Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CHIARETTI_T_ALL |
| Enrichment Score (ES) | -0.47840157 |
| Normalized Enrichment Score (NES) | -1.7349387 |
| Nominal p-value | 0.003215434 |
| FDR q-value | 0.05131316 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.284 | 0.0593 | No |
| 2 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 66 | 0.461 | 0.0756 | No |
| 3 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 243 | 0.289 | 0.0756 | No |
| 4 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 444 | 0.218 | 0.0705 | No |
| 5 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 459 | 0.213 | 0.0792 | No |
| 6 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 472 | 0.210 | 0.0880 | No |
| 7 | FXYD2 | FXYD2 Entrez, Source | FXYD domain containing ion transport regulator 2 | 480 | 0.207 | 0.0970 | No |
| 8 | TSHR | TSHR Entrez, Source | thyroid stimulating hormone receptor | 527 | 0.197 | 0.1026 | No |
| 9 | CD97 | CD97 Entrez, Source | CD97 molecule | 554 | 0.192 | 0.1095 | No |
| 10 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 557 | 0.191 | 0.1182 | No |
| 11 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 609 | 0.185 | 0.1228 | No |
| 12 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 613 | 0.184 | 0.1311 | No |
| 13 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 767 | 0.165 | 0.1271 | No |
| 14 | H1F0 | H1F0 Entrez, Source | H1 histone family, member 0 | 769 | 0.165 | 0.1347 | No |
| 15 | RCBTB2 | RCBTB2 Entrez, Source | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 796 | 0.163 | 0.1403 | No |
| 16 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 884 | 0.154 | 0.1408 | No |
| 17 | MAL | MAL Entrez, Source | mal, T-cell differentiation protein | 964 | 0.148 | 0.1416 | No |
| 18 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 965 | 0.148 | 0.1484 | No |
| 19 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 1114 | 0.136 | 0.1435 | No |
| 20 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 1150 | 0.133 | 0.1470 | No |
| 21 | SPON1 | SPON1 Entrez, Source | spondin 1, extracellular matrix protein | 1194 | 0.130 | 0.1497 | No |
| 22 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 1307 | 0.124 | 0.1470 | No |
| 23 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1413 | 0.118 | 0.1445 | No |
| 24 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 1449 | 0.116 | 0.1471 | No |
| 25 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1609 | 0.108 | 0.1401 | No |
| 26 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 1693 | 0.105 | 0.1387 | No |
| 27 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 1697 | 0.105 | 0.1433 | No |
| 28 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 1830 | 0.100 | 0.1379 | No |
| 29 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1863 | 0.099 | 0.1401 | No |
| 30 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 1935 | 0.096 | 0.1391 | No |
| 31 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 2281 | 0.086 | 0.1169 | No |
| 32 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 2287 | 0.085 | 0.1205 | No |
| 33 | RUNX3 | RUNX3 Entrez, Source | runt-related transcription factor 3 | 2426 | 0.082 | 0.1138 | No |
| 34 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 2927 | 0.068 | 0.0791 | No |
| 35 | ZBTB16 | ZBTB16 Entrez, Source | zinc finger and BTB domain containing 16 | 3183 | 0.063 | 0.0627 | No |
| 36 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 3416 | 0.058 | 0.0478 | No |
| 37 | SLC4A1 | SLC4A1 Entrez, Source | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 3668 | 0.053 | 0.0312 | No |
| 38 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 3790 | 0.050 | 0.0243 | No |
| 39 | CD2 | CD2 Entrez, Source | CD2 molecule | 3794 | 0.050 | 0.0264 | No |
| 40 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 3864 | 0.049 | 0.0234 | No |
| 41 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 3999 | 0.046 | 0.0154 | No |
| 42 | CD8A | CD8A Entrez, Source | CD8a molecule | 4174 | 0.043 | 0.0043 | No |
| 43 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 4177 | 0.043 | 0.0061 | No |
| 44 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 4260 | 0.042 | 0.0018 | No |
| 45 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 4784 | 0.033 | -0.0363 | No |
| 46 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 4803 | 0.032 | -0.0361 | No |
| 47 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 4822 | 0.032 | -0.0360 | No |
| 48 | IL12A | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 5271 | 0.025 | -0.0688 | No |
| 49 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 5321 | 0.024 | -0.0714 | No |
| 50 | ARID5A | ARID5A Entrez, Source | AT rich interactive domain 5A (MRF1-like) | 5334 | 0.024 | -0.0712 | No |
| 51 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 5520 | 0.021 | -0.0842 | No |
| 52 | ST18 | ST18 Entrez, Source | suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) | 5573 | 0.021 | -0.0872 | No |
| 53 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 5606 | 0.020 | -0.0887 | No |
| 54 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 5860 | 0.016 | -0.1071 | No |
| 55 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 5901 | 0.016 | -0.1094 | No |
| 56 | IGJ | IGJ Entrez, Source | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 5937 | 0.015 | -0.1113 | No |
| 57 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 6039 | 0.014 | -0.1184 | No |
| 58 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6041 | 0.014 | -0.1178 | No |
| 59 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 6114 | 0.013 | -0.1227 | No |
| 60 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 6200 | 0.011 | -0.1286 | No |
| 61 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6257 | 0.010 | -0.1324 | No |
| 62 | LMO4 | LMO4 Entrez, Source | LIM domain only 4 | 6402 | 0.008 | -0.1429 | No |
| 63 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 6522 | 0.006 | -0.1516 | No |
| 64 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 6567 | 0.006 | -0.1547 | No |
| 65 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 6673 | 0.004 | -0.1625 | No |
| 66 | GARNL1 | GARNL1 Entrez, Source | GTPase activating Rap/RanGAP domain-like 1 | 6825 | 0.002 | -0.1738 | No |
| 67 | CD52 | CD52 Entrez, Source | CD52 molecule | 7261 | -0.004 | -0.2066 | No |
| 68 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 7275 | -0.004 | -0.2074 | No |
| 69 | LAT | LAT Entrez, Source | linker for activation of T cells | 7393 | -0.006 | -0.2159 | No |
| 70 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 7434 | -0.006 | -0.2187 | No |
| 71 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 7577 | -0.009 | -0.2290 | No |
| 72 | CD200 | CD200 Entrez, Source | CD200 molecule | 7661 | -0.010 | -0.2349 | No |
| 73 | SNF1LK | SNF1LK Entrez, Source | SNF1-like kinase | 7785 | -0.012 | -0.2436 | No |
| 74 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 7803 | -0.012 | -0.2444 | No |
| 75 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 7850 | -0.013 | -0.2473 | No |
| 76 | TSC22D3 | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 7885 | -0.013 | -0.2492 | No |
| 77 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 7928 | -0.014 | -0.2517 | No |
| 78 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 8065 | -0.016 | -0.2613 | No |
| 79 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 8313 | -0.020 | -0.2791 | No |
| 80 | GAB2 | GAB2 Entrez, Source | GRB2-associated binding protein 2 | 8676 | -0.026 | -0.3053 | No |
| 81 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 8685 | -0.026 | -0.3047 | No |
| 82 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 8704 | -0.026 | -0.3049 | No |
| 83 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 8843 | -0.029 | -0.3140 | No |
| 84 | SELL | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 8867 | -0.029 | -0.3144 | No |
| 85 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 9109 | -0.034 | -0.3311 | No |
| 86 | FRMD4B | FRMD4B Entrez, Source | FERM domain containing 4B | 9272 | -0.037 | -0.3416 | No |
| 87 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 9276 | -0.037 | -0.3401 | No |
| 88 | CLEC11A | CLEC11A Entrez, Source | C-type lectin domain family 11, member A | 9394 | -0.040 | -0.3471 | No |
| 89 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 9523 | -0.042 | -0.3549 | No |
| 90 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 9556 | -0.043 | -0.3553 | No |
| 91 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 9787 | -0.048 | -0.3706 | No |
| 92 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 10111 | -0.055 | -0.3925 | No |
| 93 | AQP3 | AQP3 Entrez, Source | aquaporin 3 (Gill blood group) | 10174 | -0.056 | -0.3946 | No |
| 94 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 10405 | -0.062 | -0.4092 | No |
| 95 | EPHB6 | EPHB6 Entrez, Source | EPH receptor B6 | 10473 | -0.064 | -0.4114 | No |
| 96 | CTSH | CTSH Entrez, Source | cathepsin H | 10687 | -0.069 | -0.4243 | No |
| 97 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 10891 | -0.075 | -0.4362 | No |
| 98 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 11162 | -0.084 | -0.4528 | No |
| 99 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11463 | -0.098 | -0.4710 | No |
| 100 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 11562 | -0.102 | -0.4737 | Yes |
| 101 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 11588 | -0.104 | -0.4708 | Yes |
| 102 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 11637 | -0.106 | -0.4695 | Yes |
| 103 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 11671 | -0.108 | -0.4671 | Yes |
| 104 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 11723 | -0.110 | -0.4659 | Yes |
| 105 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 11745 | -0.111 | -0.4623 | Yes |
| 106 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 11788 | -0.113 | -0.4603 | Yes |
| 107 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11886 | -0.118 | -0.4622 | Yes |
| 108 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 12002 | -0.125 | -0.4651 | Yes |
| 109 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 12012 | -0.126 | -0.4600 | Yes |
| 110 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 12128 | -0.133 | -0.4626 | Yes |
| 111 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 12179 | -0.137 | -0.4600 | Yes |
| 112 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12184 | -0.138 | -0.4540 | Yes |
| 113 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 12223 | -0.142 | -0.4503 | Yes |
| 114 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 12294 | -0.147 | -0.4488 | Yes |
| 115 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12310 | -0.149 | -0.4431 | Yes |
| 116 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12381 | -0.156 | -0.4412 | Yes |
| 117 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 12395 | -0.157 | -0.4349 | Yes |
| 118 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 12467 | -0.166 | -0.4326 | Yes |
| 119 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 12553 | -0.179 | -0.4308 | Yes |
| 120 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12577 | -0.181 | -0.4242 | Yes |
| 121 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 12675 | -0.199 | -0.4224 | Yes |
| 122 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12680 | -0.201 | -0.4134 | Yes |
| 123 | PDLIM1 | PDLIM1 Entrez, Source | PDZ and LIM domain 1 (elfin) | 12713 | -0.207 | -0.4063 | Yes |
| 124 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 12774 | -0.218 | -0.4008 | Yes |
| 125 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 12812 | -0.228 | -0.3930 | Yes |
| 126 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12855 | -0.239 | -0.3852 | Yes |
| 127 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 12881 | -0.245 | -0.3758 | Yes |
| 128 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12889 | -0.247 | -0.3649 | Yes |
| 129 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12906 | -0.254 | -0.3544 | Yes |
| 130 | RAP2B | RAP2B Entrez, Source | RAP2B, member of RAS oncogene family | 13030 | -0.307 | -0.3496 | Yes |
| 131 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13080 | -0.340 | -0.3376 | Yes |
| 132 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13174 | -0.431 | -0.3247 | Yes |
| 133 | S100A4 | S100A4 Entrez, Source | S100 calcium binding protein A4 | 13202 | -0.468 | -0.3052 | Yes |
| 134 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13204 | -0.471 | -0.2835 | Yes |
| 135 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13286 | -0.695 | -0.2576 | Yes |
| 136 | CD69 | CD69 Entrez, Source | CD69 molecule | 13310 | -0.833 | -0.2209 | Yes |
| 137 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13321 | -0.988 | -0.1761 | Yes |
| 138 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13322 | -0.989 | -0.1305 | Yes |
| 139 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | -0.0728 | Yes |
| 140 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
