Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CMV_24HRS_DN |
| Enrichment Score (ES) | -0.5711488 |
| Normalized Enrichment Score (NES) | -1.7797778 |
| Nominal p-value | 0.0017421603 |
| FDR q-value | 0.040188674 |
| FWER p-Value | 0.992 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 50 | 0.500 | 0.0538 | No |
| 2 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 1078 | 0.138 | -0.0075 | No |
| 3 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 1087 | 0.138 | 0.0078 | No |
| 4 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 1090 | 0.138 | 0.0235 | No |
| 5 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 1288 | 0.125 | 0.0230 | No |
| 6 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 1619 | 0.108 | 0.0106 | No |
| 7 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 1910 | 0.097 | -0.0000 | No |
| 8 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 2189 | 0.088 | -0.0108 | No |
| 9 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 2259 | 0.086 | -0.0060 | No |
| 10 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 2586 | 0.077 | -0.0217 | No |
| 11 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 2971 | 0.067 | -0.0429 | No |
| 12 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 3063 | 0.065 | -0.0422 | No |
| 13 | EPO | EPO Entrez, Source | erythropoietin | 3095 | 0.064 | -0.0372 | No |
| 14 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3241 | 0.061 | -0.0410 | No |
| 15 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 3399 | 0.058 | -0.0461 | No |
| 16 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 3631 | 0.053 | -0.0574 | No |
| 17 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 3728 | 0.051 | -0.0587 | No |
| 18 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3797 | 0.050 | -0.0581 | No |
| 19 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 3828 | 0.049 | -0.0547 | No |
| 20 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 3981 | 0.047 | -0.0607 | No |
| 21 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4057 | 0.045 | -0.0612 | No |
| 22 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 5252 | 0.025 | -0.1481 | No |
| 23 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 6610 | 0.005 | -0.2496 | No |
| 24 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6709 | 0.004 | -0.2565 | No |
| 25 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 6773 | 0.003 | -0.2610 | No |
| 26 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 7375 | -0.006 | -0.3055 | No |
| 27 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.3545 | No |
| 28 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 8887 | -0.030 | -0.4139 | No |
| 29 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 9229 | -0.036 | -0.4354 | No |
| 30 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 9383 | -0.039 | -0.4424 | No |
| 31 | CHN1 | CHN1 Entrez, Source | chimerin (chimaerin) 1 | 9568 | -0.043 | -0.4513 | No |
| 32 | HIVEP2 | HIVEP2 Entrez, Source | human immunodeficiency virus type I enhancer binding protein 2 | 10603 | -0.067 | -0.5214 | No |
| 33 | ADRA2A | ADRA2A Entrez, Source | adrenergic, alpha-2A-, receptor | 10829 | -0.073 | -0.5299 | No |
| 34 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 11279 | -0.089 | -0.5534 | Yes |
| 35 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 11379 | -0.094 | -0.5500 | Yes |
| 36 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11463 | -0.098 | -0.5450 | Yes |
| 37 | C1R | C1R Entrez, Source | complement component 1, r subcomponent | 11480 | -0.099 | -0.5348 | Yes |
| 38 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 11551 | -0.102 | -0.5284 | Yes |
| 39 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12008 | -0.126 | -0.5482 | Yes |
| 40 | RAB13 | RAB13 Entrez, Source | RAB13, member RAS oncogene family | 12265 | -0.145 | -0.5508 | Yes |
| 41 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.5508 | Yes |
| 42 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12541 | -0.177 | -0.5306 | Yes |
| 43 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 12584 | -0.182 | -0.5129 | Yes |
| 44 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12929 | -0.262 | -0.5086 | Yes |
| 45 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 12978 | -0.283 | -0.4796 | Yes |
| 46 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.4478 | Yes |
| 47 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13073 | -0.336 | -0.4138 | Yes |
| 48 | SGCG | SGCG Entrez, Source | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 13075 | -0.336 | -0.3751 | Yes |
| 49 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13085 | -0.343 | -0.3364 | Yes |
| 50 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13125 | -0.378 | -0.2958 | Yes |
| 51 | ADM | ADM Entrez, Source | adrenomedullin | 13287 | -0.697 | -0.2277 | Yes |
| 52 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13299 | -0.740 | -0.1433 | Yes |
| 53 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13336 | -1.272 | 0.0005 | Yes |
