Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CELL_PROJECTION |
| Enrichment Score (ES) | -0.6049994 |
| Normalized Enrichment Score (NES) | -1.928951 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.013973243 |
| FWER p-Value | 0.42 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 455 | 0.214 | -0.0025 | No |
| 2 | CDH23 | CDH23 Entrez, Source | cadherin-like 23 | 720 | 0.171 | 0.0030 | No |
| 3 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 2178 | 0.089 | -0.0935 | No |
| 4 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 2539 | 0.078 | -0.1089 | No |
| 5 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2746 | 0.073 | -0.1137 | No |
| 6 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 2783 | 0.072 | -0.1057 | No |
| 7 | SI | SI Entrez, Source | sucrase-isomaltase (alpha-glucosidase) | 3180 | 0.063 | -0.1262 | No |
| 8 | CACNA1A | CACNA1A Entrez, Source | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 3272 | 0.061 | -0.1241 | No |
| 9 | AKAP4 | AKAP4 Entrez, Source | A kinase (PRKA) anchor protein 4 | 3280 | 0.061 | -0.1156 | No |
| 10 | DTNBP1 | DTNBP1 Entrez, Source | dystrobrevin binding protein 1 | 3520 | 0.056 | -0.1253 | No |
| 11 | PDPN | PDPN Entrez, Source | podoplanin | 4040 | 0.046 | -0.1576 | No |
| 12 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4604 | 0.036 | -0.1947 | No |
| 13 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 4962 | 0.030 | -0.2172 | No |
| 14 | SLC22A12 | SLC22A12 Entrez, Source | solute carrier family 22 (organic anion/cation transporter), member 12 | 4976 | 0.030 | -0.2138 | No |
| 15 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 5208 | 0.026 | -0.2273 | No |
| 16 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 5321 | 0.024 | -0.2321 | No |
| 17 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5854 | 0.016 | -0.2697 | No |
| 18 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 5959 | 0.015 | -0.2753 | No |
| 19 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 6000 | 0.014 | -0.2762 | No |
| 20 | TBC1D10A | TBC1D10A Entrez, Source | TBC1 domain family, member 10A | 6174 | 0.012 | -0.2875 | No |
| 21 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 6499 | 0.006 | -0.3110 | No |
| 22 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 6537 | 0.006 | -0.3129 | No |
| 23 | ESPN | ESPN Entrez, Source | espin | 6685 | 0.004 | -0.3233 | No |
| 24 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 7193 | -0.003 | -0.3611 | No |
| 25 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 7686 | -0.010 | -0.3966 | No |
| 26 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7883 | -0.013 | -0.4094 | No |
| 27 | DFNB31 | DFNB31 Entrez, Source | deafness, autosomal recessive 31 | 7942 | -0.014 | -0.4116 | No |
| 28 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 7982 | -0.015 | -0.4124 | No |
| 29 | ABI3 | ABI3 Entrez, Source | ABI gene family, member 3 | 8535 | -0.024 | -0.4504 | No |
| 30 | FGD1 | FGD1 Entrez, Source | FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) | 8576 | -0.024 | -0.4498 | No |
| 31 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 8872 | -0.029 | -0.4676 | No |
| 32 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 9419 | -0.040 | -0.5028 | No |
| 33 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 9556 | -0.043 | -0.5067 | No |
| 34 | SYNPO | SYNPO Entrez, Source | synaptopodin | 9931 | -0.051 | -0.5273 | No |
| 35 | DBNL | DBNL Entrez, Source | drebrin-like | 10207 | -0.057 | -0.5396 | No |
| 36 | GAS8 | GAS8 Entrez, Source | growth arrest-specific 8 | 10447 | -0.063 | -0.5483 | No |
| 37 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 10830 | -0.073 | -0.5662 | No |
| 38 | USH1C | USH1C Entrez, Source | Usher syndrome 1C (autosomal recessive, severe) | 11196 | -0.086 | -0.5809 | No |
| 39 | MYO5A | MYO5A Entrez, Source | myosin VA (heavy chain 12, myoxin) | 11281 | -0.090 | -0.5740 | No |
| 40 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11396 | -0.095 | -0.5685 | No |
| 41 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 11882 | -0.118 | -0.5875 | Yes |
| 42 | CTTN | CTTN Entrez, Source | cortactin | 11952 | -0.122 | -0.5746 | Yes |
| 43 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11968 | -0.123 | -0.5575 | Yes |
| 44 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 11985 | -0.124 | -0.5403 | Yes |
| 45 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 12002 | -0.125 | -0.5229 | Yes |
| 46 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12011 | -0.126 | -0.5048 | Yes |
| 47 | TLN1 | TLN1 Entrez, Source | talin 1 | 12039 | -0.127 | -0.4879 | Yes |
| 48 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12112 | -0.132 | -0.4737 | Yes |
| 49 | NEFH | NEFH Entrez, Source | neurofilament, heavy polypeptide 200kDa | 12123 | -0.133 | -0.4548 | Yes |
| 50 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12456 | -0.165 | -0.4553 | Yes |
| 51 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12577 | -0.181 | -0.4375 | Yes |
| 52 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12600 | -0.184 | -0.4118 | Yes |
| 53 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 12630 | -0.190 | -0.3858 | Yes |
| 54 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 12803 | -0.226 | -0.3652 | Yes |
| 55 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12871 | -0.243 | -0.3342 | Yes |
| 56 | MYO1C | MYO1C Entrez, Source | myosin IC | 13017 | -0.300 | -0.3006 | Yes |
| 57 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 13065 | -0.327 | -0.2556 | Yes |
| 58 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13099 | -0.355 | -0.2053 | Yes |
| 59 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13165 | -0.424 | -0.1473 | Yes |
| 60 | CLIC1 | CLIC1 Entrez, Source | chloride intracellular channel 1 | 13167 | -0.426 | -0.0842 | Yes |
| 61 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13279 | -0.655 | 0.0047 | Yes |
