Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | BASSO_HCL_DIFF |
| Enrichment Score (ES) | -0.6530577 |
| Normalized Enrichment Score (NES) | -1.9942884 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0065248846 |
| FWER p-Value | 0.173 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 303 | 0.265 | 0.0150 | No |
| 2 | RCBTB2 | RCBTB2 Entrez, Source | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 796 | 0.163 | 0.0013 | No |
| 3 | GAS7 | GAS7 Entrez, Source | growth arrest-specific 7 | 1442 | 0.116 | -0.0307 | No |
| 4 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 1483 | 0.114 | -0.0174 | No |
| 5 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 2261 | 0.086 | -0.0636 | No |
| 6 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 2639 | 0.075 | -0.0812 | No |
| 7 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 3018 | 0.066 | -0.1002 | No |
| 8 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 3063 | 0.065 | -0.0942 | No |
| 9 | ENG | ENG Entrez, Source | endoglin (Osler-Rendu-Weber syndrome 1) | 3072 | 0.065 | -0.0856 | No |
| 10 | BLR1 | BLR1 Entrez, Source | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | 3382 | 0.058 | -0.1005 | No |
| 11 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 4030 | 0.046 | -0.1426 | No |
| 12 | PDE4DIP | PDE4DIP Entrez, Source | phosphodiesterase 4D interacting protein (myomegalin) | 4349 | 0.040 | -0.1608 | No |
| 13 | TBKBP1 | TBKBP1 Entrez, Source | TBK1 binding protein 1 | 4698 | 0.034 | -0.1821 | No |
| 14 | SDC3 | SDC3 Entrez, Source | syndecan 3 (N-syndecan) | 4748 | 0.034 | -0.1810 | No |
| 15 | SIX3 | SIX3 Entrez, Source | sine oculis homeobox homolog 3 (Drosophila) | 4873 | 0.031 | -0.1858 | No |
| 16 | HBB | HBB Entrez, Source | hemoglobin, beta | 5557 | 0.021 | -0.2342 | No |
| 17 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 5953 | 0.015 | -0.2618 | No |
| 18 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6041 | 0.014 | -0.2664 | No |
| 19 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 6614 | 0.005 | -0.3087 | No |
| 20 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 6937 | 0.001 | -0.3328 | No |
| 21 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 7115 | -0.002 | -0.3459 | No |
| 22 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 7500 | -0.007 | -0.3737 | No |
| 23 | RTN2 | RTN2 Entrez, Source | reticulon 2 | 8156 | -0.017 | -0.4205 | No |
| 24 | GABARAPL2 | GABARAPL2 Entrez, Source | GABA(A) receptor-associated protein-like 2 | 8493 | -0.023 | -0.4425 | No |
| 25 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 8618 | -0.025 | -0.4483 | No |
| 26 | VAMP3 | VAMP3 Entrez, Source | vesicle-associated membrane protein 3 (cellubrevin) | 9280 | -0.037 | -0.4927 | No |
| 27 | B2M | B2M Entrez, Source | beta-2-microglobulin | 9941 | -0.051 | -0.5350 | No |
| 28 | IL3RA | IL3RA Entrez, Source | interleukin 3 receptor, alpha (low affinity) | 9945 | -0.051 | -0.5280 | No |
| 29 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 11246 | -0.088 | -0.6133 | No |
| 30 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 11723 | -0.110 | -0.6334 | No |
| 31 | MYF6 | MYF6 Entrez, Source | myogenic factor 6 (herculin) | 11986 | -0.124 | -0.6354 | Yes |
| 32 | CD63 | CD63 Entrez, Source | CD63 molecule | 12132 | -0.133 | -0.6273 | Yes |
| 33 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 12264 | -0.145 | -0.6165 | Yes |
| 34 | RAB13 | RAB13 Entrez, Source | RAB13, member RAS oncogene family | 12265 | -0.145 | -0.5958 | Yes |
| 35 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 12294 | -0.147 | -0.5769 | Yes |
| 36 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 12490 | -0.169 | -0.5675 | Yes |
| 37 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 12553 | -0.179 | -0.5467 | Yes |
| 38 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 12559 | -0.179 | -0.5215 | Yes |
| 39 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 12579 | -0.181 | -0.4971 | Yes |
| 40 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 12659 | -0.196 | -0.4751 | Yes |
| 41 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 12812 | -0.228 | -0.4541 | Yes |
| 42 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13085 | -0.343 | -0.4257 | Yes |
| 43 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 13109 | -0.363 | -0.3757 | Yes |
| 44 | TACC1 | TACC1 Entrez, Source | transforming, acidic coiled-coil containing protein 1 | 13123 | -0.377 | -0.3230 | Yes |
| 45 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13193 | -0.458 | -0.2629 | Yes |
| 46 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 13276 | -0.650 | -0.1764 | Yes |
| 47 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | 0.0005 | Yes |
