Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.42763993 |
| Normalized Enrichment Score (NES) | 1.5277797 |
| Nominal p-value | 0.011933174 |
| FDR q-value | 0.10523027 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 43 | 0.515 | 0.0651 | Yes |
| 2 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 140 | 0.368 | 0.1067 | Yes |
| 3 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 212 | 0.305 | 0.1418 | Yes |
| 4 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 230 | 0.293 | 0.1794 | Yes |
| 5 | MIOX | MIOX Entrez, Source | myo-inositol oxygenase | 234 | 0.291 | 0.2179 | Yes |
| 6 | ACN9 | ACN9 Entrez, Source | ACN9 homolog (S. cerevisiae) | 284 | 0.273 | 0.2504 | Yes |
| 7 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 314 | 0.263 | 0.2831 | Yes |
| 8 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 378 | 0.240 | 0.3102 | Yes |
| 9 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 412 | 0.227 | 0.3379 | Yes |
| 10 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 563 | 0.190 | 0.3519 | Yes |
| 11 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 599 | 0.186 | 0.3739 | Yes |
| 12 | PDK1 | PDK1 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 1 | 673 | 0.176 | 0.3918 | Yes |
| 13 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 800 | 0.163 | 0.4039 | Yes |
| 14 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 951 | 0.149 | 0.4124 | Yes |
| 15 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 1007 | 0.144 | 0.4273 | Yes |
| 16 | GALNT5 | GALNT5 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) | 1333 | 0.122 | 0.4191 | Yes |
| 17 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1494 | 0.114 | 0.4221 | Yes |
| 18 | NANP | NANP Entrez, Source | N-acetylneuraminic acid phosphatase | 1648 | 0.107 | 0.4247 | Yes |
| 19 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 2259 | 0.086 | 0.3902 | Yes |
| 20 | SLC35A3 | SLC35A3 Entrez, Source | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2379 | 0.083 | 0.3923 | Yes |
| 21 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 2529 | 0.079 | 0.3915 | Yes |
| 22 | EPM2A | EPM2A Entrez, Source | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 2594 | 0.077 | 0.3968 | Yes |
| 23 | NDST1 | NDST1 Entrez, Source | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 2645 | 0.075 | 0.4030 | Yes |
| 24 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 2648 | 0.075 | 0.4128 | Yes |
| 25 | CHST12 | CHST12 Entrez, Source | carbohydrate (chondroitin 4) sulfotransferase 12 | 2721 | 0.073 | 0.4171 | Yes |
| 26 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2780 | 0.072 | 0.4223 | Yes |
| 27 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 2834 | 0.071 | 0.4276 | Yes |
| 28 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3058 | 0.065 | 0.4195 | No |
| 29 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 3136 | 0.064 | 0.4221 | No |
| 30 | CHST3 | CHST3 Entrez, Source | carbohydrate (chondroitin 6) sulfotransferase 3 | 3239 | 0.061 | 0.4226 | No |
| 31 | FPGT | FPGT Entrez, Source | fucose-1-phosphate guanylyltransferase | 3810 | 0.050 | 0.3862 | No |
| 32 | LECT1 | LECT1 Entrez, Source | leukocyte cell derived chemotaxin 1 | 4046 | 0.046 | 0.3745 | No |
| 33 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 4162 | 0.044 | 0.3717 | No |
| 34 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 4892 | 0.031 | 0.3208 | No |
| 35 | ARPP-19 | ARPP-19 Entrez, Source | - | 5020 | 0.029 | 0.3151 | No |
| 36 | GALK1 | GALK1 Entrez, Source | galactokinase 1 | 5339 | 0.024 | 0.2943 | No |
| 37 | UGP2 | UGP2 Entrez, Source | UDP-glucose pyrophosphorylase 2 | 5626 | 0.020 | 0.2754 | No |
| 38 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 5718 | 0.018 | 0.2710 | No |
| 39 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 5720 | 0.018 | 0.2734 | No |
| 40 | ST3GAL6 | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 5745 | 0.018 | 0.2740 | No |
| 41 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 5789 | 0.018 | 0.2731 | No |
| 42 | IPPK | IPPK Entrez, Source | inositol 1,3,4,5,6-pentakisphosphate 2-kinase | 6008 | 0.014 | 0.2585 | No |
| 43 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 6929 | 0.001 | 0.1893 | No |
| 44 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 7124 | -0.002 | 0.1749 | No |
| 45 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 7127 | -0.002 | 0.1750 | No |
| 46 | B4GALT7 | B4GALT7 Entrez, Source | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) | 7186 | -0.003 | 0.1711 | No |
| 47 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 7269 | -0.004 | 0.1654 | No |
| 48 | GFPT2 | GFPT2 Entrez, Source | glutamine-fructose-6-phosphate transaminase 2 | 7852 | -0.013 | 0.1233 | No |
| 49 | EXTL2 | EXTL2 Entrez, Source | exostoses (multiple)-like 2 | 7923 | -0.014 | 0.1199 | No |
| 50 | PYGM | PYGM Entrez, Source | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | 8011 | -0.015 | 0.1153 | No |
| 51 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 8036 | -0.015 | 0.1156 | No |
| 52 | LALBA | LALBA Entrez, Source | lactalbumin, alpha- | 8293 | -0.020 | 0.0989 | No |
| 53 | XYLT1 | XYLT1 Entrez, Source | xylosyltransferase I | 8993 | -0.032 | 0.0505 | No |
| 54 | TREH | TREH Entrez, Source | trehalase (brush-border membrane glycoprotein) | 9359 | -0.039 | 0.0281 | No |
| 55 | NAGK | NAGK Entrez, Source | N-acetylglucosamine kinase | 9565 | -0.043 | 0.0184 | No |
| 56 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9779 | -0.047 | 0.0086 | No |
| 57 | GNS | GNS Entrez, Source | glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) | 9802 | -0.048 | 0.0133 | No |
| 58 | GMDS | GMDS Entrez, Source | GDP-mannose 4,6-dehydratase | 9847 | -0.049 | 0.0164 | No |
| 59 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 10756 | -0.071 | -0.0425 | No |
| 60 | GFPT1 | GFPT1 Entrez, Source | glutamine-fructose-6-phosphate transaminase 1 | 10795 | -0.072 | -0.0357 | No |
| 61 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 10797 | -0.072 | -0.0262 | No |
| 62 | CHST1 | CHST1 Entrez, Source | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 10942 | -0.077 | -0.0269 | No |
| 63 | CHIA | CHIA Entrez, Source | chitinase, acidic | 10976 | -0.078 | -0.0190 | No |
| 64 | GAA | GAA Entrez, Source | glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) | 11007 | -0.079 | -0.0108 | No |
| 65 | GUSB | GUSB Entrez, Source | glucuronidase, beta | 11065 | -0.081 | -0.0044 | No |
| 66 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11474 | -0.098 | -0.0221 | No |
| 67 | HPSE | HPSE Entrez, Source | heparanase | 11761 | -0.112 | -0.0288 | No |
| 68 | IL17F | IL17F Entrez, Source | interleukin 17F | 11826 | -0.115 | -0.0184 | No |
| 69 | HK1 | HK1 Entrez, Source | hexokinase 1 | 12060 | -0.129 | -0.0188 | No |
| 70 | PYGB | PYGB Entrez, Source | phosphorylase, glycogen; brain | 12718 | -0.208 | -0.0407 | No |
| 71 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 12804 | -0.226 | -0.0171 | No |
| 72 | ST3GAL2 | ST3GAL2 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | 13177 | -0.434 | 0.0124 | No |
