Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CHANG_SERUM_RESPONSE_UP |
| Enrichment Score (ES) | -0.5363777 |
| Normalized Enrichment Score (NES) | -1.8677101 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.027333604 |
| FWER p-Value | 0.738 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PLG | PLG Entrez, Source | plasminogen | 81 | 0.434 | 0.0300 | No |
| 2 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 291 | 0.268 | 0.0365 | No |
| 3 | SRM | SRM Entrez, Source | spermidine synthase | 316 | 0.262 | 0.0564 | No |
| 4 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 405 | 0.229 | 0.0688 | No |
| 5 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 950 | 0.149 | 0.0402 | No |
| 6 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 974 | 0.147 | 0.0507 | No |
| 7 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 1014 | 0.144 | 0.0597 | No |
| 8 | IMP4 | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 1585 | 0.109 | 0.0257 | No |
| 9 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 1652 | 0.107 | 0.0296 | No |
| 10 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 2182 | 0.089 | -0.0029 | No |
| 11 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 2235 | 0.087 | 0.0004 | No |
| 12 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 2276 | 0.086 | 0.0045 | No |
| 13 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 2407 | 0.082 | 0.0015 | No |
| 14 | SSR3 | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 2461 | 0.081 | 0.0043 | No |
| 15 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 2764 | 0.072 | -0.0125 | No |
| 16 | MKKS | MKKS Entrez, Source | McKusick-Kaufman syndrome | 2769 | 0.072 | -0.0068 | No |
| 17 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 2936 | 0.068 | -0.0137 | No |
| 18 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 3035 | 0.066 | -0.0156 | No |
| 19 | MRPL37 | MRPL37 Entrez, Source | mitochondrial ribosomal protein L37 | 3397 | 0.058 | -0.0381 | No |
| 20 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 3418 | 0.058 | -0.0348 | No |
| 21 | RUVBL1 | RUVBL1 Entrez, Source | RuvB-like 1 (E. coli) | 3647 | 0.053 | -0.0476 | No |
| 22 | CENPJ | CENPJ Entrez, Source | centromere protein J | 3740 | 0.051 | -0.0503 | No |
| 23 | RPN1 | RPN1 Entrez, Source | ribophorin I | 4101 | 0.045 | -0.0737 | No |
| 24 | COX17 | COX17 Entrez, Source | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 4243 | 0.042 | -0.0809 | No |
| 25 | LYAR | LYAR Entrez, Source | - | 4619 | 0.036 | -0.1062 | No |
| 26 | GPLD1 | GPLD1 Entrez, Source | glycosylphosphatidylinositol specific phospholipase D1 | 4695 | 0.034 | -0.1090 | No |
| 27 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 5228 | 0.026 | -0.1470 | No |
| 28 | PCSK7 | PCSK7 Entrez, Source | proprotein convertase subtilisin/kexin type 7 | 5310 | 0.025 | -0.1511 | No |
| 29 | RNF138 | RNF138 Entrez, Source | ring finger protein 138 | 5579 | 0.021 | -0.1696 | No |
| 30 | DCLRE1B | DCLRE1B Entrez, Source | DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) | 5698 | 0.019 | -0.1769 | No |
| 31 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 5729 | 0.018 | -0.1777 | No |
| 32 | NUPL1 | NUPL1 Entrez, Source | nucleoporin like 1 | 5833 | 0.017 | -0.1840 | No |
| 33 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 5924 | 0.015 | -0.1896 | No |
| 34 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5972 | 0.015 | -0.1919 | No |
| 35 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 6773 | 0.003 | -0.2520 | No |
| 36 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 6888 | 0.001 | -0.2605 | No |
| 37 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 6950 | 0.000 | -0.2651 | No |
| 38 | DCK | DCK Entrez, Source | deoxycytidine kinase | 6967 | 0.000 | -0.2663 | No |
| 39 | CDCA4 | CDCA4 Entrez, Source | cell division cycle associated 4 | 6971 | 0.000 | -0.2665 | No |
| 40 | TXNL2 | TXNL2 Entrez, Source | thioredoxin-like 2 | 7061 | -0.001 | -0.2731 | No |
| 41 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 7153 | -0.002 | -0.2798 | No |
| 42 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 7156 | -0.002 | -0.2797 | No |
| 43 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 7196 | -0.003 | -0.2824 | No |
| 44 | VDAC1 | VDAC1 Entrez, Source | voltage-dependent anion channel 1 | 7242 | -0.004 | -0.2855 | No |
| 45 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 7492 | -0.007 | -0.3037 | No |
| 46 | WSB2 | WSB2 Entrez, Source | WD repeat and SOCS box-containing 2 | 7925 | -0.014 | -0.3351 | No |
| 47 | NUP107 | NUP107 Entrez, Source | nucleoporin 107kDa | 8038 | -0.015 | -0.3423 | No |
| 48 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 8216 | -0.018 | -0.3541 | No |
| 49 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 8236 | -0.019 | -0.3540 | No |
| 50 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 8385 | -0.021 | -0.3634 | No |
| 51 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 8508 | -0.023 | -0.3707 | No |
| 52 | PDAP1 | PDAP1 Entrez, Source | PDGFA associated protein 1 | 8543 | -0.024 | -0.3713 | No |
| 53 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8545 | -0.024 | -0.3694 | No |
| 54 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8589 | -0.025 | -0.3706 | No |
| 55 | NLN | NLN Entrez, Source | neurolysin (metallopeptidase M3 family) | 8790 | -0.028 | -0.3834 | No |
| 56 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 9022 | -0.033 | -0.3981 | No |
| 57 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 9358 | -0.039 | -0.4201 | No |
| 58 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 9648 | -0.045 | -0.4382 | No |
| 59 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 9750 | -0.047 | -0.4420 | No |
| 60 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 9770 | -0.047 | -0.4395 | No |
| 61 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 9778 | -0.047 | -0.4361 | No |
| 62 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10233 | -0.058 | -0.4656 | No |
| 63 | EMP2 | EMP2 Entrez, Source | epithelial membrane protein 2 | 10455 | -0.063 | -0.4770 | No |
| 64 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 10498 | -0.064 | -0.4748 | No |
| 65 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 10738 | -0.071 | -0.4870 | No |
| 66 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 10990 | -0.078 | -0.4994 | No |
| 67 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11071 | -0.081 | -0.4987 | No |
| 68 | GNG11 | GNG11 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 11 | 11199 | -0.086 | -0.5012 | No |
| 69 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 11211 | -0.086 | -0.4948 | No |
| 70 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 11411 | -0.095 | -0.5019 | No |
| 71 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 11555 | -0.102 | -0.5043 | No |
| 72 | TNFRSF12A | TNFRSF12A Entrez, Source | tumor necrosis factor receptor superfamily, member 12A | 11673 | -0.108 | -0.5041 | No |
| 73 | PFN1 | PFN1 Entrez, Source | profilin 1 | 11762 | -0.112 | -0.5015 | No |
| 74 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 12109 | -0.132 | -0.5166 | No |
| 75 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 12372 | -0.155 | -0.5235 | Yes |
| 76 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12413 | -0.160 | -0.5132 | Yes |
| 77 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12437 | -0.162 | -0.5015 | Yes |
| 78 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12449 | -0.164 | -0.4887 | Yes |
| 79 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12464 | -0.165 | -0.4760 | Yes |
| 80 | RNF41 | RNF41 Entrez, Source | ring finger protein 41 | 12523 | -0.174 | -0.4659 | Yes |
| 81 | CKLF | CKLF Entrez, Source | chemokine-like factor | 12616 | -0.187 | -0.4573 | Yes |
| 82 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12725 | -0.209 | -0.4481 | Yes |
| 83 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.4380 | Yes |
| 84 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.4250 | Yes |
| 85 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 13036 | -0.311 | -0.4010 | Yes |
| 86 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13129 | -0.381 | -0.3762 | Yes |
| 87 | SMS | SMS Entrez, Source | spermine synthase | 13163 | -0.420 | -0.3438 | Yes |
| 88 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13200 | -0.467 | -0.3077 | Yes |
| 89 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.2687 | Yes |
| 90 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13308 | -0.800 | -0.2100 | Yes |
| 91 | MSN | MSN Entrez, Source | moesin | 13329 | -1.080 | -0.1217 | Yes |
| 92 | TAGLN | TAGLN Entrez, Source | transgelin | 13339 | -1.475 | 0.0002 | Yes |
