | CPE | CPE Entrez, Source | carboxypeptidase E | 13337 | -1.377 | 0.0004 | Yes |
