Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CELL_MOTILITY |
| Enrichment Score (ES) | -0.5501878 |
| Normalized Enrichment Score (NES) | -1.8241385 |
| Nominal p-value | 0.0016025641 |
| FDR q-value | 0.032188434 |
| FWER p-Value | 0.899 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 143 | 0.363 | 0.0242 | No |
| 2 | CD97 | CD97 Entrez, Source | CD97 molecule | 554 | 0.192 | 0.0119 | No |
| 3 | YARS | YARS Entrez, Source | tyrosyl-tRNA synthetase | 984 | 0.146 | -0.0064 | No |
| 4 | PALM | PALM Entrez, Source | paralemmin | 1230 | 0.128 | -0.0125 | No |
| 5 | AKAP3 | AKAP3 Entrez, Source | A kinase (PRKA) anchor protein 3 | 1334 | 0.122 | -0.0084 | No |
| 6 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 1471 | 0.115 | -0.0076 | No |
| 7 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 1781 | 0.102 | -0.0211 | No |
| 8 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 1814 | 0.101 | -0.0138 | No |
| 9 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 2004 | 0.094 | -0.0190 | No |
| 10 | HGFAC | HGFAC Entrez, Source | HGF activator | 2074 | 0.092 | -0.0153 | No |
| 11 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 2125 | 0.090 | -0.0104 | No |
| 12 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 2545 | 0.078 | -0.0344 | No |
| 13 | VNN1 | VNN1 Entrez, Source | vanin 1 | 2659 | 0.075 | -0.0357 | No |
| 14 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 2783 | 0.072 | -0.0380 | No |
| 15 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 3186 | 0.063 | -0.0623 | No |
| 16 | AKAP4 | AKAP4 Entrez, Source | A kinase (PRKA) anchor protein 4 | 3280 | 0.061 | -0.0635 | No |
| 17 | NTN1 | NTN1 Entrez, Source | netrin 1 | 3284 | 0.060 | -0.0579 | No |
| 18 | BLR1 | BLR1 Entrez, Source | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | 3382 | 0.058 | -0.0595 | No |
| 19 | IFNG | IFNG Entrez, Source | interferon, gamma | 4058 | 0.045 | -0.1060 | No |
| 20 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4604 | 0.036 | -0.1437 | No |
| 21 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 4784 | 0.033 | -0.1540 | No |
| 22 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 4923 | 0.030 | -0.1614 | No |
| 23 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 4951 | 0.030 | -0.1606 | No |
| 24 | MKLN1 | MKLN1 Entrez, Source | muskelin 1, intracellular mediator containing kelch motifs | 5396 | 0.023 | -0.1918 | No |
| 25 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 6696 | 0.004 | -0.2893 | No |
| 26 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 6884 | 0.002 | -0.3033 | No |
| 27 | CXCR3 | CXCR3 Entrez, Source | chemokine (C-X-C motif) receptor 3 | 7038 | -0.001 | -0.3147 | No |
| 28 | SERPINI2 | SERPINI2 Entrez, Source | serpin peptidase inhibitor, clade I (pancpin), member 2 | 7075 | -0.001 | -0.3173 | No |
| 29 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 7275 | -0.004 | -0.3319 | No |
| 30 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 7299 | -0.005 | -0.3332 | No |
| 31 | CRKL | CRKL Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 7585 | -0.009 | -0.3538 | No |
| 32 | CEECAM1 | CEECAM1 Entrez, Source | cerebral endothelial cell adhesion molecule 1 | 8251 | -0.019 | -0.4021 | No |
| 33 | PAFAH1B2 | PAFAH1B2 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa | 8363 | -0.021 | -0.4085 | No |
| 34 | CORO1A | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 8440 | -0.022 | -0.4121 | No |
| 35 | CSPG3 | CSPG3 Entrez, Source | chondroitin sulfate proteoglycan 3 (neurocan) | 8620 | -0.025 | -0.4231 | No |
| 36 | SPINT2 | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 8659 | -0.026 | -0.4235 | No |
| 37 | SELL | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 8867 | -0.029 | -0.4363 | No |
| 38 | CSPG4 | CSPG4 Entrez, Source | chondroitin sulfate proteoglycan 4 (melanoma-associated) | 9206 | -0.036 | -0.4583 | No |
| 39 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 9229 | -0.036 | -0.4564 | No |
| 40 | LIMK1 | LIMK1 Entrez, Source | LIM domain kinase 1 | 9254 | -0.037 | -0.4547 | No |
| 41 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9430 | -0.040 | -0.4640 | No |
| 42 | SERPINB5 | SERPINB5 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 9769 | -0.047 | -0.4849 | No |
| 43 | NTF3 | NTF3 Entrez, Source | neurotrophin 3 | 9863 | -0.049 | -0.4872 | No |
| 44 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 9982 | -0.052 | -0.4911 | No |
| 45 | FN1 | FN1 Entrez, Source | fibronectin 1 | 10062 | -0.053 | -0.4919 | No |
| 46 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 10092 | -0.054 | -0.4889 | No |
| 47 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 10153 | -0.056 | -0.4880 | No |
| 48 | IL8RB | IL8RB Entrez, Source | interleukin 8 receptor, beta | 10379 | -0.061 | -0.4991 | No |
| 49 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 10733 | -0.071 | -0.5189 | No |
| 50 | ADRA2A | ADRA2A Entrez, Source | adrenergic, alpha-2A-, receptor | 10829 | -0.073 | -0.5190 | No |
| 51 | IL13 | IL13 Entrez, Source | interleukin 13 | 11244 | -0.088 | -0.5417 | Yes |
| 52 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 11293 | -0.090 | -0.5367 | Yes |
| 53 | F11R | F11R Entrez, Source | F11 receptor | 11299 | -0.090 | -0.5283 | Yes |
| 54 | ACTB | ACTB Entrez, Source | actin, beta | 11552 | -0.102 | -0.5375 | Yes |
| 55 | KATNB1 | KATNB1 Entrez, Source | katanin p80 (WD repeat containing) subunit B 1 | 11624 | -0.106 | -0.5326 | Yes |
| 56 | NEO1 | NEO1 Entrez, Source | neogenin homolog 1 (chicken) | 11629 | -0.106 | -0.5227 | Yes |
| 57 | TNFRSF12A | TNFRSF12A Entrez, Source | tumor necrosis factor receptor superfamily, member 12A | 11673 | -0.108 | -0.5156 | Yes |
| 58 | ITGAL | ITGAL Entrez, Source | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 11774 | -0.112 | -0.5123 | Yes |
| 59 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 12015 | -0.126 | -0.5182 | Yes |
| 60 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 12035 | -0.127 | -0.5074 | Yes |
| 61 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12086 | -0.130 | -0.4985 | Yes |
| 62 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 12369 | -0.155 | -0.5049 | Yes |
| 63 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 12383 | -0.156 | -0.4908 | Yes |
| 64 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 12548 | -0.178 | -0.4859 | Yes |
| 65 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 12675 | -0.199 | -0.4762 | Yes |
| 66 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12871 | -0.243 | -0.4674 | Yes |
| 67 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 12879 | -0.245 | -0.4444 | Yes |
| 68 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12987 | -0.285 | -0.4250 | Yes |
| 69 | TPBG | TPBG Entrez, Source | trophoblast glycoprotein | 13238 | -0.524 | -0.3932 | Yes |
| 70 | NPY | NPY Entrez, Source | neuropeptide Y | 13255 | -0.563 | -0.3400 | Yes |
| 71 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13260 | -0.571 | -0.2852 | Yes |
| 72 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13282 | -0.665 | -0.2226 | Yes |
| 73 | MSN | MSN Entrez, Source | moesin | 13329 | -1.080 | -0.1218 | Yes |
| 74 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | 0.0005 | Yes |
