Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | BRENTANI_CELL_CYCLE |
| Enrichment Score (ES) | -0.6284533 |
| Normalized Enrichment Score (NES) | -1.9496737 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.012373774 |
| FWER p-Value | 0.333 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 1140 | 0.134 | -0.0622 | No |
| 2 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | -0.0784 | No |
| 3 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1856 | 0.099 | -0.0795 | No |
| 4 | CCNH | CCNH Entrez, Source | cyclin H | 1938 | 0.096 | -0.0687 | No |
| 5 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2527 | 0.079 | -0.0991 | No |
| 6 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 2560 | 0.078 | -0.0879 | No |
| 7 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2746 | 0.073 | -0.0891 | No |
| 8 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2765 | 0.072 | -0.0777 | No |
| 9 | POLR3D | POLR3D Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa | 3502 | 0.056 | -0.1233 | No |
| 10 | CCNF | CCNF Entrez, Source | cyclin F | 4623 | 0.036 | -0.2013 | No |
| 11 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 4648 | 0.035 | -0.1969 | No |
| 12 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6158 | 0.012 | -0.3083 | No |
| 13 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 6164 | 0.012 | -0.3066 | No |
| 14 | MOS | MOS Entrez, Source | v-mos Moloney murine sarcoma viral oncogene homolog | 6472 | 0.007 | -0.3285 | No |
| 15 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 6717 | 0.004 | -0.3463 | No |
| 16 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 6755 | 0.003 | -0.3485 | No |
| 17 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 7074 | -0.001 | -0.3722 | No |
| 18 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 7418 | -0.006 | -0.3969 | No |
| 19 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 7727 | -0.011 | -0.4182 | No |
| 20 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 8216 | -0.018 | -0.4517 | No |
| 21 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8319 | -0.020 | -0.4558 | No |
| 22 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 8462 | -0.022 | -0.4626 | No |
| 23 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 8998 | -0.032 | -0.4972 | No |
| 24 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 9270 | -0.037 | -0.5111 | No |
| 25 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 9519 | -0.042 | -0.5223 | No |
| 26 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 9556 | -0.043 | -0.5176 | No |
| 27 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 9869 | -0.049 | -0.5324 | No |
| 28 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 9949 | -0.051 | -0.5294 | No |
| 29 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 10008 | -0.052 | -0.5246 | No |
| 30 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 10726 | -0.071 | -0.5662 | No |
| 31 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 11555 | -0.102 | -0.6106 | Yes |
| 32 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 11712 | -0.110 | -0.6031 | Yes |
| 33 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11886 | -0.118 | -0.5954 | Yes |
| 34 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 11905 | -0.119 | -0.5759 | Yes |
| 35 | MAX | MAX Entrez, Source | MYC associated factor X | 11963 | -0.122 | -0.5587 | Yes |
| 36 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 11985 | -0.124 | -0.5386 | Yes |
| 37 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 12256 | -0.144 | -0.5336 | Yes |
| 38 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12272 | -0.146 | -0.5092 | Yes |
| 39 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 12376 | -0.156 | -0.4897 | Yes |
| 40 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 12377 | -0.156 | -0.4624 | Yes |
| 41 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 12406 | -0.158 | -0.4367 | Yes |
| 42 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12725 | -0.209 | -0.4240 | Yes |
| 43 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 12774 | -0.218 | -0.3894 | Yes |
| 44 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 12828 | -0.232 | -0.3527 | Yes |
| 45 | FRK | FRK Entrez, Source | fyn-related kinase | 12950 | -0.272 | -0.3141 | Yes |
| 46 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13080 | -0.340 | -0.2641 | Yes |
| 47 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13085 | -0.343 | -0.2044 | Yes |
| 48 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13131 | -0.385 | -0.1403 | Yes |
| 49 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13314 | -0.890 | 0.0021 | Yes |
