Details for gene set CELLULAR_LIPID_METABOLIC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos
Phenotype	class.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in class	double_gel_72h
GeneSet	CELLULAR_LIPID_METABOLIC_PROCESS
Enrichment Score (ES)	0.41687414
Normalized Enrichment Score (NES)	1.6985707
Nominal p-value	0.002967359
FDR q-value	0.03647462
FWER p-Value	0.999

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PEMT	PEMT Entrez, Source	phosphatidylethanolamine N-methyltransferase	8	0.798	0.0412	Yes
2	SLC27A5	SLC27A5 Entrez, Source	solute carrier family 27 (fatty acid transporter), member 5	9	0.779	0.0821	Yes
3	GLYAT	GLYAT Entrez, Source	glycine-N-acyltransferase	33	0.554	0.1094	Yes
4	HACL1	HACL1 Entrez, Source	2-hydroxyacyl-CoA lyase 1	54	0.488	0.1335	Yes
5	ACOX2	ACOX2 Entrez, Source	acyl-Coenzyme A oxidase 2, branched chain	95	0.419	0.1524	Yes
6	NR0B2	NR0B2 Entrez, Source	nuclear receptor subfamily 0, group B, member 2	104	0.416	0.1736	Yes
7	APOM	APOM Entrez, Source	apolipoprotein M	113	0.401	0.1940	Yes
8	IDI1	IDI1 Entrez, Source	isopentenyl-diphosphate delta isomerase 1	136	0.372	0.2119	Yes
9	LCAT	LCAT Entrez, Source	lecithin-cholesterol acyltransferase	142	0.365	0.2306	Yes
10	FADS2	FADS2 Entrez, Source	fatty acid desaturase 2	182	0.324	0.2447	Yes
11	NR1H4	NR1H4 Entrez, Source	nuclear receptor subfamily 1, group H, member 4	246	0.288	0.2550	Yes
12	SC4MOL	SC4MOL Entrez, Source	sterol-C4-methyl oxidase-like	444	0.218	0.2515	Yes
13	FDPS	FDPS Entrez, Source	farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)	462	0.212	0.2613	Yes
14	ACADVL	ACADVL Entrez, Source	acyl-Coenzyme A dehydrogenase, very long chain	482	0.207	0.2707	Yes
15	DGAT2	DGAT2 Entrez, Source	diacylglycerol O-acyltransferase homolog 2 (mouse)	503	0.201	0.2798	Yes
16	HAO2	HAO2 Entrez, Source	hydroxyacid oxidase 2 (long chain)	536	0.195	0.2875	Yes
17	FAAH	FAAH Entrez, Source	fatty acid amide hydrolase	553	0.192	0.2964	Yes
18	MVK	MVK Entrez, Source	mevalonate kinase (mevalonic aciduria)	578	0.188	0.3044	Yes
19	BAAT	BAAT Entrez, Source	bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)	597	0.186	0.3128	Yes
20	ALDH5A1	ALDH5A1 Entrez, Source	aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)	612	0.184	0.3215	Yes
21	ACOT12	ACOT12 Entrez, Source	acyl-CoA thioesterase 12	619	0.184	0.3306	Yes
22	ECHS1	ECHS1 Entrez, Source	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	633	0.182	0.3392	Yes
23	DHCR24	DHCR24 Entrez, Source	24-dehydrocholesterol reductase	685	0.175	0.3445	Yes
24	DHCR7	DHCR7 Entrez, Source	7-dehydrocholesterol reductase	693	0.174	0.3531	Yes
25	PCYT2	PCYT2 Entrez, Source	phosphate cytidylyltransferase 2, ethanolamine	748	0.168	0.3578	Yes
26	CHPT1	CHPT1 Entrez, Source	choline phosphotransferase 1	778	0.165	0.3642	Yes
27	NR1I2	NR1I2 Entrez, Source	nuclear receptor subfamily 1, group I, member 2	855	0.157	0.3667	Yes
28	CYP4F2	CYP4F2 Entrez, Source	cytochrome P450, family 4, subfamily F, polypeptide 2	933	0.150	0.3687	Yes
29	AKR1B10	AKR1B10 Entrez, Source	aldo-keto reductase family 1, member B10 (aldose reductase)	1044	0.141	0.3678	Yes
30	CPT1A	CPT1A Entrez, Source	carnitine palmitoyltransferase 1A (liver)	1046	0.140	0.3751	Yes
31	PECI	PECI Entrez, Source	peroxisomal D3,D2-enoyl-CoA isomerase	1151	0.133	0.3742	Yes
32	ST8SIA1	ST8SIA1 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	1223	0.128	0.3755	Yes
33	SMPD3	SMPD3 Entrez, Source	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	1232	0.128	0.3816	Yes
34	PPARA	PPARA Entrez, Source	peroxisome proliferative activated receptor, alpha	1252	0.127	0.3868	Yes
35	PI4K2A			1329	0.123	0.3875	Yes
36	NSDHL	NSDHL Entrez, Source	NAD(P) dependent steroid dehydrogenase-like	1370	0.121	0.3907	Yes
37	PPARD	PPARD Entrez, Source	peroxisome proliferative activated receptor, delta	1387	0.119	0.3958	Yes
38	ACADSB	ACADSB Entrez, Source	acyl-Coenzyme A dehydrogenase, short/branched chain	1480	0.114	0.3948	Yes
39	FADS1	FADS1 Entrez, Source	fatty acid desaturase 1	1495	0.114	0.3997	Yes
40	RARRES2	RARRES2 Entrez, Source	retinoic acid receptor responder (tazarotene induced) 2	1501	0.113	0.4052	Yes
41	CD74	CD74 Entrez, Source	CD74 molecule, major histocompatibility complex, class II invariant chain	1524	0.112	0.4094	Yes
42	SCP2	SCP2 Entrez, Source	sterol carrier protein 2	1632	0.107	0.4070	Yes
43	MLYCD	MLYCD Entrez, Source	malonyl-CoA decarboxylase	1678	0.106	0.4091	Yes
44	PLA2G2D	PLA2G2D Entrez, Source	phospholipase A2, group IID	1734	0.104	0.4104	Yes
45	B4GALNT1	B4GALNT1 Entrez, Source	beta-1,4-N-acetyl-galactosaminyl transferase 1	1769	0.102	0.4131	Yes
46	AKR1D1	AKR1D1 Entrez, Source	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	1859	0.099	0.4116	Yes
47	BMP6	BMP6 Entrez, Source	bone morphogenetic protein 6	1877	0.098	0.4155	Yes
48	ABCD2	ABCD2 Entrez, Source	ATP-binding cassette, sub-family D (ALD), member 2	1926	0.096	0.4169	Yes
49	RDH11	RDH11 Entrez, Source	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	2069	0.092	0.4109	No
50	APOC3	APOC3 Entrez, Source	apolipoprotein C-III	2176	0.089	0.4075	No
51	DHRS3	DHRS3 Entrez, Source	dehydrogenase/reductase (SDR family) member 3	2353	0.084	0.3986	No
52	CPT1B	CPT1B Entrez, Source	carnitine palmitoyltransferase 1B (muscle)	2496	0.080	0.3920	No
53	ADIPOR2	ADIPOR2 Entrez, Source	adiponectin receptor 2	2598	0.076	0.3884	No
54	PLA2G6	PLA2G6 Entrez, Source	phospholipase A2, group VI (cytosolic, calcium-independent)	2615	0.076	0.3911	No
55	ST6GALNAC6	ST6GALNAC6 Entrez, Source	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	2672	0.074	0.3908	No
56	PLCB2	PLCB2 Entrez, Source	phospholipase C, beta 2	2782	0.072	0.3863	No
57	PEX7	PEX7 Entrez, Source	peroxisomal biogenesis factor 7	3029	0.066	0.3711	No
58	ACOX3	ACOX3 Entrez, Source	acyl-Coenzyme A oxidase 3, pristanoyl	3046	0.066	0.3733	No
59	TNFRSF1A	TNFRSF1A Entrez, Source	tumor necrosis factor receptor superfamily, member 1A	3063	0.065	0.3755	No
60	PLA2G5	PLA2G5 Entrez, Source	phospholipase A2, group V	3301	0.060	0.3607	No
61	GNPAT	GNPAT Entrez, Source	glyceronephosphate O-acyltransferase	3398	0.058	0.3564	No
62	ST8SIA5	ST8SIA5 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	3625	0.053	0.3421	No
63	ACOT2	ACOT2 Entrez, Source	acyl-CoA thioesterase 2	3642	0.053	0.3437	No
64	PIGK	PIGK Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class K	3814	0.050	0.3333	No
65	AGPAT1	AGPAT1 Entrez, Source	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	4028	0.046	0.3195	No
66	APOA1	APOA1 Entrez, Source	apolipoprotein A-I	4169	0.043	0.3112	No
67	HDLBP	HDLBP Entrez, Source	high density lipoprotein binding protein (vigilin)	4270	0.042	0.3058	No
68	ACADM	ACADM Entrez, Source	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	4299	0.041	0.3059	No
69	BRCA1	BRCA1 Entrez, Source	breast cancer 1, early onset	4326	0.041	0.3060	No
70	PIGC	PIGC Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class C	4338	0.040	0.3073	No
71	HSD11B2	HSD11B2 Entrez, Source	hydroxysteroid (11-beta) dehydrogenase 2	4542	0.037	0.2939	No
72	HADHB	HADHB Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	4675	0.035	0.2857	No
73	PIK3R1	PIK3R1 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)	4760	0.033	0.2810	No
74	HPGD	HPGD Entrez, Source	hydroxyprostaglandin dehydrogenase 15-(NAD)	4803	0.032	0.2796	No
75	DHRS9	DHRS9 Entrez, Source	dehydrogenase/reductase (SDR family) member 9	4865	0.031	0.2766	No
76	PTGS1	PTGS1 Entrez, Source	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	4887	0.031	0.2766	No
77	CLN8	CLN8 Entrez, Source	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	4936	0.030	0.2746	No
78	HSD3B1	HSD3B1 Entrez, Source	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	4997	0.029	0.2715	No
79	DGAT1	DGAT1 Entrez, Source	diacylglycerol O-acyltransferase homolog 1 (mouse)	5118	0.027	0.2639	No
80	CLN3	CLN3 Entrez, Source	ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	5208	0.026	0.2585	No
81	GPX4	GPX4 Entrez, Source	glutathione peroxidase 4 (phospholipid hydroperoxidase)	5373	0.024	0.2473	No
82	CNBP	CNBP Entrez, Source	CCHC-type zinc finger, nucleic acid binding protein	5438	0.023	0.2436	No
83	MBTPS2	MBTPS2 Entrez, Source	membrane-bound transcription factor peptidase, site 2	5566	0.021	0.2351	No
84	PTGES	PTGES Entrez, Source	prostaglandin E synthase	5602	0.020	0.2335	No
85	PTEN	PTEN Entrez, Source	phosphatase and tensin homolog (mutated in multiple advanced cancers 1)	5720	0.018	0.2256	No
86	ST3GAL6	ST3GAL6 Entrez, Source	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	5745	0.018	0.2247	No
87	APOA5	APOA5 Entrez, Source	apolipoprotein A-V	5815	0.017	0.2204	No
88	ECH1	ECH1 Entrez, Source	enoyl Coenzyme A hydratase 1, peroxisomal	5859	0.016	0.2180	No
89	ACADS	ACADS Entrez, Source	acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain	5886	0.016	0.2169	No
90	AGPS	AGPS Entrez, Source	alkylglycerone phosphate synthase	6079	0.013	0.2030	No
91	SPTLC1	SPTLC1 Entrez, Source	serine palmitoyltransferase, long chain base subunit 1	6112	0.013	0.2012	No
92	PCYT1B	PCYT1B Entrez, Source	phosphate cytidylyltransferase 1, choline, beta	6186	0.012	0.1963	No
93	FDXR	FDXR Entrez, Source	ferredoxin reductase	6391	0.008	0.1812	No
94	ST8SIA3	ST8SIA3 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	6457	0.007	0.1767	No
95	IL4	IL4 Entrez, Source	interleukin 4	6466	0.007	0.1764	No
96	CYP19A1	CYP19A1 Entrez, Source	cytochrome P450, family 19, subfamily A, polypeptide 1	6596	0.005	0.1669	No
97	PTGDS	PTGDS Entrez, Source	prostaglandin D2 synthase 21kDa (brain)	6738	0.003	0.1564	No
98	PRDX6	PRDX6 Entrez, Source	peroxiredoxin 6	6768	0.003	0.1544	No
99	ST6GALNAC4	ST6GALNAC4 Entrez, Source	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	6968	0.000	0.1393	No
100	IHPK2	IHPK2 Entrez, Source	inositol hexaphosphate kinase 2	7190	-0.003	0.1227	No
101	GBA2	GBA2 Entrez, Source	glucosidase, beta (bile acid) 2	7269	-0.004	0.1170	No
102	NEU3	NEU3 Entrez, Source	sialidase 3 (membrane sialidase)	7444	-0.007	0.1042	No
103	PLAA	PLAA Entrez, Source	phospholipase A2-activating protein	7627	-0.009	0.0909	No
104	SERINC1	SERINC1 Entrez, Source	serine incorporator 1	7788	-0.012	0.0793	No
105	SOD1	SOD1 Entrez, Source	superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))	7883	-0.013	0.0729	No
106	PIGV	PIGV Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class V	7912	-0.014	0.0715	No
107	PPARGC1A	PPARGC1A Entrez, Source	peroxisome proliferative activated receptor, gamma, coactivator 1, alpha	8036	-0.015	0.0630	No
108	RETSAT	RETSAT Entrez, Source	retinol saturase (all-trans-retinol 13,14-reductase)	8072	-0.016	0.0612	No
109	HSD3B7	HSD3B7 Entrez, Source	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	8089	-0.016	0.0608	No
110	SULT2A1	SULT2A1 Entrez, Source	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	8105	-0.016	0.0605	No
111	PPAP2A	PPAP2A Entrez, Source	phosphatidic acid phosphatase type 2A	8226	-0.018	0.0524	No
112	ADIPOR1	ADIPOR1 Entrez, Source	adiponectin receptor 1	8460	-0.022	0.0359	No
113	DPM2	DPM2 Entrez, Source	dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit	8478	-0.023	0.0358	No
114	STUB1	STUB1 Entrez, Source	STIP1 homology and U-box containing protein 1	8548	-0.024	0.0318	No
115	CYP7B1	CYP7B1 Entrez, Source	cytochrome P450, family 7, subfamily B, polypeptide 1	9114	-0.034	-0.0092	No
116	PIGS	PIGS Entrez, Source	phosphatidylinositol glycan anchor biosynthesis, class S	9263	-0.037	-0.0185	No
117	MIF	MIF Entrez, Source	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	9316	-0.038	-0.0205	No
118	PPT1	PPT1 Entrez, Source	palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)	9419	-0.040	-0.0261	No
119	ASAH2	ASAH2 Entrez, Source	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2	9653	-0.045	-0.0414	No
120	SMPD2	SMPD2 Entrez, Source	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	9756	-0.047	-0.0467	No
121	NR0B1	NR0B1 Entrez, Source	nuclear receptor subfamily 0, group B, member 1	9783	-0.047	-0.0462	No
122	IMPA1	IMPA1 Entrez, Source	inositol(myo)-1(or 4)-monophosphatase 1	9804	-0.048	-0.0452	No
123	PSAP	PSAP Entrez, Source	prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)	9922	-0.051	-0.0514	No
124	B4GALT4	B4GALT4 Entrez, Source	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	9970	-0.052	-0.0523	No
125	PLCD1	PLCD1 Entrez, Source	phospholipase C, delta 1	10095	-0.054	-0.0588	No
126	CYP11A1	CYP11A1 Entrez, Source	cytochrome P450, family 11, subfamily A, polypeptide 1	10102	-0.054	-0.0564	No
127	LTA4H	LTA4H Entrez, Source	leukotriene A4 hydrolase	10430	-0.062	-0.0780	No
128	PNLIPRP2	PNLIPRP2 Entrez, Source	pancreatic lipase-related protein 2	10564	-0.066	-0.0846	No
129	CEL	CEL Entrez, Source	carboxyl ester lipase (bile salt-stimulated lipase)	10808	-0.073	-0.0992	No
130	LPL	LPL Entrez, Source	lipoprotein lipase	10988	-0.078	-0.1087	No
131	YWHAH	YWHAH Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	10999	-0.079	-0.1053	No
132	TSPO	TSPO Entrez, Source	translocator protein (18kDa)	11004	-0.079	-0.1015	No
133	CD81	CD81 Entrez, Source	CD81 molecule	11022	-0.079	-0.0986	No
134	IHPK1	IHPK1 Entrez, Source	inositol hexaphosphate kinase 1	11145	-0.083	-0.1035	No
135	PIP5K1A	PIP5K1A Entrez, Source	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	11170	-0.084	-0.1009	No
136	STS	STS Entrez, Source	steroid sulfatase (microsomal), arylsulfatase C, isozyme S	11277	-0.089	-0.1042	No
137	DEGS1	DEGS1 Entrez, Source	degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)	11324	-0.092	-0.1029	No
138	SCARB1	SCARB1 Entrez, Source	scavenger receptor class B, member 1	11498	-0.099	-0.1108	No
139	SHH	SHH Entrez, Source	sonic hedgehog homolog (Drosophila)	11581	-0.103	-0.1116	No
140	CROT	CROT Entrez, Source	carnitine O-octanoyltransferase	11691	-0.109	-0.1142	No
141	NPC2	NPC2 Entrez, Source	Niemann-Pick disease, type C2	12096	-0.131	-0.1380	No
142	AGPAT6	AGPAT6 Entrez, Source	1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)	12308	-0.149	-0.1461	No
143	ASAH1	ASAH1 Entrez, Source	N-acylsphingosine amidohydrolase (acid ceramidase) 1	12353	-0.153	-0.1414	No
144	SGPL1	SGPL1 Entrez, Source	sphingosine-1-phosphate lyase 1	12434	-0.162	-0.1390	No
145	SPHK1	SPHK1 Entrez, Source	sphingosine kinase 1	12507	-0.172	-0.1355	No
146	PLA1A	PLA1A Entrez, Source	phospholipase A1 member A	12708	-0.206	-0.1398	No
147	UGCG	UGCG Entrez, Source	UDP-glucose ceramide glucosyltransferase	12906	-0.254	-0.1414	No
148	LYPLA3	LYPLA3 Entrez, Source	lysophospholipase 3 (lysosomal phospholipase A2)	12939	-0.266	-0.1299	No
149	PLCE1	PLCE1 Entrez, Source	phospholipase C, epsilon 1	13110	-0.363	-0.1237	No
150	ABCG1	ABCG1 Entrez, Source	ATP-binding cassette, sub-family G (WHITE), member 1	13162	-0.417	-0.1057	No
151	SERINC5	SERINC5 Entrez, Source	serine incorporator 5	13225	-0.503	-0.0840	No
152	SERINC2	SERINC2 Entrez, Source	serine incorporator 2	13234	-0.520	-0.0574	No
153	SOAT1	SOAT1 Entrez, Source	sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1	13248	-0.551	-0.0295	No
154	ADM	ADM Entrez, Source	adrenomedullin	13287	-0.697	0.0042	No