Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_72h_versus_single_gel_72h.class.cls
#double_gel_72h_versus_single_gel_72h_repos
Phenotypeclass.cls#double_gel_72h_versus_single_gel_72h_repos
Upregulated in classsingle_gel_72h
GeneSetCYTOSKELETON
Enrichment Score (ES)-0.63829786
Normalized Enrichment Score (NES)-2.3967547
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: CYTOSKELETON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GYS2GYS2
Entrez,  Source
glycogen synthase 2 (liver)3140.263-0.0116No
2DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)6860.175-0.0317No
3SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 48040.162-0.0330No
4LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing8380.159-0.0281No
5CABP1CABP1
Entrez,  Source
calcium binding protein 1 (calbrain)8390.159-0.0208No
6KATNA1KATNA1
Entrez,  Source
katanin p60 (ATPase-containing) subunit A 113450.122-0.0535No
7MYH6MYH6
Entrez,  Source
myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)13520.121-0.0483No
8MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 116530.107-0.0661No
9STOML2STOML2
Entrez,  Source
stomatin (EPB72)-like 221060.091-0.0962No
10SNIPSNIP
Entrez,  Source
-21220.090-0.0932No
11MYL3MYL3
Entrez,  Source
myosin, light chain 3, alkali; ventricular, skeletal, slow21300.090-0.0895No
12ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta21310.090-0.0853No
13TNNI3TNNI3
Entrez,  Source
troponin I type 3 (cardiac)27630.072-0.1299No
14FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)29300.068-0.1393No
15DRD2DRD2
Entrez,  Source
dopamine receptor D231620.063-0.1539No
16AKAP4AKAP4
Entrez,  Source
A kinase (PRKA) anchor protein 432800.061-0.1600No
17SLC4A1SLC4A1
Entrez,  Source
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)36680.053-0.1869No
18UXTUXT
Entrez,  Source
ubiquitously-expressed transcript36800.052-0.1853No
19MYL2MYL2
Entrez,  Source
myosin, light chain 2, regulatory, cardiac, slow36840.052-0.1831No
20UTRNUTRN
Entrez,  Source
utrophin (homologous to dystrophin)37870.050-0.1886No
21ABRAABRA
Entrez,  Source
actin-binding Rho activating protein40150.046-0.2037No
22ABCA2ABCA2
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 240970.045-0.2077No
23BMFBMF
Entrez,  Source
Bcl2 modifying factor41280.044-0.2080No
24CACNA1CCACNA1C
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1C subunit42050.043-0.2117No
25DNALI1DNALI1
Entrez,  Source
dynein, axonemal, light intermediate chain 146040.036-0.2403No
26DCXDCX
Entrez,  Source
doublecortex; lissencephaly, X-linked (doublecortin)47100.034-0.2467No
27TNNT2TNNT2
Entrez,  Source
troponin T type 2 (cardiac)48910.031-0.2589No
28WASLWASL
Entrez,  Source
Wiskott-Aldrich syndrome-like49510.030-0.2620No
29TSC1TSC1
Entrez,  Source
tuberous sclerosis 149620.030-0.2614No
30AVILAVIL
Entrez,  Source
advillin52680.025-0.2834No
31CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)53150.024-0.2858No
32ATG4BATG4B
Entrez,  Source
ATG4 autophagy related 4 homolog B (S. cerevisiae)58850.016-0.3282No
33BRCA2BRCA2
Entrez,  Source
breast cancer 2, early onset59240.015-0.3304No
34ALS2ALS2
Entrez,  Source
amyotrophic lateral sclerosis 2 (juvenile)59590.015-0.3323No
35GFAPGFAP
Entrez,  Source
glial fibrillary acidic protein59600.015-0.3316No
36NF2NF2
Entrez,  Source
neurofibromin 2 (bilateral acoustic neuroma)60180.014-0.3353No
37CDC16CDC16
Entrez,  Source
CDC16 cell division cycle 16 homolog (S. cerevisiae)61640.012-0.3458No
38RAE1RAE1
Entrez,  Source
RAE1 RNA export 1 homolog (S. pombe)62890.010-0.3547No
39AMPHAMPH
Entrez,  Source
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)62910.010-0.3543No
40TPT1TPT1
Entrez,  Source
tumor protein, translationally-controlled 163520.009-0.3585No
41DYNLL2DYNLL2
Entrez,  Source
dynein, light chain, LC8-type 265490.006-0.3731No
42STAU1STAU1
Entrez,  Source
staufen, RNA binding protein, homolog 1 (Drosophila)66690.004-0.3819No
43ESPNESPN
Entrez,  Source
espin66850.004-0.3829No
44NARFNARF
Entrez,  Source
nuclear prelamin A recognition factor67180.004-0.3852No
45HINT1HINT1
Entrez,  Source
histidine triad nucleotide binding protein 167630.003-0.3884No
46FSCN3FSCN3
Entrez,  Source
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)69190.001-0.4001No
47TBCETBCE
Entrez,  Source
tubulin-specific chaperone e69630.000-0.4034No
48NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)7074-0.001-0.4116No
49MAP1AMAP1A
Entrez,  Source
microtubule-associated protein 1A7116-0.002-0.4147No
50MEFVMEFV
Entrez,  Source
Mediterranean fever7182-0.003-0.4195No
51NUDT21NUDT21
Entrez,  Source
nudix (nucleoside diphosphate linked moiety X)-type motif 217285-0.004-0.4270No
52TNNC1TNNC1
Entrez,  Source
troponin C type 1 (slow)7348-0.005-0.4315No
53KIF5AKIF5A
Entrez,  Source
kinesin family member 5A7406-0.006-0.4355No
54DDX20DDX20
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 207488-0.007-0.4413No
55CCT3CCT3
Entrez,  Source
chaperonin containing TCP1, subunit 3 (gamma)7557-0.008-0.4461No
56NEFLNEFL
Entrez,  Source
neurofilament, light polypeptide 68kDa7686-0.010-0.4554No
57AKAP9AKAP9
Entrez,  Source
A kinase (PRKA) anchor protein (yotiao) 97704-0.010-0.4562No
58TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 37754-0.011-0.4594No
59HAP1HAP1
Entrez,  Source
huntingtin-associated protein 1 (neuroan 1)7797-0.012-0.4620No
60ACTR1BACTR1B
Entrez,  Source
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)7815-0.012-0.4627No
61MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)7962-0.014-0.4731No
62CEP57CEP57
Entrez,  Source
centrosomal protein 57kDa8017-0.015-0.4765No
63ARPC1AARPC1A
Entrez,  Source
actin related protein 2/3 complex, subunit 1A, 41kDa8191-0.018-0.4888No
64CTNNB1CTNNB1
Entrez,  Source
catenin (cadherin-associated protein), beta 1, 88kDa8312-0.020-0.4970No
65CCNA1CCNA1
Entrez,  Source
cyclin A18384-0.021-0.5014No
66CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A8440-0.022-0.5046No
67GABARAPL2GABARAPL2
Entrez,  Source
GABA(A) receptor-associated protein-like 28493-0.023-0.5075No
68MYH7MYH7
Entrez,  Source
myosin, heavy chain 7, cardiac muscle, beta8532-0.024-0.5093No
69ARHGEF2ARHGEF2
Entrez,  Source
rho/rac guanine nucleotide exchange factor (GEF) 28581-0.024-0.5118No
70ARHGDIAARHGDIA
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) alpha8656-0.026-0.5162No
71IVLIVL
Entrez,  Source
involucrin8669-0.026-0.5159No
72STOMSTOM
Entrez,  Source
stomatin8714-0.027-0.5180No
73PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)8736-0.027-0.5184No
74CETN3CETN3
Entrez,  Source
centrin, EF-hand protein, 3 (CDC31 homolog, yeast)8746-0.027-0.5178No
75MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 119043-0.033-0.5387No
76TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa9129-0.035-0.5436No
77POLBPOLB
Entrez,  Source
polymerase (DNA directed), beta9135-0.035-0.5424No
78PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa9229-0.036-0.5477No
79HIP1HIP1
Entrez,  Source
huntingtin interacting protein 19248-0.037-0.5474No
80KIFC3KIFC3
Entrez,  Source
kinesin family member C39267-0.037-0.5470No
81ZW10ZW10
Entrez,  Source
ZW10, kinetochore associated, homolog (Drosophila)9270-0.037-0.5454No
82MYOM1MYOM1
Entrez,  Source
myomesin 1 (skelemin) 185kDa9345-0.039-0.5493No
83TUBG1TUBG1
Entrez,  Source
tubulin, gamma 19358-0.039-0.5484No
84PTPN21PTPN21
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 219411-0.040-0.5505No
85KIF4AKIF4A
Entrez,  Source
kinesin family member 4A9748-0.047-0.5738No
86APCAPC
Entrez,  Source
adenomatosis polyposis coli9845-0.049-0.5789No
87APPBP2APPBP2
Entrez,  Source
amyloid beta precursor protein (cytoplasmic tail) binding protein 29900-0.050-0.5806No
88SYNPOSYNPO
Entrez,  Source
synaptopodin9931-0.051-0.5805No
89ABLIM2ABLIM2
Entrez,  Source
actin binding LIM protein family, member 210013-0.052-0.5843No
90CETN1CETN1
Entrez,  Source
centrin, EF-hand protein, 110032-0.053-0.5832No
91MARCKSMARCKS
Entrez,  Source
myristoylated alanine-rich protein kinase C substrate10092-0.054-0.5851No
92CAPZA2CAPZA2
Entrez,  Source
capping protein (actin filament) muscle Z-line, alpha 210153-0.056-0.5871No
93TSGA14TSGA14
Entrez,  Source
testis specific, 1410166-0.056-0.5854No
94SEPT9SEPT9
Entrez,  Source
septin 910261-0.058-0.5899No
95DCTN4DCTN4
Entrez,  Source
dynactin 4 (p62)10318-0.060-0.5913No
96DCTN2DCTN2
Entrez,  Source
dynactin 2 (p50)10348-0.060-0.5907No
97KIF1BKIF1B
Entrez,  Source
kinesin family member 1B10358-0.060-0.5886No
98GAS8GAS8
Entrez,  Source
growth arrest-specific 810447-0.063-0.5924No
99ACTL7BACTL7B
Entrez,  Source
actin-like 7B10635-0.068-0.6034No
100SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310686-0.069-0.6040No
101TRPC4TRPC4
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 410745-0.071-0.6051No
102MAPTMAPT
Entrez,  Source
microtubule-associated protein tau10830-0.073-0.6081No
103CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)10847-0.074-0.6059No
104DCTN1DCTN1
Entrez,  Source
dynactin 1 (p150, glued homolog, Drosophila)10978-0.078-0.6121No
105LYSTLYST
Entrez,  Source
lysosomal trafficking regulator11059-0.080-0.6145No
106TGM1TGM1
Entrez,  Source
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)11140-0.083-0.6167No
107TUBB2CTUBB2C
Entrez,  Source
tubulin, beta 2C11159-0.084-0.6141No
108HDAC6HDAC6
Entrez,  Source
histone deacetylase 611173-0.085-0.6112No
109KIF5BKIF5B
Entrez,  Source
kinesin family member 5B11531-0.101-0.6336Yes
110ACTBACTB
Entrez,  Source
actin, beta11552-0.102-0.6304Yes
111DYNLL1DYNLL1
Entrez,  Source
dynein, light chain, LC8-type 111553-0.102-0.6257Yes
112SLC9A3R1SLC9A3R1
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 111571-0.103-0.6222Yes
113SIRT2SIRT2
Entrez,  Source
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)11576-0.103-0.6177Yes
114CDK5RAP2CDK5RAP2
Entrez,  Source
CDK5 regulatory subunit associated protein 211579-0.103-0.6130Yes
115KATNB1KATNB1
Entrez,  Source
katanin p80 (WD repeat containing) subunit B 111624-0.106-0.6115Yes
116CKAP5CKAP5
Entrez,  Source
cytoskeleton associated protein 511647-0.106-0.6082Yes
117NUMA1NUMA1
Entrez,  Source
nuclear mitotic apparatus protein 111712-0.110-0.6080Yes
118CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 211749-0.111-0.6055Yes
119DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)11814-0.114-0.6051Yes
120PCM1PCM1
Entrez,  Source
pericentriolar material 111900-0.119-0.6060Yes
121PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 211904-0.119-0.6007Yes
122CDC27CDC27
Entrez,  Source
cell division cycle 2711905-0.119-0.5952Yes
123AURKAAURKA
Entrez,  Source
aurora kinase A11917-0.119-0.5905Yes
124NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 911950-0.122-0.5873Yes
125CTTNCTTN
Entrez,  Source
cortactin11952-0.122-0.5817Yes
126ACTN3ACTN3
Entrez,  Source
actinin, alpha 311968-0.123-0.5771Yes
127TPM3TPM3
Entrez,  Source
tropomyosin 311979-0.123-0.5721Yes
128ACTR3ACTR3
Entrez,  Source
ARP3 actin-related protein 3 homolog (yeast)12015-0.126-0.5689Yes
129ACTR2ACTR2
Entrez,  Source
ARP2 actin-related protein 2 homolog (yeast)12035-0.127-0.5644Yes
130DYNC1I1DYNC1I1
Entrez,  Source
dynein, cytoplasmic 1, intermediate chain 112058-0.129-0.5601Yes
131NDE1NDE1
Entrez,  Source
nudE nuclear distribution gene E homolog 1 (A. nidulans)12075-0.130-0.5553Yes
132ARPC5ARPC5
Entrez,  Source
actin related protein 2/3 complex, subunit 5, 16kDa12086-0.130-0.5500Yes
133MAPRE1MAPRE1
Entrez,  Source
microtubule-associated protein, RP/EB family, member 112109-0.132-0.5456Yes
134MYO9BMYO9B
Entrez,  Source
myosin IXB12134-0.133-0.5412Yes
135SEPT7SEPT7
Entrez,  Source
septin 712144-0.134-0.5357Yes
136CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)12154-0.135-0.5301Yes
137LASP1LASP1
Entrez,  Source
LIM and SH3 protein 112204-0.140-0.5273Yes
138CAPZBCAPZB
Entrez,  Source
capping protein (actin filament) muscle Z-line, beta12231-0.142-0.5227Yes
139CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)12256-0.144-0.5178Yes
140LSP1LSP1
Entrez,  Source
lymphocyte-specific protein 112383-0.156-0.5201Yes
141CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase12395-0.157-0.5136Yes
142BIN1BIN1
Entrez,  Source
bridging integrator 112397-0.157-0.5064Yes
143GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)12398-0.157-0.4991Yes
144SMTNSMTN
Entrez,  Source
smoothelin12423-0.161-0.4934Yes
145MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle12456-0.165-0.4882Yes
146KALRNKALRN
Entrez,  Source
kalirin, RhoGEF kinase12509-0.172-0.4841Yes
147DYNC1LI2DYNC1LI2
Entrez,  Source
dynein, cytoplasmic 1, light intermediate chain 212539-0.177-0.4781Yes
148ARPC1BARPC1B
Entrez,  Source
actin related protein 2/3 complex, subunit 1B, 41kDa12548-0.178-0.4704Yes
149CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 412577-0.181-0.4641Yes
150KIF3CKIF3C
Entrez,  Source
kinesin family member 3C12599-0.184-0.4572Yes
151DSPDSP
Entrez,  Source
desmoplakin12648-0.194-0.4518Yes
152BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)12656-0.196-0.4432Yes
153WASF1WASF1
Entrez,  Source
WAS protein family, member 112675-0.199-0.4353Yes
154CALD1CALD1
Entrez,  Source
caldesmon 112690-0.203-0.4269Yes
155ACTC1ACTC1
Entrez,  Source
actin, alpha, cardiac muscle 112692-0.203-0.4176Yes
156PXNPXN
Entrez,  Source
paxillin12740-0.211-0.4113Yes
157TPM4TPM4
Entrez,  Source
tropomyosin 412793-0.222-0.4049Yes
158WASF2WASF2
Entrez,  Source
WAS protein family, member 212803-0.226-0.3951Yes
159MAP1BMAP1B
Entrez,  Source
microtubule-associated protein 1B12813-0.228-0.3852Yes
160KIF2CKIF2C
Entrez,  Source
kinesin family member 2C12815-0.228-0.3746Yes
161CAPGCAPG
Entrez,  Source
capping protein (actin filament), gelsolin-like12818-0.229-0.3642Yes
162SORBS2SORBS2
Entrez,  Source
sorbin and SH3 domain containing 212846-0.236-0.3553Yes
163HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 112847-0.236-0.3443Yes
164CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 112914-0.257-0.3373Yes
165CCNB2CCNB2
Entrez,  Source
cyclin B212949-0.272-0.3273Yes
166MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle12969-0.279-0.3157Yes
167TUBBTUBB
Entrez,  Source
tubulin, beta13001-0.292-0.3045Yes
168TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)13011-0.297-0.2914Yes
169MYO1CMYO1C
Entrez,  Source
myosin IC13017-0.300-0.2779Yes
170CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 513065-0.327-0.2662Yes
171LMNB1LMNB1
Entrez,  Source
lamin B113086-0.343-0.2518Yes
172BASP1BASP1
Entrez,  Source
brain abundant, membrane attached signal protein 113112-0.366-0.2367Yes
173EML2EML2
Entrez,  Source
echinoderm microtubule associated protein like 213178-0.436-0.2213Yes
174VIMVIM
Entrez,  Source
vimentin13227-0.506-0.2014Yes
175PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513261-0.575-0.1772Yes
176MSNMSN
Entrez,  Source
moesin13329-1.080-0.1320Yes
177ANXA1ANXA1
Entrez,  Source
annexin A113336-1.272-0.0734Yes
178ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle13340-1.5860.0002Yes
Table: GSEA details [plain text format]



Fig 2: CYTOSKELETON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CYTOSKELETON: Random ES distribution   
Gene set null distribution of ES for CYTOSKELETON