Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | CARBON_CARBON_LYASE_ACTIVITY |
| Enrichment Score (ES) | 0.71507365 |
| Normalized Enrichment Score (NES) | 1.8776933 |
| Nominal p-value | 0.002232143 |
| FDR q-value | 0.008301893 |
| FWER p-Value | 0.576 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 54 | 0.488 | 0.2181 | Yes |
| 2 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 174 | 0.334 | 0.3610 | Yes |
| 3 | ACMSD | ACMSD Entrez, Source | aminocarboxymuconate semialdehyde decarboxylase | 208 | 0.306 | 0.4979 | Yes |
| 4 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 651 | 0.179 | 0.5463 | Yes |
| 5 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 662 | 0.178 | 0.6266 | Yes |
| 6 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 1007 | 0.144 | 0.6662 | Yes |
| 7 | HDC | HDC Entrez, Source | histidine decarboxylase | 1527 | 0.112 | 0.6782 | Yes |
| 8 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 1678 | 0.106 | 0.7151 | Yes |
| 9 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 2566 | 0.078 | 0.6839 | No |
| 10 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 3035 | 0.066 | 0.6787 | No |
| 11 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 4162 | 0.044 | 0.6140 | No |
| 12 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 5019 | 0.029 | 0.5628 | No |
| 13 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 5487 | 0.022 | 0.5377 | No |
| 14 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 5718 | 0.018 | 0.5289 | No |
| 15 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 6026 | 0.014 | 0.5121 | No |
| 16 | UROD | UROD Entrez, Source | uroporphyrinogen decarboxylase | 7789 | -0.012 | 0.3853 | No |
| 17 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 8401 | -0.021 | 0.3492 | No |
| 18 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9779 | -0.047 | 0.2674 | No |
