Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CANCER_UNDIFFERENTIATED_META_UP |
| Enrichment Score (ES) | -0.7012364 |
| Normalized Enrichment Score (NES) | -2.0669432 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0025291245 |
| FWER p-Value | 0.049 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 974 | 0.147 | -0.0457 | No |
| 2 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 1840 | 0.100 | -0.0922 | No |
| 3 | ADRM1 | ADRM1 Entrez, Source | adhesion regulating molecule 1 | 1955 | 0.095 | -0.0830 | No |
| 4 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 2764 | 0.072 | -0.1303 | No |
| 5 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 4370 | 0.040 | -0.2434 | No |
| 6 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4390 | 0.040 | -0.2375 | No |
| 7 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 4411 | 0.039 | -0.2316 | No |
| 8 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4470 | 0.038 | -0.2289 | No |
| 9 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 4656 | 0.035 | -0.2362 | No |
| 10 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 5860 | 0.016 | -0.3236 | No |
| 11 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5968 | 0.015 | -0.3289 | No |
| 12 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 6017 | 0.014 | -0.3299 | No |
| 13 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 6454 | 0.007 | -0.3614 | No |
| 14 | CCT6A | CCT6A Entrez, Source | chaperonin containing TCP1, subunit 6A (zeta 1) | 6535 | 0.006 | -0.3663 | No |
| 15 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 6813 | 0.002 | -0.3866 | No |
| 16 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.4767 | No |
| 17 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 8416 | -0.022 | -0.5000 | No |
| 18 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8545 | -0.024 | -0.5052 | No |
| 19 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9129 | -0.035 | -0.5426 | No |
| 20 | CTSL | CTSL Entrez, Source | cathepsin L | 9328 | -0.038 | -0.5503 | No |
| 21 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 10020 | -0.053 | -0.5925 | No |
| 22 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 10798 | -0.072 | -0.6373 | No |
| 23 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.6427 | No |
| 24 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 11750 | -0.111 | -0.6729 | No |
| 25 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 12128 | -0.133 | -0.6764 | Yes |
| 26 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 12256 | -0.144 | -0.6591 | Yes |
| 27 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12313 | -0.149 | -0.6355 | Yes |
| 28 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 12372 | -0.155 | -0.6109 | Yes |
| 29 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12437 | -0.162 | -0.5855 | Yes |
| 30 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 12656 | -0.196 | -0.5654 | Yes |
| 31 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12815 | -0.228 | -0.5347 | Yes |
| 32 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12851 | -0.238 | -0.4929 | Yes |
| 33 | TUBB | TUBB Entrez, Source | tubulin, beta | 13001 | -0.292 | -0.4497 | Yes |
| 34 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13131 | -0.385 | -0.3877 | Yes |
| 35 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13267 | -0.614 | -0.2833 | Yes |
| 36 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13280 | -0.659 | -0.1613 | Yes |
| 37 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13314 | -0.890 | 0.0021 | Yes |
