Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_72h_versus_single_gel_72h.class.cls #double_gel_72h_versus_single_gel_72h_repos |
| Phenotype | class.cls#double_gel_72h_versus_single_gel_72h_repos |
| Upregulated in class | single_gel_72h |
| GeneSet | CYTOSKELETAL_PART |
| Enrichment Score (ES) | -0.63253546 |
| Normalized Enrichment Score (NES) | -2.2563612 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 314 | 0.263 | -0.0020 | No |
| 2 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 804 | 0.162 | -0.0255 | No |
| 3 | CABP1 | CABP1 Entrez, Source | calcium binding protein 1 (calbrain) | 839 | 0.159 | -0.0149 | No |
| 4 | KATNA1 | KATNA1 Entrez, Source | katanin p60 (ATPase-containing) subunit A 1 | 1345 | 0.122 | -0.0430 | No |
| 5 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 1352 | 0.121 | -0.0334 | No |
| 6 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 2130 | 0.090 | -0.0847 | No |
| 7 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 2763 | 0.072 | -0.1265 | No |
| 8 | DRD2 | DRD2 Entrez, Source | dopamine receptor D2 | 3162 | 0.063 | -0.1513 | No |
| 9 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 3680 | 0.052 | -0.1861 | No |
| 10 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 4128 | 0.044 | -0.2162 | No |
| 11 | CACNA1C | CACNA1C Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1C subunit | 4205 | 0.043 | -0.2184 | No |
| 12 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4604 | 0.036 | -0.2455 | No |
| 13 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 4710 | 0.034 | -0.2506 | No |
| 14 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4891 | 0.031 | -0.2616 | No |
| 15 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 4962 | 0.030 | -0.2644 | No |
| 16 | ATG4B | ATG4B Entrez, Source | ATG4 autophagy related 4 homolog B (S. cerevisiae) | 5885 | 0.016 | -0.3328 | No |
| 17 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 5924 | 0.015 | -0.3344 | No |
| 18 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 5959 | 0.015 | -0.3357 | No |
| 19 | GFAP | GFAP Entrez, Source | glial fibrillary acidic protein | 5960 | 0.015 | -0.3345 | No |
| 20 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 6164 | 0.012 | -0.3489 | No |
| 21 | TPT1 | TPT1 Entrez, Source | tumor protein, translationally-controlled 1 | 6352 | 0.009 | -0.3623 | No |
| 22 | DYNLL2 | DYNLL2 Entrez, Source | dynein, light chain, LC8-type 2 | 6549 | 0.006 | -0.3766 | No |
| 23 | STAU1 | STAU1 Entrez, Source | staufen, RNA binding protein, homolog 1 (Drosophila) | 6669 | 0.004 | -0.3852 | No |
| 24 | ESPN | ESPN Entrez, Source | espin | 6685 | 0.004 | -0.3860 | No |
| 25 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 6718 | 0.004 | -0.3882 | No |
| 26 | TBCE | TBCE Entrez, Source | tubulin-specific chaperone e | 6963 | 0.000 | -0.4066 | No |
| 27 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 7074 | -0.001 | -0.4148 | No |
| 28 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 7116 | -0.002 | -0.4177 | No |
| 29 | MEFV | MEFV Entrez, Source | Mediterranean fever | 7182 | -0.003 | -0.4224 | No |
| 30 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 7285 | -0.004 | -0.4297 | No |
| 31 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 7348 | -0.005 | -0.4340 | No |
| 32 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 7406 | -0.006 | -0.4378 | No |
| 33 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 7686 | -0.010 | -0.4580 | No |
| 34 | AKAP9 | AKAP9 Entrez, Source | A kinase (PRKA) anchor protein (yotiao) 9 | 7704 | -0.010 | -0.4585 | No |
| 35 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 7754 | -0.011 | -0.4612 | No |
| 36 | ACTR1B | ACTR1B Entrez, Source | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | 7815 | -0.012 | -0.4647 | No |
| 37 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 7962 | -0.014 | -0.4746 | No |
| 38 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 8017 | -0.015 | -0.4774 | No |
| 39 | MYH7 | MYH7 Entrez, Source | myosin, heavy chain 7, cardiac muscle, beta | 8532 | -0.024 | -0.5143 | No |
| 40 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 8581 | -0.024 | -0.5159 | No |
| 41 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 8736 | -0.027 | -0.5253 | No |
| 42 | CETN3 | CETN3 Entrez, Source | centrin, EF-hand protein, 3 (CDC31 homolog, yeast) | 8746 | -0.027 | -0.5237 | No |
| 43 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 9043 | -0.033 | -0.5434 | No |
| 44 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9129 | -0.035 | -0.5469 | No |
| 45 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 9135 | -0.035 | -0.5444 | No |
| 46 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 9229 | -0.036 | -0.5485 | No |
| 47 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 9267 | -0.037 | -0.5482 | No |
| 48 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 9270 | -0.037 | -0.5452 | No |
| 49 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 9345 | -0.039 | -0.5476 | No |
| 50 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 9358 | -0.039 | -0.5453 | No |
| 51 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 9748 | -0.047 | -0.5709 | No |
| 52 | APC | APC Entrez, Source | adenomatosis polyposis coli | 9845 | -0.049 | -0.5741 | No |
| 53 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 9900 | -0.050 | -0.5740 | No |
| 54 | CETN1 | CETN1 Entrez, Source | centrin, EF-hand protein, 1 | 10032 | -0.053 | -0.5796 | No |
| 55 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 10153 | -0.056 | -0.5840 | No |
| 56 | TSGA14 | TSGA14 Entrez, Source | testis specific, 14 | 10166 | -0.056 | -0.5803 | No |
| 57 | SEPT9 | SEPT9 Entrez, Source | septin 9 | 10261 | -0.058 | -0.5826 | No |
| 58 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 10318 | -0.060 | -0.5819 | No |
| 59 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 10348 | -0.060 | -0.5791 | No |
| 60 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 10358 | -0.060 | -0.5748 | No |
| 61 | GAS8 | GAS8 Entrez, Source | growth arrest-specific 8 | 10447 | -0.063 | -0.5762 | No |
| 62 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 10686 | -0.069 | -0.5885 | No |
| 63 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 10830 | -0.073 | -0.5932 | No |
| 64 | DCTN1 | DCTN1 Entrez, Source | dynactin 1 (p150, glued homolog, Drosophila) | 10978 | -0.078 | -0.5979 | No |
| 65 | HDAC6 | HDAC6 Entrez, Source | histone deacetylase 6 | 11173 | -0.085 | -0.6056 | No |
| 66 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 11531 | -0.101 | -0.6242 | Yes |
| 67 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 11553 | -0.102 | -0.6174 | Yes |
| 68 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 11576 | -0.103 | -0.6105 | Yes |
| 69 | CDK5RAP2 | CDK5RAP2 Entrez, Source | CDK5 regulatory subunit associated protein 2 | 11579 | -0.103 | -0.6021 | Yes |
| 70 | KATNB1 | KATNB1 Entrez, Source | katanin p80 (WD repeat containing) subunit B 1 | 11624 | -0.106 | -0.5967 | Yes |
| 71 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 11647 | -0.106 | -0.5896 | Yes |
| 72 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 11712 | -0.110 | -0.5853 | Yes |
| 73 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 11749 | -0.111 | -0.5788 | Yes |
| 74 | PCM1 | PCM1 Entrez, Source | pericentriolar material 1 | 11900 | -0.119 | -0.5803 | Yes |
| 75 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 11905 | -0.119 | -0.5708 | Yes |
| 76 | AURKA | AURKA Entrez, Source | aurora kinase A | 11917 | -0.119 | -0.5618 | Yes |
| 77 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 11950 | -0.122 | -0.5541 | Yes |
| 78 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11968 | -0.123 | -0.5452 | Yes |
| 79 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11979 | -0.123 | -0.5358 | Yes |
| 80 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 12015 | -0.126 | -0.5280 | Yes |
| 81 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 12035 | -0.127 | -0.5189 | Yes |
| 82 | DYNC1I1 | DYNC1I1 Entrez, Source | dynein, cytoplasmic 1, intermediate chain 1 | 12058 | -0.129 | -0.5099 | Yes |
| 83 | NDE1 | NDE1 Entrez, Source | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 12075 | -0.130 | -0.5004 | Yes |
| 84 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12086 | -0.130 | -0.4904 | Yes |
| 85 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 12109 | -0.132 | -0.4811 | Yes |
| 86 | MYO9B | MYO9B Entrez, Source | myosin IXB | 12134 | -0.133 | -0.4719 | Yes |
| 87 | SEPT7 | SEPT7 Entrez, Source | septin 7 | 12144 | -0.134 | -0.4615 | Yes |
| 88 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 12204 | -0.140 | -0.4544 | Yes |
| 89 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12231 | -0.142 | -0.4446 | Yes |
| 90 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 12256 | -0.144 | -0.4345 | Yes |
| 91 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12456 | -0.165 | -0.4359 | Yes |
| 92 | DYNC1LI2 | DYNC1LI2 Entrez, Source | dynein, cytoplasmic 1, light intermediate chain 2 | 12539 | -0.177 | -0.4275 | Yes |
| 93 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 12548 | -0.178 | -0.4134 | Yes |
| 94 | KIF3C | KIF3C Entrez, Source | kinesin family member 3C | 12599 | -0.184 | -0.4019 | Yes |
| 95 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 12656 | -0.196 | -0.3899 | Yes |
| 96 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 12692 | -0.203 | -0.3758 | Yes |
| 97 | PXN | PXN Entrez, Source | paxillin | 12740 | -0.211 | -0.3618 | Yes |
| 98 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 12793 | -0.222 | -0.3473 | Yes |
| 99 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12813 | -0.228 | -0.3299 | Yes |
| 100 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12815 | -0.228 | -0.3111 | Yes |
| 101 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 12818 | -0.229 | -0.2923 | Yes |
| 102 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 12914 | -0.257 | -0.2782 | Yes |
| 103 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12969 | -0.279 | -0.2592 | Yes |
| 104 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13011 | -0.297 | -0.2377 | Yes |
| 105 | MYO1C | MYO1C Entrez, Source | myosin IC | 13017 | -0.300 | -0.2133 | Yes |
| 106 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13086 | -0.343 | -0.1901 | Yes |
| 107 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 13178 | -0.436 | -0.1608 | Yes |
| 108 | VIM | VIM Entrez, Source | vimentin | 13227 | -0.506 | -0.1226 | Yes |
| 109 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.586 | 0.0002 | Yes |
