Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | BRCA1_MES_UP |
| Enrichment Score (ES) | -0.7502541 |
| Normalized Enrichment Score (NES) | -2.1125524 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0012372183 |
| FWER p-Value | 0.018 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 1177 | 0.132 | -0.0616 | No |
| 2 | FGFBP1 | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 1310 | 0.124 | -0.0463 | No |
| 3 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 2759 | 0.072 | -0.1403 | No |
| 4 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 3875 | 0.049 | -0.2142 | No |
| 5 | DDX24 | DDX24 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 | 5739 | 0.018 | -0.3504 | No |
| 6 | EIF3S8 | EIF3S8 Entrez, Source | eukaryotic translation initiation factor 3, subunit 8, 110kDa | 5936 | 0.015 | -0.3620 | No |
| 7 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 5943 | 0.015 | -0.3594 | No |
| 8 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6041 | 0.014 | -0.3639 | No |
| 9 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 6150 | 0.012 | -0.3696 | No |
| 10 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 6818 | 0.002 | -0.4192 | No |
| 11 | DLG1 | DLG1 Entrez, Source | discs, large homolog 1 (Drosophila) | 6958 | 0.000 | -0.4296 | No |
| 12 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 7159 | -0.002 | -0.4441 | No |
| 13 | ARF1 | ARF1 Entrez, Source | ADP-ribosylation factor 1 | 7639 | -0.010 | -0.4781 | No |
| 14 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 7686 | -0.010 | -0.4795 | No |
| 15 | NUMB | NUMB Entrez, Source | numb homolog (Drosophila) | 7901 | -0.014 | -0.4928 | No |
| 16 | ATP6AP1 | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 8294 | -0.020 | -0.5182 | No |
| 17 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 9325 | -0.038 | -0.5878 | No |
| 18 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 9558 | -0.043 | -0.5965 | No |
| 19 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 9691 | -0.045 | -0.5972 | No |
| 20 | LXN | LXN Entrez, Source | latexin | 11080 | -0.081 | -0.6849 | No |
| 21 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11124 | -0.083 | -0.6713 | No |
| 22 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 12119 | -0.132 | -0.7189 | Yes |
| 23 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.7143 | Yes |
| 24 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 12692 | -0.203 | -0.6844 | Yes |
| 25 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12706 | -0.206 | -0.6435 | Yes |
| 26 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.6058 | Yes |
| 27 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13035 | -0.310 | -0.5443 | Yes |
| 28 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13069 | -0.331 | -0.4793 | Yes |
| 29 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.3934 | Yes |
| 30 | VIM | VIM Entrez, Source | vimentin | 13227 | -0.506 | -0.2920 | Yes |
| 31 | TAGLN | TAGLN Entrez, Source | transgelin | 13339 | -1.475 | 0.0002 | Yes |
