Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CROONQUIST_IL6_STROMA_UP |
| Enrichment Score (ES) | -0.64920664 |
| Normalized Enrichment Score (NES) | -1.8027531 |
| Nominal p-value | 0.003539823 |
| FDR q-value | 0.036944244 |
| FWER p-Value | 0.962 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.284 | 0.1934 | No |
| 2 | GABBR2 | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 1650 | 0.107 | 0.0856 | No |
| 3 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 2241 | 0.087 | 0.0543 | No |
| 4 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 2245 | 0.086 | 0.0671 | No |
| 5 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 3018 | 0.066 | 0.0191 | No |
| 6 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 3728 | 0.051 | -0.0265 | No |
| 7 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 4784 | 0.033 | -0.1007 | No |
| 8 | LOXL1 | LOXL1 Entrez, Source | lysyl oxidase-like 1 | 4974 | 0.030 | -0.1105 | No |
| 9 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 5548 | 0.021 | -0.1504 | No |
| 10 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 5633 | 0.020 | -0.1537 | No |
| 11 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 6461 | 0.007 | -0.2147 | No |
| 12 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 6673 | 0.004 | -0.2299 | No |
| 13 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 6696 | 0.004 | -0.2310 | No |
| 14 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6709 | 0.004 | -0.2313 | No |
| 15 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 7239 | -0.004 | -0.2705 | No |
| 16 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 8051 | -0.016 | -0.3291 | No |
| 17 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 8065 | -0.016 | -0.3277 | No |
| 18 | IER3 | IER3 Entrez, Source | immediate early response 3 | 9311 | -0.038 | -0.4155 | No |
| 19 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 10171 | -0.056 | -0.4716 | No |
| 20 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12537 | -0.177 | -0.6226 | Yes |
| 21 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12710 | -0.207 | -0.6044 | Yes |
| 22 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 12881 | -0.245 | -0.5803 | Yes |
| 23 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 12920 | -0.259 | -0.5441 | Yes |
| 24 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13125 | -0.378 | -0.5026 | Yes |
| 25 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13260 | -0.571 | -0.4266 | Yes |
| 26 | LOX | LOX Entrez, Source | lysyl oxidase | 13315 | -0.896 | -0.2958 | Yes |
| 27 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13321 | -0.988 | -0.1475 | Yes |
| 28 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13322 | -0.989 | 0.0015 | Yes |
