Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | BRCA_PROGNOSIS_NEG |
| Enrichment Score (ES) | -0.6561247 |
| Normalized Enrichment Score (NES) | -1.9332168 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.013770614 |
| FWER p-Value | 0.402 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 556 | 0.192 | -0.0108 | No |
| 2 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 608 | 0.185 | 0.0153 | No |
| 3 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 901 | 0.153 | 0.0180 | No |
| 4 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 1308 | 0.124 | 0.0075 | No |
| 5 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 2274 | 0.086 | -0.0512 | No |
| 6 | MGAT4A | MGAT4A Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 3423 | 0.058 | -0.1282 | No |
| 7 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 3595 | 0.054 | -0.1323 | No |
| 8 | NMU | NMU Entrez, Source | neuromedin U | 3853 | 0.049 | -0.1437 | No |
| 9 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 3861 | 0.049 | -0.1363 | No |
| 10 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4057 | 0.045 | -0.1437 | No |
| 11 | ASNS | ASNS Entrez, Source | asparagine synthetase | 4245 | 0.042 | -0.1509 | No |
| 12 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 4346 | 0.040 | -0.1519 | No |
| 13 | UCHL5 | UCHL5 Entrez, Source | ubiquitin carboxyl-terminal hydrolase L5 | 4673 | 0.035 | -0.1708 | No |
| 14 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 5119 | 0.027 | -0.1998 | No |
| 15 | MRPL13 | MRPL13 Entrez, Source | mitochondrial ribosomal protein L13 | 6363 | 0.008 | -0.2919 | No |
| 16 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.3372 | No |
| 17 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 7152 | -0.002 | -0.3506 | No |
| 18 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 7411 | -0.006 | -0.3690 | No |
| 19 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 7605 | -0.009 | -0.3821 | No |
| 20 | PTDSS1 | PTDSS1 Entrez, Source | phosphatidylserine synthase 1 | 7804 | -0.012 | -0.3950 | No |
| 21 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 7875 | -0.013 | -0.3981 | No |
| 22 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 7948 | -0.014 | -0.4012 | No |
| 23 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8545 | -0.024 | -0.4422 | No |
| 24 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 8584 | -0.024 | -0.4411 | No |
| 25 | MTDH | MTDH Entrez, Source | metadherin | 8941 | -0.031 | -0.4628 | No |
| 26 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 9266 | -0.037 | -0.4812 | No |
| 27 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 9831 | -0.048 | -0.5158 | No |
| 28 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 11324 | -0.092 | -0.6131 | No |
| 29 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 11568 | -0.103 | -0.6148 | No |
| 30 | AURKA | AURKA Entrez, Source | aurora kinase A | 11917 | -0.119 | -0.6216 | No |
| 31 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 12377 | -0.156 | -0.6309 | Yes |
| 32 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12437 | -0.162 | -0.6092 | Yes |
| 33 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12851 | -0.238 | -0.6017 | Yes |
| 34 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12949 | -0.272 | -0.5650 | Yes |
| 35 | SPBC25 | SPBC25 Entrez, Source | spindle pole body component 25 homolog (S. cerevisiae) | 12974 | -0.280 | -0.5214 | Yes |
| 36 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 13078 | -0.337 | -0.4746 | Yes |
| 37 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13129 | -0.381 | -0.4167 | Yes |
| 38 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13266 | -0.607 | -0.3287 | Yes |
| 39 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.2294 | Yes |
| 40 | ADM | ADM Entrez, Source | adrenomedullin | 13287 | -0.697 | -0.1181 | Yes |
| 41 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13302 | -0.755 | 0.0030 | Yes |
