Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | BAF57_BT549_UP |
| Enrichment Score (ES) | -0.50089276 |
| Normalized Enrichment Score (NES) | -1.8037316 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03672624 |
| FWER p-Value | 0.96 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 115 | 0.397 | 0.0115 | No |
| 2 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 239 | 0.290 | 0.0169 | No |
| 3 | GHR | GHR Entrez, Source | growth hormone receptor | 250 | 0.287 | 0.0307 | No |
| 4 | MAFB | MAFB Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 285 | 0.273 | 0.0421 | No |
| 5 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 303 | 0.265 | 0.0543 | No |
| 6 | LIFR | LIFR Entrez, Source | leukemia inhibitory factor receptor alpha | 339 | 0.253 | 0.0644 | No |
| 7 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 355 | 0.248 | 0.0759 | No |
| 8 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 358 | 0.245 | 0.0882 | No |
| 9 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 391 | 0.235 | 0.0977 | No |
| 10 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 445 | 0.217 | 0.1048 | No |
| 11 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 635 | 0.182 | 0.0997 | No |
| 12 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.0955 | No |
| 13 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 817 | 0.161 | 0.1025 | No |
| 14 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 875 | 0.155 | 0.1061 | No |
| 15 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 950 | 0.149 | 0.1081 | No |
| 16 | MGP | MGP Entrez, Source | matrix Gla protein | 1003 | 0.144 | 0.1115 | No |
| 17 | PRSS35 | PRSS35 Entrez, Source | protease, serine, 35 | 1104 | 0.137 | 0.1108 | No |
| 18 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 1150 | 0.133 | 0.1142 | No |
| 19 | CFI | CFI Entrez, Source | complement factor I | 1261 | 0.126 | 0.1123 | No |
| 20 | SLC44A1 | SLC44A1 Entrez, Source | solute carrier family 44, member 1 | 1379 | 0.120 | 0.1095 | No |
| 21 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 1617 | 0.108 | 0.0971 | No |
| 22 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 1619 | 0.108 | 0.1025 | No |
| 23 | GABBR2 | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 1650 | 0.107 | 0.1057 | No |
| 24 | GULP1 | GULP1 Entrez, Source | GULP, engulfment adaptor PTB domain containing 1 | 1862 | 0.099 | 0.0947 | No |
| 25 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1863 | 0.099 | 0.0997 | No |
| 26 | SLC12A8 | SLC12A8 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 8 | 1950 | 0.095 | 0.0981 | No |
| 27 | IRS1 | IRS1 Entrez, Source | insulin receptor substrate 1 | 2329 | 0.084 | 0.0737 | No |
| 28 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 2539 | 0.078 | 0.0619 | No |
| 29 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 2628 | 0.076 | 0.0591 | No |
| 30 | FZD1 | FZD1 Entrez, Source | frizzled homolog 1 (Drosophila) | 2630 | 0.076 | 0.0629 | No |
| 31 | KLRC2 | KLRC2 Entrez, Source | killer cell lectin-like receptor subfamily C, member 2 | 2776 | 0.072 | 0.0555 | No |
| 32 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 2944 | 0.068 | 0.0463 | No |
| 33 | GAS5 | GAS5 Entrez, Source | growth arrest-specific 5 | 2986 | 0.067 | 0.0466 | No |
| 34 | ANTXR1 | ANTXR1 Entrez, Source | anthrax toxin receptor 1 | 3443 | 0.057 | 0.0150 | No |
| 35 | CTHRC1 | CTHRC1 Entrez, Source | collagen triple helix repeat containing 1 | 3598 | 0.054 | 0.0061 | No |
| 36 | IL13RA1 | IL13RA1 Entrez, Source | interleukin 13 receptor, alpha 1 | 3674 | 0.052 | 0.0031 | No |
| 37 | CA4 | CA4 Entrez, Source | carbonic anhydrase IV | 3716 | 0.052 | 0.0026 | No |
| 38 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 3728 | 0.051 | 0.0044 | No |
| 39 | COPS8 | COPS8 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 3778 | 0.050 | 0.0032 | No |
| 40 | AGC1 | AGC1 Entrez, Source | aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) | 3843 | 0.049 | 0.0009 | No |
| 41 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4057 | 0.045 | -0.0130 | No |
| 42 | PAK3 | PAK3 Entrez, Source | p21 (CDKN1A)-activated kinase 3 | 4254 | 0.042 | -0.0257 | No |
| 43 | OXTR | OXTR Entrez, Source | oxytocin receptor | 4362 | 0.040 | -0.0317 | No |
| 44 | BTD | BTD Entrez, Source | biotinidase | 4657 | 0.035 | -0.0522 | No |
| 45 | PRRX1 | PRRX1 Entrez, Source | paired related homeobox 1 | 4754 | 0.033 | -0.0578 | No |
| 46 | AVIL | AVIL Entrez, Source | advillin | 5268 | 0.025 | -0.0953 | No |
| 47 | WT1 | WT1 Entrez, Source | Wilms tumor 1 | 5408 | 0.023 | -0.1047 | No |
| 48 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 5539 | 0.021 | -0.1135 | No |
| 49 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 5594 | 0.020 | -0.1165 | No |
| 50 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 5633 | 0.020 | -0.1184 | No |
| 51 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 5846 | 0.017 | -0.1336 | No |
| 52 | SOCS3 | SOCS3 Entrez, Source | suppressor of cytokine signaling 3 | 6099 | 0.013 | -0.1520 | No |
| 53 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 6244 | 0.011 | -0.1624 | No |
| 54 | PARVA | PARVA Entrez, Source | parvin, alpha | 6285 | 0.010 | -0.1649 | No |
| 55 | RPL37 | RPL37 Entrez, Source | ribosomal protein L37 | 6404 | 0.008 | -0.1734 | No |
| 56 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 6461 | 0.007 | -0.1773 | No |
| 57 | UNC5B | UNC5B Entrez, Source | unc-5 homolog B (C. elegans) | 6609 | 0.005 | -0.1882 | No |
| 58 | STRBP | STRBP Entrez, Source | spermatid perinuclear RNA binding protein | 6648 | 0.005 | -0.1908 | No |
| 59 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 7002 | -0.000 | -0.2175 | No |
| 60 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 7132 | -0.002 | -0.2272 | No |
| 61 | NAP1L3 | NAP1L3 Entrez, Source | nucleosome assembly protein 1-like 3 | 7169 | -0.003 | -0.2298 | No |
| 62 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 7631 | -0.010 | -0.2642 | No |
| 63 | CD200 | CD200 Entrez, Source | CD200 molecule | 7661 | -0.010 | -0.2659 | No |
| 64 | SLC22A17 | SLC22A17 Entrez, Source | solute carrier family 22 (organic cation transporter), member 17 | 7753 | -0.011 | -0.2722 | No |
| 65 | NID1 | NID1 Entrez, Source | nidogen 1 | 7761 | -0.011 | -0.2721 | No |
| 66 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 7827 | -0.013 | -0.2764 | No |
| 67 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 8231 | -0.019 | -0.3060 | No |
| 68 | SERPINB7 | SERPINB7 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | 8257 | -0.019 | -0.3069 | No |
| 69 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 8308 | -0.020 | -0.3097 | No |
| 70 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 8539 | -0.024 | -0.3259 | No |
| 71 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 8587 | -0.025 | -0.3282 | No |
| 72 | DCN | DCN Entrez, Source | decorin | 8600 | -0.025 | -0.3278 | No |
| 73 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 8618 | -0.025 | -0.3279 | No |
| 74 | STOM | STOM Entrez, Source | stomatin | 8714 | -0.027 | -0.3337 | No |
| 75 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 8843 | -0.029 | -0.3419 | No |
| 76 | SIPA1L1 | SIPA1L1 Entrez, Source | signal-induced proliferation-associated 1 like 1 | 8860 | -0.029 | -0.3417 | No |
| 77 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 9235 | -0.036 | -0.3681 | No |
| 78 | DIO2 | DIO2 Entrez, Source | deiodinase, iodothyronine, type II | 9834 | -0.049 | -0.4109 | No |
| 79 | CYBRD1 | CYBRD1 Entrez, Source | cytochrome b reductase 1 | 9887 | -0.050 | -0.4123 | No |
| 80 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 9978 | -0.052 | -0.4165 | No |
| 81 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 10011 | -0.052 | -0.4163 | No |
| 82 | FN1 | FN1 Entrez, Source | fibronectin 1 | 10062 | -0.053 | -0.4174 | No |
| 83 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 10092 | -0.054 | -0.4168 | No |
| 84 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 10363 | -0.061 | -0.4342 | No |
| 85 | SERPINB3 | SERPINB3 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 10469 | -0.064 | -0.4389 | No |
| 86 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 10717 | -0.070 | -0.4540 | No |
| 87 | SULF2 | SULF2 Entrez, Source | sulfatase 2 | 10768 | -0.072 | -0.4542 | No |
| 88 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 10788 | -0.072 | -0.4519 | No |
| 89 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 10801 | -0.073 | -0.4491 | No |
| 90 | COL12A1 | COL12A1 Entrez, Source | collagen, type XII, alpha 1 | 10811 | -0.073 | -0.4461 | No |
| 91 | ZBTB1 | ZBTB1 Entrez, Source | zinc finger and BTB domain containing 1 | 10948 | -0.077 | -0.4525 | No |
| 92 | BACE2 | BACE2 Entrez, Source | beta-site APP-cleaving enzyme 2 | 10980 | -0.078 | -0.4509 | No |
| 93 | FNDC1 | FNDC1 Entrez, Source | fibronectin type III domain containing 1 | 11008 | -0.079 | -0.4489 | No |
| 94 | SIPA1L2 | SIPA1L2 Entrez, Source | signal-induced proliferation-associated 1 like 2 | 11018 | -0.079 | -0.4456 | No |
| 95 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 11431 | -0.096 | -0.4719 | No |
| 96 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 11649 | -0.107 | -0.4829 | No |
| 97 | NTRK2 | NTRK2 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 2 | 11666 | -0.108 | -0.4786 | No |
| 98 | BCAM | BCAM Entrez, Source | basal cell adhesion molecule (Lutheran blood group) | 11705 | -0.109 | -0.4759 | No |
| 99 | LUM | LUM Entrez, Source | lumican | 11773 | -0.112 | -0.4753 | No |
| 100 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | -0.4942 | Yes |
| 101 | THEX1 | THEX1 Entrez, Source | three prime histone mRNA exonuclease 1 | 12135 | -0.133 | -0.4891 | Yes |
| 102 | BMPR2 | BMPR2 Entrez, Source | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 12152 | -0.135 | -0.4834 | Yes |
| 103 | CASK | CASK Entrez, Source | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 12154 | -0.135 | -0.4767 | Yes |
| 104 | PLSCR4 | PLSCR4 Entrez, Source | phospholipid scramblase 4 | 12219 | -0.141 | -0.4743 | Yes |
| 105 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 12264 | -0.145 | -0.4703 | Yes |
| 106 | PLAG1 | PLAG1 Entrez, Source | pleiomorphic adenoma gene 1 | 12351 | -0.153 | -0.4690 | Yes |
| 107 | SMTN | SMTN Entrez, Source | smoothelin | 12423 | -0.161 | -0.4662 | Yes |
| 108 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12472 | -0.167 | -0.4613 | Yes |
| 109 | POU3F3 | POU3F3 Entrez, Source | POU domain, class 3, transcription factor 3 | 12510 | -0.172 | -0.4554 | Yes |
| 110 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.4484 | Yes |
| 111 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | -0.4396 | Yes |
| 112 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 12594 | -0.184 | -0.4342 | Yes |
| 113 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 12615 | -0.187 | -0.4262 | Yes |
| 114 | TCEAL8 | TCEAL8 Entrez, Source | transcription elongation factor A (SII)-like 8 | 12618 | -0.187 | -0.4169 | Yes |
| 115 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12690 | -0.203 | -0.4119 | Yes |
| 116 | PTGFRN | PTGFRN Entrez, Source | prostaglandin F2 receptor negative regulator | 12701 | -0.205 | -0.4023 | Yes |
| 117 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12813 | -0.228 | -0.3991 | Yes |
| 118 | RAB27A | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 12927 | -0.261 | -0.3943 | Yes |
| 119 | FBXO32 | FBXO32 Entrez, Source | F-box protein 32 | 12951 | -0.273 | -0.3822 | Yes |
| 120 | KLHL24 | KLHL24 Entrez, Source | kelch-like 24 (Drosophila) | 13056 | -0.323 | -0.3736 | Yes |
| 121 | DPYSL3 | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 13155 | -0.408 | -0.3603 | Yes |
| 122 | BCAT1 | BCAT1 Entrez, Source | branched chain aminotransferase 1, cytosolic | 13181 | -0.442 | -0.3397 | Yes |
| 123 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13183 | -0.443 | -0.3173 | Yes |
| 124 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 13192 | -0.458 | -0.2946 | Yes |
| 125 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13198 | -0.463 | -0.2715 | Yes |
| 126 | KITLG | KITLG Entrez, Source | KIT ligand | 13215 | -0.492 | -0.2477 | Yes |
| 127 | SERINC5 | SERINC5 Entrez, Source | serine incorporator 5 | 13225 | -0.503 | -0.2228 | Yes |
| 128 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13229 | -0.509 | -0.1972 | Yes |
| 129 | TPBG | TPBG Entrez, Source | trophoblast glycoprotein | 13238 | -0.524 | -0.1711 | Yes |
| 130 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13282 | -0.665 | -0.1406 | Yes |
| 131 | FBLIM1 | FBLIM1 Entrez, Source | filamin binding LIM protein 1 | 13284 | -0.687 | -0.1057 | Yes |
| 132 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 13306 | -0.786 | -0.0674 | Yes |
| 133 | CPE | CPE Entrez, Source | carboxypeptidase E | 13337 | -1.377 | 0.0004 | Yes |
