Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classsingle_gel_72h
GeneSetCELL_CYCLE_GO_0007049
Enrichment Score (ES)-0.45674753
Normalized Enrichment Score (NES)-1.7161803
Nominal p-value0.0
FDR q-value0.057786725
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: CELL_CYCLE_GO_0007049   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MDM4MDM4
Entrez,  Source
Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)1410.3660.0132No
2CDK5R1CDK5R1
Entrez,  Source
cyclin-dependent kinase 5, regulatory subunit 1 (p35)4550.2140.0035No
3TGFATGFA
Entrez,  Source
transforming growth factor, alpha9860.146-0.0271No
4CENTD2CENTD2
Entrez,  Source
centaurin, delta 211370.135-0.0297No
5INHAINHA
Entrez,  Source
inhibin, alpha12700.126-0.0315No
6NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 112770.125-0.0237No
7CDK5RAP3CDK5RAP3
Entrez,  Source
CDK5 regulatory subunit associated protein 312780.125-0.0155No
8KATNA1KATNA1
Entrez,  Source
katanin p60 (ATPase-containing) subunit A 113450.122-0.0126No
9MAD2L2MAD2L2
Entrez,  Source
MAD2 mitotic arrest deficient-like 2 (yeast)13550.121-0.0053No
10GAS7GAS7
Entrez,  Source
growth arrest-specific 714420.116-0.0042No
11BMP4BMP4
Entrez,  Source
bone morphogenetic protein 415260.112-0.0032No
12MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)16090.108-0.0023No
13SUGT1SUGT1
Entrez,  Source
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)16810.106-0.0008No
14EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)17480.1030.0009No
15TBRG4TBRG4
Entrez,  Source
transforming growth factor beta regulator 420190.093-0.0134No
16PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa22350.087-0.0241No
17RUNX3RUNX3
Entrez,  Source
runt-related transcription factor 324260.082-0.0331No
18GTPBP4GTPBP4
Entrez,  Source
GTP binding protein 424840.080-0.0322No
19CDC25ACDC25A
Entrez,  Source
cell division cycle 25A25270.079-0.0302No
20SPDYASPDYA
Entrez,  Source
speedy homolog A (Drosophila)25360.079-0.0257No
21BMP7BMP7
Entrez,  Source
bone morphogenetic protein 7 (osteogenic protein 1)26690.074-0.0309No
22CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 627460.073-0.0319No
23RB1RB1
Entrez,  Source
retinoblastoma 1 (including osteosarcoma)27650.072-0.0285No
24RHOBRHOB
Entrez,  Source
ras homolog gene family, member B28000.071-0.0264No
25EGFL6EGFL6
Entrez,  Source
EGF-like-domain, multiple 628300.071-0.0240No
26DUSP13DUSP13
Entrez,  Source
dual specificity phosphatase 1329970.067-0.0322No
27RAD17RAD17
Entrez,  Source
RAD17 homolog (S. pombe)36070.054-0.0749No
28SMC1ASMC1A
Entrez,  Source
structural maintenance of chromosomes 1A37440.051-0.0819No
29NOTCH2NOTCH2
Entrez,  Source
Notch homolog 2 (Drosophila)39890.047-0.0974No
30ASNSASNS
Entrez,  Source
asparagine synthetase42450.042-0.1139No
31CDKN3CDKN3
Entrez,  Source
cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)43900.040-0.1223No
32PPP6CPPP6C
Entrez,  Source
protein phosphatase 6, catalytic subunit47150.034-0.1446No
33HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)48030.032-0.1491No
34TARDBPTARDBP
Entrez,  Source
TAR DNA binding protein53320.024-0.1876No
35NASPNASP
Entrez,  Source
nuclear autoantigenic sperm protein (histone-binding)55970.020-0.2063No
36PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C56080.020-0.2057No
37PPM1GPPM1G
Entrez,  Source
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform56960.019-0.2111No
38PPP5CPPP5C
Entrez,  Source
protein phosphatase 5, catalytic subunit57030.019-0.2103No
39PTENPTEN
Entrez,  Source
phosphatase and tensin homolog (mutated in multiple advanced cancers 1)57200.018-0.2103No
40LIG3LIG3
Entrez,  Source
ligase III, DNA, ATP-dependent58650.016-0.2202No
41BRCA2BRCA2
Entrez,  Source
breast cancer 2, early onset59240.015-0.2236No
42TTNTTN
Entrez,  Source
titin59940.014-0.2279No
43APBB1APBB1
Entrez,  Source
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)60000.014-0.2273No
44CDK5RAP1CDK5RAP1
Entrez,  Source
CDK5 regulatory subunit associated protein 160270.014-0.2284No
45AKAP8AKAP8
Entrez,  Source
A kinase (PRKA) anchor protein 861510.012-0.2369No
46TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)61580.012-0.2366No
47CDC16CDC16
Entrez,  Source
CDC16 cell division cycle 16 homolog (S. cerevisiae)61640.012-0.2362No
48MRE11AMRE11A
Entrez,  Source
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)62210.011-0.2397No
49TBX3TBX3
Entrez,  Source
T-box 3 (ulnar mammary syndrome)64760.007-0.2586No
50GSPT1GSPT1
Entrez,  Source
G1 to S phase transition 167170.004-0.2765No
51CDKN2ACDKN2A
Entrez,  Source
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)67550.003-0.2791No
52NEK6NEK6
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 667780.003-0.2806No
53CDK10CDK10
Entrez,  Source
cyclin-dependent kinase (CDC2-like) 1067960.003-0.2817No
54NPM2NPM2
Entrez,  Source
nucleophosmin/nucleoplasmin, 268280.002-0.2839No
55CHFRCHFR
Entrez,  Source
checkpoint with forkhead and ring finger domains68930.001-0.2887No
56DLG1DLG1
Entrez,  Source
discs, large homolog 1 (Drosophila)69580.000-0.2935No
57INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)6984-0.000-0.2954No
58NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)7074-0.001-0.3021No
59AIF1AIF1
Entrez,  Source
allograft inflammatory factor 17500-0.007-0.3338No
60CDC2L5CDC2L5
Entrez,  Source
cell division cycle 2-like 5 (cholinesterase-related cell division controller)7727-0.011-0.3503No
61CUL5CUL5
Entrez,  Source
cullin 57748-0.011-0.3511No
62CD28CD28
Entrez,  Source
CD28 molecule7763-0.011-0.3514No
63SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase7785-0.012-0.3522No
64ACVR1ACVR1
Entrez,  Source
activin A receptor, type I7793-0.012-0.3519No
65GPS1GPS1
Entrez,  Source
G protein pathway suppressor 17796-0.012-0.3513No
66CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 28216-0.018-0.3819No
67UHMK1UHMK1
Entrez,  Source
U2AF homology motif (UHM) kinase 18307-0.020-0.3874No
68CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)8319-0.020-0.3869No
69CCNA1CCNA1
Entrez,  Source
cyclin A18384-0.021-0.3904No
70KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)8416-0.022-0.3913No
71CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)8462-0.022-0.3933No
72RASSF1RASSF1
Entrez,  Source
Ras association (RalGDS/AF-6) domain family 18495-0.023-0.3942No
73NBNNBN
Entrez,  Source
nibrin8726-0.027-0.4099No
74PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)8736-0.027-0.4088No
75CETN3CETN3
Entrez,  Source
centrin, EF-hand protein, 3 (CDC31 homolog, yeast)8746-0.027-0.4077No
76UBBUBB
Entrez,  Source
ubiquitin B8839-0.029-0.4128No
77EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 28954-0.031-0.4194No
78MFN2MFN2
Entrez,  Source
mitofusin 29004-0.032-0.4210No
79MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 119043-0.033-0.4217No
80RANRAN
Entrez,  Source
RAN, member RAS oncogene family9203-0.036-0.4315No
81PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa9229-0.036-0.4310No
82MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 69252-0.037-0.4302No
83ZW10ZW10
Entrez,  Source
ZW10, kinetochore associated, homolog (Drosophila)9270-0.037-0.4291No
84CDKN2CCDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)9276-0.037-0.4270No
85EREGEREG
Entrez,  Source
epiregulin9343-0.039-0.4295No
86TUBG1TUBG1
Entrez,  Source
tubulin, gamma 19358-0.039-0.4280No
87SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)9459-0.041-0.4330No
88ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)9513-0.042-0.4342No
89DDB1DDB1
Entrez,  Source
damage-specific DNA binding protein 1, 127kDa9544-0.042-0.4337No
90MADDMADD
Entrez,  Source
MAP-kinase activating death domain9699-0.046-0.4424No
91SYCP1SYCP1
Entrez,  Source
synaptonemal complex protein 19738-0.046-0.4423No
92PPP1R9BPPP1R9B
Entrez,  Source
protein phosphatase 1, regulatory subunit 9B, spinophilin9743-0.047-0.4395No
93APCAPC
Entrez,  Source
adenomatosis polyposis coli9845-0.049-0.4440No
94CCND3CCND3
Entrez,  Source
cyclin D39869-0.049-0.4425No
95POLD1POLD1
Entrez,  Source
polymerase (DNA directed), delta 1, catalytic subunit 125kDa9909-0.050-0.4422No
96GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha9946-0.051-0.4416No
97CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)10008-0.052-0.4428No
98CETN1CETN1
Entrez,  Source
centrin, EF-hand protein, 110032-0.053-0.4411No
99GFI1GFI1
Entrez,  Source
growth factor independent 110061-0.053-0.4397No
100HSPA2HSPA2
Entrez,  Source
heat shock 70kDa protein 210104-0.054-0.4394No
101PCAFPCAF
Entrez,  Source
p300/CBP-associated factor10191-0.056-0.4422No
102ZBTB17ZBTB17
Entrez,  Source
zinc finger and BTB domain containing 1710241-0.058-0.4421No
103SC65SC65
Entrez,  Source
-10286-0.059-0.4416No
104DCTN2DCTN2
Entrez,  Source
dynactin 2 (p50)10348-0.060-0.4423No
105ANAPC4ANAPC4
Entrez,  Source
anaphase promoting complex subunit 410467-0.063-0.4471No
106CDC23CDC23
Entrez,  Source
CDC23 (cell division cycle 23, yeast, homolog)10523-0.065-0.4471No
107STAG3STAG3
Entrez,  Source
stromal antigen 310647-0.068-0.4519Yes
108SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310686-0.069-0.4503Yes
109RAD50RAD50
Entrez,  Source
RAD50 homolog (S. cerevisiae)10695-0.070-0.4463Yes
110CDKN2BCDKN2B
Entrez,  Source
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)10726-0.071-0.4440Yes
111TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)10788-0.072-0.4439Yes
112BTG4BTG4
Entrez,  Source
B-cell translocation gene 410905-0.075-0.4477Yes
113CDKN2DCDKN2D
Entrez,  Source
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)10949-0.077-0.4460Yes
114TBRG1TBRG1
Entrez,  Source
transforming growth factor beta regulator 111092-0.082-0.4514Yes
115CCNG1CCNG1
Entrez,  Source
cyclin G111138-0.083-0.4494Yes
116USH1CUSH1C
Entrez,  Source
Usher syndrome 1C (autosomal recessive, severe)11196-0.086-0.4481Yes
117ZWINTZWINT
Entrez,  Source
ZW10 interactor11263-0.089-0.4473Yes
118STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311294-0.090-0.4437Yes
119SERTAD1SERTAD1
Entrez,  Source
SERTA domain containing 111307-0.091-0.4387Yes
120BTG3BTG3
Entrez,  Source
BTG family, member 311377-0.094-0.4377Yes
121AHRAHR
Entrez,  Source
aryl hydrocarbon receptor11463-0.098-0.4378Yes
122KHDRBS1KHDRBS1
Entrez,  Source
KH domain containing, RNA binding, signal transduction associated 111520-0.100-0.4355Yes
123MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)11555-0.102-0.4314Yes
124PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 111562-0.102-0.4251Yes
125CKAP5CKAP5
Entrez,  Source
cytoskeleton associated protein 511647-0.106-0.4245Yes
126NUMA1NUMA1
Entrez,  Source
nuclear mitotic apparatus protein 111712-0.110-0.4222Yes
127CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)11752-0.111-0.4179Yes
128ING4ING4
Entrez,  Source
inhibitor of growth family, member 411779-0.113-0.4125Yes
129ANAPC2ANAPC2
Entrez,  Source
anaphase promoting complex subunit 211844-0.116-0.4097Yes
130CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)11886-0.118-0.4051Yes
131CDC27CDC27
Entrez,  Source
cell division cycle 2711905-0.119-0.3987Yes
132AURKAAURKA
Entrez,  Source
aurora kinase A11917-0.119-0.3918Yes
133NDE1NDE1
Entrez,  Source
nudE nuclear distribution gene E homolog 1 (A. nidulans)12075-0.130-0.3952Yes
134TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 212112-0.132-0.3893Yes
135CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)12256-0.144-0.3907Yes
136CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 412272-0.146-0.3823Yes
137MAPK12MAPK12
Entrez,  Source
mitogen-activated protein kinase 1212330-0.151-0.3768Yes
138E2F1E2F1
Entrez,  Source
E2F transcription factor 112376-0.156-0.3700Yes
139CDC25BCDC25B
Entrez,  Source
cell division cycle 25B12377-0.156-0.3598Yes
140CDC37CDC37
Entrez,  Source
CDC37 cell division cycle 37 homolog (S. cerevisiae)12406-0.158-0.3516Yes
141CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)12445-0.163-0.3438Yes
142SPHK1SPHK1
Entrez,  Source
sphingosine kinase 112507-0.172-0.3372Yes
143BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)12656-0.196-0.3356Yes
144SH3BP4SH3BP4
Entrez,  Source
SH3-domain binding protein 412682-0.201-0.3244Yes
145CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)12725-0.209-0.3139Yes
146BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)12774-0.218-0.3033Yes
147BMP2BMP2
Entrez,  Source
bone morphogenetic protein 212792-0.222-0.2900Yes
148KIF2CKIF2C
Entrez,  Source
kinesin family member 2C12815-0.228-0.2768Yes
149TIMELESSTIMELESS
Entrez,  Source
timeless homolog (Drosophila)12940-0.266-0.2688Yes
150MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle12969-0.279-0.2526Yes
151KIF22KIF22
Entrez,  Source
kinesin family member 2212985-0.285-0.2352Yes
152SMC4SMC4
Entrez,  Source
structural maintenance of chromosomes 413078-0.337-0.2201Yes
153CCND2CCND2
Entrez,  Source
cyclin D213080-0.340-0.1979Yes
154CCND1CCND1
Entrez,  Source
cyclin D113085-0.343-0.1758Yes
155PAMPAM
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase13160-0.412-0.1544Yes
156BCAT1BCAT1
Entrez,  Source
branched chain aminotransferase 1, cytosolic13181-0.442-0.1271Yes
157CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 213211-0.481-0.0978Yes
158STMN1STMN1
Entrez,  Source
stathmin 1/oncoprotein 1813302-0.755-0.0552Yes
159CCNA2CCNA2
Entrez,  Source
cyclin A213314-0.8900.0021Yes
Table: GSEA details [plain text format]



Fig 2: CELL_CYCLE_GO_0007049   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CELL_CYCLE_GO_0007049: Random ES distribution   
Gene set null distribution of ES for CELL_CYCLE_GO_0007049